Abstract: A relay control device controls an operation of a relay circuit, which is disposed between a battery and an electric load, and the relay circuit is sealed in a case of a battery pack. The relay circuit includes: a first main relay disposed in a first conduction path which is connected to a first terminal of the battery; a second main relay disposed in a second conduction path which is connected to a second terminal of the battery; and a pre-charge relay connected to the second conduction path in parallel with the second main relay. The relay control device turns on the pre-charge relay, the first main relay, and the second main relay in order, and then turns off the pre-charge relay, the first main relay, and the second main relay in order.

Abstract: A first positioning hole is formed in a first positioning portion of a separator member, which is a fuel cell separator member forming a fuel cell stack. The first positioning portion includes a reinforcing rib and a joint portion. The reinforcing rib extends linearly outside the first positioning hole and protrudes from each of a first metal separator and a second metal separator. The joint portion is located between the reinforcing rib and the first positioning hole, and the first metal separator and the second metal separator are joined together at the joint portion.

Abstract: Disclosed herein are methods of increasing response to radiation therapy in subjects afflicted with cancer. In some embodiments, the method comprises reducing the ability of an immune suppressor cell (e.g., MDSC) to migrate to the microenvironment of the cancer. In some embodiments, the method further comprises suppressing the migration of the immune suppressor cell to a non-malignant cell and/or suppressing the malignant transformation of the non-malignant cells.

Abstract: Disclosed herein are methods of increasing response to radiation therapy in subjects afflicted with cancer. In some embodiments, the method comprises reducing the ability of an immune suppressor cell (e.g., MDSC) to migrate to the microenvironment of the cancer. In some embodiments, the method further comprises suppressing the migration of the immune suppressor cell to a non-malignant cell and/or suppressing the malignant transformation of the non-malignant cells.

Abstract: Disclosed herein are methods of increasing response to radiation therapy in subjects afflicted with cancer. In some embodiments, the method comprises reducing the ability of an immune suppressor cell (e.g., MDSC) to migrate to the microenvironment of the cancer. In some embodiments, the method further comprises suppressing the migration of the immune suppressor cell to a non-malignant cell and/or suppressing the malignant transformation of the non-malignant cells.

Abstract: The present invention is a granular material that can be well recoated regardless of the type of the granular material, and enables a refractory aggregate in an unprinted portion to be used without any regeneration process, in the manufacture of a three-dimensional laminated and shaped mold. This granular material is a granular material for use in three-dimensional laminated mold shaping, and obtained by adding a material that causes a hydration reaction having a moisture absorbing function and generates a catalytic effect to a coating material mixed with or coated with an acid as a catalyst which activates and hardens an organic binder for binding the granular material.

Abstract: In order to well perform recoating regardless of the type of granular material and reuse a refractory aggregate in an unprinted portion without any regeneration process in the manufacture of a three-dimensional lamination-shaped mold, this invention provides a granular material for use in shaping a three-dimensional laminated mold, which is coated with an acid as a catalyst which activates and cures an organic binder for binding the granular material. The acid contains at least one of sulfuric acid, phosphoric acid, a sulfonic acid and a carboxylic acid, and is one of a mixture of sulfuric acid and another acid, phosphoric acid only, a mixture of phosphoric acid and another acid, sulfonic acid only, a mixture of sulfonic acid and another acid and a mixture of a carboxylic acid and another acid.

Abstract: The present invention is a granular material that can be well recoated regardless of the type of the granular material, and enables a refractory aggregate in an unprinted portion to be used without any regeneration process, in the manufacture of a three-dimensional laminated and shaped mold. This granular material is a granular material for use in three-dimensional laminated mold shaping, and obtained by adding a material that causes a hydration reaction having a moisture absorbing function and generates a catalytic effect to a coating material mixed with or coated with an acid as a catalyst which activates and hardens an organic binder for binding the granular material.

Abstract: Provided is a granular material which generates no harmful gas at the time of pouring, reduces a gas defect as one of casting defects, and is readily reusable after pouring, in the manufacture of a three-dimensional laminated and shaped mold. This granular material is a granular material for use in a three-dimensional laminated and shaped mold manufacturing apparatus, and includes magnesium sulfate. The amount of magnesium sulfate included in the granular material is 1 to 10 pts·mass with respect to 100 pts·mass of the granular material. The amount of water included in the granular material is 0.1 mass % or less except for crystallization water of magnesium sulfate.

