Patents by Inventor Yasuhiro Ikeura

Yasuhiro Ikeura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8545873
    Abstract: A transdermal patch comprising a backing 2 and an adhesive layer 3 laminated on the backing 2, wherein the adhesive layer 3 comprises a rosin-based resin and petroleum resin as a tackifier, the total compounding amount of the rosin-based resin and the petroleum resin is in a range of 15% by mass to 50% by mass, and compounding amount of the petroleum resin is ? times by mass to 4 times by mass as that of the rosin-based resin.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: October 1, 2013
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Publication number: 20120171278
    Abstract: A transdermal patch comprising a backing 2 and an adhesive layer 3 laminated on the backing 2, wherein the adhesive layer 3 comprises a rosin-based resin and petroleum resin as a tackifier, the total compounding amount of the rosin-based resin and the petroleum resin is in a range of 15% by mass to 50% by mass, and compounding amount of the petroleum resin is 1/3 times by mass to 4 times by mass as that of the rosin-based resin.
    Type: Application
    Filed: March 13, 2012
    Publication date: July 5, 2012
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Yasunori TAKADA, Koji TANAKA, Yasuhiro IKEURA
  • Patent number: 8173156
    Abstract: An anti-inflammatory-containing plaster is provided. The anti-inflammatory-containing plaster may include, e.g., a styrene-isoprene-styrene block copolymer, a high molecular weight polyisobutylene, a low molecular weight polyisobutylene, a tackifier, a plasticizer, a dispersant, and an anti-inflammatory having a carboxyl group or a salt thereof. However, the anti-inflammatory-containing plaster does not contain L-menthol. The anti-inflammatory-containing plaster has medicament release rates of 20-64% by mass and 40-93% by mass at one hour and three hours, respectively.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: May 8, 2012
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasuhiro Ikeura, Miyuki Shinmura
  • Patent number: 8158145
    Abstract: A transdermal patch comprising a backing 2 and an adhesive layer 3 laminated on the backing 2, wherein the adhesive layer 3 comprises a rosin-based resin and petroleum resin as a tackifier, the total compounding amount of the rosin-based resin and the petroleum resin is in a range of 15% by mass to 50% by mass, and compounding amount of the petroleum resin is ? times by mass to 4 times by mass as that of the rosin-based resin.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: April 17, 2012
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Patent number: 7615237
    Abstract: Percutaneously absorbable preparations (preferably nonaqueous ones, particularly matrix-type patches or ointment), containing salt-form acidic drugs and characterized by being improved in the percutaneous absorbability of the drug by the incorporation of an addition salt of a basic substance therewith and by being lowly irritant to the skin; and a percutaneous absorption accelerator for salt-form acidic drugs, containing an addition salt of a basic substance.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: November 10, 2009
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Publication number: 20090258952
    Abstract: An anti-inflammatory-containing plaster is provided. The anti-inflammatory-containing plaster may include, e.g., a styrene-isoprene-styrene block copolymer, a high molecular weight polyisobutylene, a low molecular weight polyisobutylene, a tackifier, a plasticizer, a dispersant, and an anti-inflammatory having a carboxyl group or a salt thereof. However, the anti-inflammatory-containing plaster does not contain L-menthol. The anti-inflammatory-containing plaster has medicament release rates of 20-64% by mass and 40-93% by mass at one hour and three hours, respectively.
    Type: Application
    Filed: June 10, 2009
    Publication date: October 15, 2009
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Yasuhiro Ikeura, Miyuki Shinmura
  • Patent number: 7250546
    Abstract: This invention provides a patch with less skin stimulation, excellent in long time store stability and heat stability and having favorable tack during use. The patch comprising a styrene-isoprene-styrene block copolymer, polyisobutylene, tackifier, plasticizer and pharmaceutically effective ingredient, in which two or more kinds of polyisobutylene of different average molecular weight are used in combination and the viscosity of the adhesive of the patch is between 1500 and 30,000 poise (at 60° C.) and the tack of the patch is from 5 to 200 g/10 mm.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: July 31, 2007
    Assignee: Hisamitsu Pharmaceuticals Co., Inc.
