Patents by Inventor Yasuhiro Nojima

Yasuhiro Nojima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8673839
    Abstract: A biologically active complex of lactoferrin with a branched non-peptide hydrophilic polymer, one example of which is represented by the following formula [1]: LF-[X-Lp-R—(Yp-POLY)q]n??[I] Wherein LF is lactoferrin, X is a linkage generated by reaction of functional groups, L is a linker, R is an aliphatic hydrocarbon group having at least 3 carbon atoms, Y is a heteroatom linkage, POLY is a non-peptide hydrophilic polymer, p is 0 or 1, q is an integer of 2 to 10, and n is an integer of 1 to 10.
    Type: Grant
    Filed: August 22, 2006
    Date of Patent: March 18, 2014
    Assignee: NRL Pharma, Inc.
    Inventors: Yasuhiro Nojima, Atsushi Sato
  • Publication number: 20090281029
    Abstract: A biologically active complex of lactoferrin with a branched non-peptide hydrophilic polymer, one example of which is represented by the following formula [I]: LF-[X-Lp-R—(Yp-POLY)q]n ??[I] Wherein LF is lactoferrin, X is a linkage generated by reaction of functional groups, L is a linker, R is an aliphatic hydrocarbon group having at least 3 carbon atoms, Y is a heteroatom linkage, POLY is a non-peptide hydrophilic polymer, p is 0 or 1, q is an integer of 2 to 10, and n is an integer of 1 to 10.
    Type: Application
    Filed: August 22, 2006
    Publication date: November 12, 2009
    Applicant: NRL PHARMA, INC.
    Inventors: Yasuhiro Nojima, Atsushi Sato
  • Patent number: 4849482
    Abstract: The present invention provides a process for producing vinyl chloride resin in suspension polymerization of vinyl chloride monomer by the use of a polymerization reactor equipped with a reflux condenser using an improved brumagine-type impeller equipped with auxiliary blade/s, and polymerization is started in a range of 0.8 to 1.0 of the water/monomer ratio, polymerization temperature is raised to 3.degree. to 10.degree. C. at polymer conversion being not more than 50 weight percent, with water being added in the course of polymerization not more than making up for the volumetrical contraction resulting from the progress of polymerization so that upon completion of polymerization the water/monomer ratio is controlled in a range of 1.0 to 1.4. The polyvinyl chloride resin obtained by the present process is superior in quality such as high bulk density and little fish eye with high productivity.
    Type: Grant
    Filed: June 30, 1987
    Date of Patent: July 18, 1989
    Assignee: Kanegafuchi Kagaki Kogyo Kabushiki Kaisha
    Inventors: Teiji Kobayashi, Yoshio Tomishima, Taizo Yamamoto, Yasuhiro Nojima
  • Patent number: 4771114
    Abstract: The present invention provides a process for producing vinyl chloride resin in suspension polymerization of vinyl chloride monomer by the use of a polymerization reactor equipped with a reflux condenser wherein a nonionic surface active agent having a HLB value of 6-14 is added upon initial charging of reactants, polymerization is started in a range of 0.8 to 1.0 of the water/monomer ratio, the polymerization temperature is raised 3.degree. to 10.degree. C. when polymer conversion is not more the 50 weight percent, with water being added in the course of polymerization to not more than make up for the volumetrical contraction resulting from the progress of polymerization so that upon completion of polymerization the water/monomer ratio is controlled in a range of 1.0 to 1.4. The polyvinyl chloride resin obtained by the present process is superior in quality such as high bulk density and little fish eye content with high productivity.
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: September 13, 1988
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Teiji Kobayashi, Yoshio Tomishima, Taizo Yamamoto, Yasuhiro Nojima
  • Patent number: 4555555
    Abstract: A process for polymerizing vinyl chloride is disclosed which comprises coating prior to the polymerization the surfaces of a polymerization reactor, agitator blades and a reflux condenser with a reaction product obtained by the reaction of a phenolic compound and an aromatic aldehyde, said reaction product having an average molecular weight of from 3,000 to 10,000. Not only is the polymer scales formation prevented surprisingly, but a high quality product substantially free from fish eyes is obtained.
    Type: Grant
    Filed: January 17, 1984
    Date of Patent: November 26, 1985
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Eietsu Toyooka, Yoshio Tomishima, Yasuhiro Nojima
  • Patent number: 4455413
    Abstract: A method for production of vinyl chloride resin is provided, in which vinyl chloride or a monomeric mixture containing vinyl chloride as a major ingredient is polymerized, while controlling the operation of a reflux condenser provided at a polymerization vessel by supplying hot water or steam and then cooling water to the side of cooling water of the condenser, whereby bubbling is suppressed. The method provides outstanding advantages, such as, a high quality product improved with respect to fish eyes, high productivity, a shortened polymerization time, and a savings in steam for heating.
    Type: Grant
    Filed: June 22, 1982
    Date of Patent: June 19, 1984
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Yoshio Tomishima, Teiji Kobayashi, Hiroshi Shibahara, Yasuhiro Nojima