Patents by Inventor Yasuhiro Komatsuki

Yasuhiro Komatsuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11225448
    Abstract: A method for manufacturing isopulegol includes the step of diastereoselective ring-closing a citronellal using an aluminum compound of formula (1) below. In formula (1), X represents a halogen atom, Y represents a halogen atom or a hydrogen atom, and R1 represents a phenyl group or a cycloalkyl group of 5 to 12 carbons.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: January 18, 2022
    Assignee: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yasuhiro Komatsuki, Kazuya Taira, Ayaka Koike, Kazuki Kimura
  • Publication number: 20210238115
    Abstract: A method for manufacturing isopulegol includes the step of diastereoselective ring-closing a citronellal using an aluminum compound of formula (1) below. In formula (1), X represents a halogen atom, Y represents a halogen atom or a hydrogen atom, and R1 represents a phenyl group or a cycloalkyl group of 5 to 12 carbons.
    Type: Application
    Filed: January 25, 2021
    Publication date: August 5, 2021
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yasuhiro KOMATSUKI, Kazuya TAIRA, Ayaka KOIKE, Kazuki KIMURA
  • Patent number: 9975831
    Abstract: An object of the present invention is to provide a method for producing an ether compound easily in a small number of steps at lower costs in high yields. The present invention relates to a method in which the ether compound represented by the general formula (1) is produced by reacting the specific carbonyl compound specified in the general formula (2) and the specific dialkoxy compound specified in the general formula (3) with hydrogen in the presence of a hydrogenation catalyst and an acidic substance to perform hydrogenation.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: May 22, 2018
    Assignee: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yasuhiro Komatsuki, Kenya Ishida, Kenji Yagi
  • Publication number: 20150011799
    Abstract: An object of the present invention is to provide a method for producing an ether compound easily in a small number of steps at lower costs in high yields. The present invention relates to a method in which the ether compound represented by the general formula (1) is produced by reacting the specific carbonyl compound specified in the general formula (2) and the specific dialkoxy compound specified in the general formula (3) with hydrogen in the presence of a hydrogenation catalyst and an acidic substance to perform hydrogenation.
    Type: Application
    Filed: February 5, 2013
    Publication date: January 8, 2015
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yasuhiro Komatsuki, Kenya Ishida, Kenji Yagi
  • Publication number: 20140219931
    Abstract: The present invention relates to a p-menthane-3,8-diol isomer mixture 50% by mass or more of which is constituted of (1S)-isomers and a cooling sensation composition containing this mixture. The present invention also relates to a flavor and/or fragrance composition, food, beverage, cosmetic, daily use product, oral cavity composition, or pharmaceutical containing the p-menthane-3,8-diol isomer mixture in an amount of 0.0001 to 90% by mass.
    Type: Application
    Filed: August 31, 2012
    Publication date: August 7, 2014
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Yasuhiro Komatsuki, Shigeru Tanaka, Kenya Ishida
  • Publication number: 20130245287
    Abstract: The present invention relates to a method comprising (A) reacting a ?-keto ester with a 2-halo ester under basic conditions to obtain a 2-aceto-3-methyl-succinic acid ester; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, optionally followed by a decarboxylation reaction and hydrolysis, etc., to obtain an ?-methyl-?-keto acid; and (C) reducing the resulting ?-methyl-?-keto acid to obtain wine lactone or a stereoisomer thereof or a mixture thereof.
    Type: Application
    Filed: May 6, 2013
    Publication date: September 19, 2013
    Applicant: Takasago International Corporation
    Inventors: Kenji Yagi, Yasuhiro Komatsuki, Hideo Ujihara, Kenya Ishida
  • Publication number: 20130245286
    Abstract: The present invention relates to a method comprising (A) reacting a ?-keto ester with a 2-halo ester under basic conditions to obtain a 2-aceto-3-methyl-succinic acid ester; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, optionally followed by a decarboxylation reaction and hydrolysis, etc., to obtain an ?-methyl-?-keto acid; and (C) reducing the resulting ?-methyl-?-keto acid to obtain wine lactone or a stereoisomer thereof or a mixture thereof.
    Type: Application
    Filed: May 6, 2013
    Publication date: September 19, 2013
    Applicant: Takasago International Corporation
    Inventors: Kenji Yagi, Yasuhiro Komatsuki, Hideo Ujihara, Kenya Ishida
  • Patent number: 8481759
    Abstract: The present invention relates to a method comprising (A) reacting a ?-keto ester with a 2-halo ester under basic conditions to obtain a 2-aceto-3-methyl-succinic acid ester; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, optionally followed by a decarboxylation reaction and hydrolysis, etc., to obtain an ?-methyl-?-keto acid; and (C) reducing the resulting ?-methyl-?-keto acid to obtain wine lactone or a stereoisomer thereof or a mixture thereof.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: July 9, 2013
    Assignee: Takasago International Corporation
    Inventors: Kenji Yagi, Yasuhiro Komatsuki, Hideo Ujihara, Kenya Ishida
  • Patent number: 8377458
    Abstract: Disclosed is a cooling sensation agent composition or sensory stimulation agent composition which contains at least one of diester compounds of dicarboxylic acid represented by the formula (1) wherein A represents CH2 or CH?CH, n represents an integer of 0 to 4 when A is CH2, or 1 when A is CH?CH, B is an alcohol residue having 10 to 18 carbon atoms and containing a para-menthane skeleton, which may have a substituent, and C is an alcohol residue having 6 to 18 carbon atoms, which may have a substituent as well as a flavor or fragrance composition, a beverage, a food product, a perfume or cosmetic product, a toiletry product, daily utensil products or groceries, a fiber, a fiber product, clothes, clothing or a medicine, wherein the cooling sensation agent composition or the sensory stimulation agent composition is compounded.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: February 19, 2013
    Assignee: Takasago International Corporation
    Inventors: Yasuhiro Komatsuki, Tomoko Yamamoto, Takashi Aida, Kenya Ishida
  • Publication number: 20130030193
    Abstract: The present invention relates to a method comprising (A) reacting a ?-keto ester with a 2-halo ester under basic conditions to obtain a 2-aceto-3-methyl-succinic acid ester; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, optionally followed by a decarboxylation reaction and hydrolysis, etc., to obtain an ?-methyl-?-keto acid; and (C) reducing the resulting ?-methyl-?-keto acid to obtain wine lactone or a stereoisomer thereof or a mixture thereof.
    Type: Application
    Filed: May 30, 2012
    Publication date: January 31, 2013
    Inventors: Kenji Yagi, Yasuhiro Komatsuki, Hideo Ujihara, Kenya Ishida
  • Publication number: 20110081393
    Abstract: Disclosed is a cooling sensation agent composition or sensory stimulation agent composition which contains at least one of diester compounds of dicarboxylic acid represented by the formula (1) wherein A represents CH2 or CH?CH, n represents an integer of 0 to 4 when A is CH2, or 1 when A is CH?CH, B is an alcohol residue having 10 to 18 carbon atoms and containing a para-menthane skeleton, which may have a substituent, and C is an alcohol residue having 6 to 18 carbon atoms, which may have a substituent as well as a flavor or fragrance composition, a beverage, a food product, a perfume or cosmetic product, a toiletry product, daily utensil products or groceries, a fiber, a fiber product, clothes, clothing or a medicine, wherein the cooling sensation agent composition or the sensory stimulation agent composition is compounded.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 7, 2011
    Inventors: Yasuhiro Komatsuki, Tomoko Yamamoto, Takashi Aida, Kenya Ishida