Abstract: The present invention is a stainless steel material having antibacterial properties and antiviral properties, the stainless steel material containing a Cu-rich region 3 in which the concentration of Cu is higher than the average Cu concentration in a matrix along grain boundaries in a surface 1 of the stainless steel material and a surface layer 2 located immediately below the surface of the stainless steel material, wherein the Cu-rich region 3 has Cu grain boundary layers 6 that extend continuously at a depth of 10 ?m to 200 ?m from the surface 1 of the stainless steel material, the average number of the Cu grain boundary layers 6 is 2.0 or more per 100 ?m of a distance parallel to the surface of the stainless steel material in a cross section orthogonal to the surface of the stainless steel material.

Abstract: Viral vector-producing cells with improved ability to produce viral vector, a production method thereof, a kit containing the same, a method for selecting viral vector-producing cells, and the like are provided. A viral vector-producing cell in which the expression of a protein derived from the viral vector-producing cell is regulated, specifically, the expression of the aforementioned protein is regulated as compared with that in the viral vector-producing cells before regulation of the expression or HEK293 cells (Accession number ATCC CRL1573) shows an improved ability to produce viral vectors.

Abstract: Provided is a method for producing non-enveloped viral particles, comprising a step for obtaining a fraction containing non-enveloped viral particles by removing precipitates which are produced in a step for adding a substance which reduces the solubility of proteins under acidic conditions and/or a substance which precipitates under acidic conditions to a neutral or basic sample containing non-enveloped viral particles, and acidifying the sample after the addition of the substance.

Abstract: Provided is a method for producing non-enveloped viral particles, comprising a step for obtaining a fraction containing non-enveloped viral particles by removing precipitates which are produced in a step for adding a substance which reduces the solubility of proteins under acidic conditions and/or a substance which precipitates under acidic conditions to a neutral or basic sample containing non-enveloped viral particles, and acidifying the sample after the addition of the substance.

Abstract: The present invention provides a method for efficiently manufacturing a non-enveloped virus with high purity without laborious operation by cultivating cells having the ability to produce a non-enveloped virus and bringing the cells and an acidic solution into contact with each other. A non-enveloped virus vector manufactured by the method of the present invention and a composition having the non-enveloped viral vector as an active ingredient are very useful as gene transfer methods in the fields of basic research and clinical application gene therapy.

Abstract: Provided are a production method for non-enveloped virus particles which is characterized in that a sample including non-envelopes virus particles is treated with PEG in at least two concentrations; a kit used in said production method; non-enveloped virus particles produced using said production method; and a pharmaceutical composition having the non-envelopes virus particles as an active ingredient.

Abstract: Provided are a production method for non-enveloped virus particles which is characterized in that a sample including non-envelopes virus particles is treated with PEG in at least two concentrations; a kit used in said production method; non-enveloped virus particles produced using said production method; and a pharmaceutical composition having the non-envelopes virus particles as an active ingredient.

Abstract: The present invention provides a method for efficiently manufacturing a non-enveloped virus with high purity without laborious operation by cultivating cells having the ability to produce a non-enveloped virus and bringing the cells and an acidic solution into contact with each other. A non-enveloped virus vector manufactured by the method of the present invention and a composition having the non-enveloped viral vector as an active ingredient are very useful as gene transfer methods in the fields of basic research and clinical application gene therapy.

Abstract: A frequency characteristics control device of a mixer mixes a first audio signal and a second audio signal inputted to the mixer. In the frequency characteristics control device, a characteristics detection section detects a first frequency characteristic of the first audio signal and a second frequency characteristic of the second audio signal. Based on the first and second frequency characteristics, a removal band detection section detects a removal band in which a level of the first audio signal is higher than a level of the second audio signal. A filtering process section performs a filtering process on the second audio signal so as to attenuate a component of the second audio signal in the removal band. A output section mixes the first audio signal inputted to the mixer and the second audio signal on which the filtering process section has performed the filtering process.

Abstract: User equipment includes a first communication entity that supports a transport layer protocol and a network layer protocol, and that transmits data a transmission source address of which is set to be a certain network layer address, to a network; and a second communication entity that supports the transport layer protocol and the network layer protocol, and that by commonly using the certain network layer address, is able to transmit the data the transmission source address of which is set to be the certain network layer address, to the network, wherein the second communication entity includes a storage device that stores a port number not being overlapping a port number which is used in the first communication entity, and a control device that performs determining processing which, when the received data does not include the port number, determines that the destination of the received data is the first communication entity.