    Inventors: Kiyomi Tsuruda, Yasuhiro Ikeura
  • Publication number: 20070083139
    Abstract: This invention provides a patch with less skin stimulation, excellent in long time store stability and heat stability and having favorable tack during use. The patch comprising a styrene-isoprene-styrene block copolymer, polyisobutylene, tackifier, plasticizer and pharmaceutically effective ingredient, in which two or more kinds of polyisobutylene of different average molecular weight are used in combination and the viscosity of the adhesive of the patch is between 1500 and 30,000 poise (at 60° C.) and the tack of the patch is from 5 to 200 g/10 mm.
    Type: Application
    Filed: December 5, 2006
    Publication date: April 12, 2007
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kiyomi Tsuruda, Yasuhiro Ikeura
  • Patent number: 7153522
    Abstract: Percutaneous sorbefacients comprising hexylene glycol and 1-menthol, more particularly, percutaneous sorbefacients for female hormones or derivatives thereof; and preparations for percutaneous absorption which comprise a styrene/isoprene/styrene block copolymer and/or polyisobutylene, a softener and a tackifier as the base components, hormones, in particular, follicle hormone and/or luteal hormone as the drug component and hexylene glycol and 1-menthol as a sorbefacient.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: December 26, 2006
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasuhiro Ikeura, Masayoshi Maki
  • Patent number: 6991095
    Abstract: Packaged patch (10) according to the invention comprises patch (2) situated in space (4) inside patch package (3) composed of laminated packaging material (1), and its edges are sealed. Laminated packaging material (1) comprises hygroscopic material layer (13) made of LDPE containing 20–40 wt % of an inorganic filler, situated between moisture-permeable material layer (14) made of LDPE and having a moisture permeability of 40–120 g/m2/day and a screen material layer which blocks penetration of moisture, etc. and is composed of HDPE layer (12) and aluminum foil (11). The saturation hygroscopicity of laminated packaging material (1) is 2–30 g/m2 under atmosphere conditions with a temperature of 25° C. and a relative humidity of 75%. This construction sufficiently reduces the effect of moisture on a drug in patch (2) and allows patch (2) to be held in a stable state for prolonged periods, while also improving the economy and handleability of patch package (3).
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: January 31, 2006
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Shinji Yamasoto, Yasuhiro Ikeura
  • Patent number: 6924410
    Abstract: A patch has a backing which has been subjected to an ultraviolet-screening processing, the backing usually being of one layer. The ultraviolet-screening processing usually uses an organic ultraviolet absorbent and/or an inorganic ultraviolet-screening agent. The patch can contain in its base a medicine of poor photo-stability and a non-steroidal anti-inflammatory analgesic.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: August 2, 2005
    Assignee: Hisamitsu Pharmaceutical Co., Ltd.
    Inventors: Kiyomi Tsuruda, Yasuhiro Ikeura
  • Publication number: 20050129748
    Abstract: A transdermal patch comprising a backing 2 and an adhesive layer 3 laminated on the backing 2, wherein the adhesive layer 3 comprises a rosin-based resin and petroleum resin as a tackifier, the total compounding amount of the rosin-based resin and the petroleum resin is in a range of 15% by mass to 50% by mass, and compounding amount of the petroleum resin is ? times by mass to 4 times by mass as that of the rosin-based resin.
