Abstract: Substance F-0368 of the formula: ##STR1## or salts thereof is prepared by culturing Kitasatosporia sp. F-0368 in a culture medium thereby producing substance F-0368, and then isolating and collecting substance F-0368 from the culture medium.

Abstract: Disclosed in the present invention are: a substance F-0368 or salts thereof having the following structural formula ##STR1## a method for production of the substance F-0368 or salts thereof, wherein an F-0368-substance-producing-microorganism belonging to a genus Kitasatosporia is cultured, and the substance F-0368 is isolated and collected from the cultured substance; a method for production of the substance F-0368 or salts thereof, wherein 3-methyl-4-lower alkoxy carbonyl-2(5H)-furanone represented by the following general formula is subjected to hydrolytic reaction ##STR2## (where: R represents a straight or branched lower alkyl group having 1 to 6 carbon atoms); a composition which consists essentially of the substance F-0368 or salt thereof, a diluent permissible in the agricultural chemicals, and a carrier or an excipient; a preventive agent for plant diseases such as rice blast disease and bacterial leaf blight disease, which consists essentially of an effective amount of the substance F-0368 or salts

Abstract: Benzaminoethylphenoxycyclohexylacetic acid derivatives having the formula ##STR1## wherein R.sup.1 represents hydrogen atom, a halogen atom, hydroxyl group, a lower alkyl group or a lower alkoxy group; n is 1 or 2; and R.sup.2 represents hydrogen atom, a lower alkyl group which can have a substituent of phenyl group, a lower alkoxycarbonyl group, 3,3,5-trimethylcyclohexyloxycarbonyl group or a heterocyclic group; hexadecyl group; phenyl group which can have a substituent of a lower alkyl group, a lower alkoxy group, a lower alkoxycarbonyl group or a halogen atom; a cyclohexyl group or .alpha.-[4-(4-chlorobenzaminoethyl) phenoxy]-.alpha.-cyclohexylacetoxycyclohexyl group a antihyperlipidemic compositions thereof.

Abstract: Novel substituted oxy-cyclohexylacetic acid derivatives as antihyperlipidemic agents are given. The compounds have the formula ##STR1## wherein n is 1 or 2; m is 0, 1 or 2; R.sub.1 represents a halogen atom, trifluoromethyl, a lower alkyl, a lower alkoxy, a lower alkylcarbonyl, dimethylphenylmethyl, cyclohexyl, phenyl, halogenophenyl, phenoxy or halogenophenoxy group, and two of R.sub.1 groups can be bonded to form an orthocondensed saturated alkylene ring; Hal represents a halogen atom; and R.sub.2 represents a hydrogen atom or a lower alkyl group.

Abstract: Benzoyl phenoxy acetic acid derivatives having the formula ##STR1## wherein R.sub.1 represents hydrogen or halogen atom or a lower alkyl group or a lower alkoxyl group; and R.sub.2 represents hydrogen atom or a lower alkyl group which impart excellent antihyperlipidemic activity are provided.

Abstract: Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula ##STR1## WHEREIN R.sub.1 represents hydrogen, hydroxy, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,R.sub.2 represents hydrogen, halogen, hydroxy, vinyl, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,A represents carbonyl, methylene or a single bond, andN is an integer of 1 to 4.

Abstract: Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula ##STR1## WHEREIN R.sub.1 represents hydrogen, halogen, hydroxy, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,R.sub.2 represents hydrogen, halogen, hydroxy, vinyl, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,A represents carbonyl, methylene or a single bond, andn is an integer of 1 to 4.