Abstract: The present invention provides a fusion proteins comprising (a) a first stretch of consecutive amino acids, the sequence of which is the sequence of an anti-p185her2/neu polypeptide or an anti-EGFR polypeptide; (b) a second stretch of consecutive amino acids, the sequence of which is the sequence of a polypeptide capable of binding at least one polypeptide other than p185her2/neu or EGFR; and (c) a third stretch of consecutive amino acids, the sequence of which comprises the sequence of a biologically active portion of interferon-gamma (IFN?), wherein (b) is located at the carboxy-terminal end of (a), and (c) is located at the carboxy-terminal end of (b). The present invention provides methods and compositions treating or preventing cancer and for sensitizing cancer cells to radiation or a chemotherapeutic agent, which comprises administering i) an anti-p185her2/neu antibody, an anti-EGFR antibody or an erbB kinase inhibitor and interferon-gamma (IFN?); or ii) a fusion protein of the invention.

Abstract: In order to generate no harmful gas during pouring and reduce a gas defect as one cast metal defect in the manufacture of a three-dimensional lamination-shaped mold, this invention provides a granular material for use in shaping a three-dimensional lamination mold, the granular material being coated with water glass which is activated and cured by a water-soluble ester. The residual water content in the granular material is 1% or less. The water glass is one of a sodium silicate solution, a potassium silicate solution, as alkali metal silicate solutions and a mixture thereof.

Abstract: In order to well perform recoating regardless of the type of granular material and reuse a refractory aggregate in an unprinted portion without any regeneration process in the manufacture of a three-dimensional lamination-shaped mold, this invention provides a granular material for use in shaping a three-dimensional laminated mold, which is coated with an acid as a catalyst which activates and cures an organic binder for binding the granular material. The acid contains at least one of sulfuric acid, phosphoric acid, a sulfonic acid and a carboxylic acid, and is one of a mixture of sulfuric acid and another acid, phosphoric acid only, a mixture of phosphoric acid and another acid, sulfonic acid only, a mixture of sulfonic acid and another acid and a mixture of a carboxylic acid and another acid.

Abstract: The communication system has a plurality of sub-networks, for example composed of transmission communication nodes, PBX communication notes, application communication nodes, and the like, respectively. Each of these sub-networks is managed by a management system, and all of the management systems are managed by an integrated management system. Each communication node is autonomously provided with the function of establishing an emergency routing as a first stage routing control on the occurrence of a failure in a circuit affecting the communication node. The autonomous routing is heirarchial with respect to node types. Failure and the influences of failure are reported to the sub-network management systems, which in turn can report to the integrated management system. As a second stage of routing control, one or more of the management systems establishes a global routing to replace the emergency local routing.

Abstract: There are disclosed flux cored wire electrodes for self-shielded arc welding which comprise a steel sheath filled with a powdery flux containing as essential components thereof the following components set forth in terms of weight percentage: BaF.sub.2 (25-70), alkali metal fluoride (1-30), compound oxide composed of the oxide of an alkaline earth metal selected from among Ca, Sr, and Ba and the oxide of a metal selected from among Fe, Mn, Ni, Co, Ti, Al and Zr (1-30), Al (3-12), Mg (2-10) and Mn (0.5-10).

Abstract: A flux-cored welding electrode for gas-shielded arc welding comprising a mild steel sheath and a flux core, said flux core having the following composition based on the total weight of the electrode:TiO.sub.2 -4 to 8.5%Mg-0.2 to 0.8%Ti-0.03 to 0.7%B-0.002 to 0.025%Mn-1.0 to 3.0%Si-0.01 to 1.2%Metal fluorides-0.1 to 0.30% as F-contentOxides-not more than 8.5%, including TiO.sub.2.

Abstract: An arc welding process using a consumable stranded wire electrode which is formed either by integrally intertwisting a plurality of wire elements substantially of the same sectional area such that the lines connecting center points of adjacent wire elements do not form a regular polygon in a sectional plane or by integrally intertwisting a plurality of wire elements of different sectional areas such that the lines connecting center points of wire elements of larger diameter do not form a regular polygon in a sectional plane wherein the consumable electrode is imparted with a bending trait and contacted with a surface on the inner periphery and at the outlet end of a conducting tip, and the arc is directed toward a center weld line to thereby obtain a stable arc.

Abstract: The present invention relates to a method of vertically upward arc welding for vertical and inclined joints. More particularly, the invention relates to a vertically upward arc welding method which includes the step of feeding a strip electrode in a direction at which the plane including the width direction of the strip electrode crosses the weld line, generating an arc from the strip electrode to a molten pool and/or an upper base metal disposed above the surface of the molten pool, melting the upper base metal disposed above a sliding backing shoe on the front surface side of the groove, and performing welding by expanding the groove and simultaneously dropping the molten metal onto the lower molten pool and depositing the same therein.

Abstract: An arc welding process having a welding arc generated between a consumable electrode and the materials to be welded and a welding torch is oscillated along the welding joint line, wherein the arc length is longer when the welding torch is located at the forward side of the oscillation than when the welding torch is located at the backward side of the oscillation with respect to the weld advancing direction, whereby sufficient penetration is obtained.