Patents by Inventor Yasuhiro Takeji

Yasuhiro Takeji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyanopyrimidine derivative
    Patent number: 9708292
    Abstract: The present invention relates to a novel cyanopyrimidine compound and a pharmaceutical composition which have a safe and potent adenosine A2a receptor agonistic activity.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: July 18, 2017
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Norifumi Sato, Yohei Yuki, Hisashi Shinohara, Yasuhiro Takeji, Kuni Ito, Daisaku Michikami, Keisuke Hino, Hiroyuki Yamazaki
  • MEDICAMENT FOR TREATING ANTERIOR EYE DISEASE COMPRISING REBAMIPIDE AND A TEAR-RETAINING AGENT
    Publication number: 20140294991
    Abstract: The present invention provides a combination of rebamipide and a tear-retaining agent as a medicament for the treatment of anterior eye diseases.
    Type: Application
    Filed: October 31, 2012
    Publication date: October 2, 2014
    Inventors: Yasuhiro Takeji, Hideo Nakashima, Hiroki Urashima, Hisashi Shinohara, Yuki Hirata
  • NOVEL CYANOPYRIMIDINE DERIVATIVE
    Publication number: 20120022077
    Abstract: The present invention relates to a novel cyanopyrimidine compound and a pharmaceutical composition which have a safe and potent adenosine A2a receptor agonistic activity.
    Type: Application
    Filed: February 2, 2010
    Publication date: January 26, 2012
    Inventors: Norifumi Sato, Yohei Yuki, Hisashi Shinohara, Yasuhiro Takeji, Kuni Ito, Daisaku Michikami, Keisuke Hino, Hiroyuki Yamazaki
  • 4-amino 5-cyanopyrimidine derivatives
    Patent number: 7989446
    Abstract: The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: August 2, 2011
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Masaya Kato, Norifumi Sato, Minoru Okada, Tetsuyuki Uno, Nobuaki Ito, Yasuhiro Takeji, Hisashi Shinohara, Masahiro Fuwa
  • 4-Amino-5-cyanopyrimidine derivatives
    Publication number: 20110009620
    Abstract: The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
    Type: Application
    Filed: September 22, 2010
    Publication date: January 13, 2011
    Inventors: Masaya Kato, Norifumi Sato, Minoru Okada, Tetsuyuki Uno, Nobuaki Ito, Yasuhiro Takeji, Hisashi Shinohara, Masahiro Fuwa
  • 4-amino-5-cyanopyrimidine derivatives
    Patent number: 7834002
    Abstract: The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: November 16, 2010
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Masaya Kato, Norifumi Sato, Minoru Okada, Tetsuyuki Uno, Nobuaki Ito, Yasuhiro Takeji, Hisashi Shinohara, Masahiro Fuwa
  • 4-Amino-5-Cyanopyrimidine Derivatives
    Publication number: 20080182854
    Abstract: The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
    Type: Application
    Filed: April 28, 2005
    Publication date: July 31, 2008
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaya Kato, Norifumi Sato, Minoru Okada, Tetsuyuki Uno, Nobuaki Ito, Yasuhiro Takeji, Hisashi Shinohara, Masahiro Fuwa
  • Carbostyril derivative for curing ophthalmological diseases
    Patent number: 6060486
    Abstract: The present invention provides an agent for curing ophthalmological diseases which contains, as the active ingredient, a carbostyril derivative or salt thereof represented by the general formula (I), ##STR1## (wherein R is a halogen atom) particularly, the invention provides effective agent for curing xerophalmia (dry eye) syndrome.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: May 9, 2000
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiroki Urashima, Yasuhiro Takeji, Hisashi Shinohara, Shigeki Fujisawa