Abstract: When musical performance data is input to the electronic musical instrument in accordance with user's operation for musical performance, the electronic musical instrument detects a chord in accordance with the input musical performance data at the defined timing T3 at which the chord detection timing ends. On the electronic musical instrument, furthermore, the application of the detected chord to the musical performance is instructed by user's pedal (foot switch) operation of turning off the pedal. In a case where the instruction to apply the chord has been already accepted at the chord detection timing T3 or in a case where the instruction to apply the chord has been accepted by user's pedal-off operation at a point in time (Tpf) situated between the chord detection timing T3 and the time limit T4, the detected chord is to be applied to the musical performance.

Abstract: It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.

Abstract: When musical performance data is input to the electronic musical instrument in accordance with user's operation for musical performance, the electronic musical instrument detects a chord in accordance with the input musical performance data at the defined timing T3 at which the chord detection timing ends. On the electronic musical instrument, furthermore, the application of the detected chord to the musical performance is instructed by user's pedal (foot switch) operation of turning off the pedal. In a case where the instruction to apply the chord has been already accepted at the chord detection timing T3 or in a case where the instruction to apply the chord has been accepted by user's pedal-off operation at a point in time (Tpf) situated between the chord detection timing T3 and the time limit T4, the detected chord is to be applied to the musical performance.

Abstract: A frequency characteristics control device of a mixer mixes a first audio signal and a second audio signal inputted to the mixer. In the frequency characteristics control device, a characteristics detection section detects a first frequency characteristic of the first audio signal and a second frequency characteristic of the second audio signal. Based on the first and second frequency characteristics, a removal band detection section detects a removal band in which a level of the first audio signal is higher than a level of the second audio signal. A filtering process section performs a filtering process on the second audio signal so as to attenuate a component of the second audio signal in the removal band. A output section mixes the first audio signal inputted to the mixer and the second audio signal on which the filtering process section has performed the filtering process.

Abstract: Disclosed is a prophylactic or therapeutic agent for bacterial infectious diseases, which comprises an antibody capable of binding to a toxin or an antitoxin that constitutes a bacterial toxin-antitoxin system to inhibit the interaction between the toxin and the antitoxin or a gene for the antibody as an active ingredient.

Abstract: It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.

Abstract: It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.

Abstract: An arpeggio playing apparatus comprises an arpeggio pattern storing device, an arpeggio pattern readout device and an arpeggio tone processing device. The arpeggio pattern storing device stores at least one arpeggio pattern pair including a regular version pattern and an accentuated version pattern for automatic arpeggio performances. When there comes a key-on event representing an arpeggio designation and a key-on velocity, the arpeggio pattern readout device reads out, from the arpeggio pattern storing device, the regular version pattern when the detected velocity is less than a predetermined threshold value, and the accentuated version pattern when the detected velocity is not less than the predetermined threshold value. The arpeggio tone processing device automatically plays arpeggio based on the arpeggio designation by the key-on event and according to the arpeggio patterns of the read-out versions.

Abstract: An arpeggio playing apparatus comprises a musical tone signal generating device including a plurality of arpeggio playing parts, or an automatic music playing device and at least one arpeggio playing part. The arpeggio playing part is capable of playing an automatic arpeggio with an arpeggio pattern at a progression tempo. Under the condition that one of the arpeggio playing parts or the automatic music playing device has started playing an automatic arpeggio or an automatic music performance at the progression tempo which defines a synchronization timing consisting of periodically aligned synchronization grids, when a start instruction for a new arpeggio playing part is received, the new arpeggio playing part starts the operation in synchronism with the defined synchronization timing.

Abstract: By a program process, CPU 31 embeds a watermark data into a waveform data stored in wave memory 41a. The program includes a step for detecting a characterizing part (attack part and loop part) of a waveform data that represents a waveform of a musical tone where the characterizing part represents characteristics of the musical tone, and a step for embedding a watermark data into a part of the waveform data excluding the detected characterizing part. Further, CPU 31 can also extract the watermark data by a program process including a step for detecting the characterizing part and a step for extracting the watermark data embedded in a part excluding the detected characterizing part. Thus, from waveform data including a watermark data, natural musical tones can be reproduced without deteriorating the characteristics of the musical tones at the time of reproduction.