    Type: Application
    Filed: February 19, 2003
    Publication date: June 16, 2005
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Patent number: 6844007
    Abstract: A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plaster does not contain crotamiton which is a solubilizer for the felbinac, the felbinac is uniformly dispersed in a semi-solubilized state in the plaster, wherein solubilized felbinac and microcrystalline felbinac coexist in the plaster, and a thickness of the plaster is 50-300 ?m.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: January 18, 2005
    Assignee: Hisamitsu Pharmaceutical Co., Ltd.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Patent number: 6833138
    Abstract: A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plaster does not contain crotamiton which is a solubilizer for the felbinac, the felbinac is uniformly dispersed in a semi-solubilized state in the plaster, wherein solubilized felbinac and microcrystalline felbinac coexist in the plaster, and a thickness of the plaster is 50-300 &mgr;m.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: December 21, 2004
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Publication number: 20040146548
    Abstract: It is intended to provide percutaneously absorbable patches having an improved percutaneous absorbability of an anti-inflammatory agent in the form of a salt and an improved stability. Namely, percutaneously absorbable patches having an adhesive base layer which contains an anti-inflammatory agent in the form of a salt, an ammonium salt compound, an absorption enhancer and/or a solubilizer.
    Type: Application
    Filed: November 25, 2003
    Publication date: July 29, 2004
    Inventors: Yasunori Takada, Koji Tanaka, Tomonori Kurita, Yasuhiro Ikeura
  • Publication number: 20040086555
    Abstract: A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plaster does not contain crotamiton which is a solubilizer for the felbinac, the felbinac is uniformly dispersed in a semi-solubilized state in the plaster, wherein solubilized felbinac and microcrystalline felbinac coexist in the plaster, and a thickness of the plaster is 50-300 &mgr;m.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 6, 2004
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Publication number: 20040086554
    Abstract: A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plaster does not contain crotamiton which is a solubilizer for the felbinac, the felbinac is uniformly dispersed in a semi-solubilized state in the plaster, wherein solubilized felbinac and microcrystalline felbinac coexist in the plaster, and a thickness of the plaster is 50-300 &mgr;m.
    Type: Application
    Filed: June 27, 2003
    Publication date: May 6, 2004
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Publication number: 20040039356
    Abstract: It is intended to provide compositions for external preparations (in particular, adhesive preparations) which are excellent in the skin permeability of the active ingredient, make it possible to give a compact preparation size and exert relieved skin irritation in percutaneous preparations, etc. to be used in, for example, hormone substitution therapy. Namely, compositions for external preparation which contain a vegetable oil and polyvinyl pyrrolidone as a sorbefacient and/or a dissolution aid; and adhesive preparations containing these compositions.
    Type: Application
    Filed: April 14, 2003
    Publication date: February 26, 2004
    Inventors: Masayoshi Maki, Yasuhiro Ikeura
  • Patent number: 6620430
    Abstract: A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plaster does not contain crotamiton which is a solubilizer for the felbinac, the felbinac is uniformly dispersed in a semi-solubilized state in the plaster, wherein solubilized felbinac and microcrystalline felbinac coexist in the plaster, and a thickness of the plaster is 50-300 &mgr;m.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: September 16, 2003
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yasunori Takada, Koji Tanaka, Yasuhiro Ikeura
  • Publication number: 20030149383
    Abstract: An antiinflammatory-containing plaster comprising 5-40% by mass of a styrene-isoprene-styrene block copolymer, 1-25% by mass of a high molecular weight polyisobutylene, 0.5-24% by mass of a low molecular weight polyisobutylene, 3-50% by mass of a tackifier, 20-70% by mass of a plasticizer, 0.01-7% by mass of a dispersant, and 0.1-8% by mass of an antiinflammatory having a carboxyl group or a salt thereof, but which contains no L-menthol, wherein the medicament release rate at one hour after the start of test is 20-64% by mass and the medicament release rate at three hours after the start of test is 40-93% by mass according to the water-releasing test using a rotating cylinder described in the release test as prescribed in United State Pharmacopoeia.
    Type: Application
    Filed: October 18, 2002
    Publication date: August 7, 2003
    Inventors: Yasuhiro Ikeura, Miyuki Shinmura