Abstract: A fishing rod includes a hollow rod extending along a central axis; and a shaft member with an outer peripheral surface inclined relative to the central axis inserted into the rod from the one end, and that is supported by an inner peripheral surface of the rod at a support position on another end side of the one end in an axial direction along the central axis, wherein the inner peripheral surface of the rod has at least one convex portion protruding toward the central axis from a virtual curve between the support position and the one end position axially when drawing a virtual curve that is convex toward the central axis through the support position and the one end position at the end of the end side of the inner peripheral surface in an area radially outward from the outer peripheral surface of the shaft member.

Abstract: A fishing rod according to one embodiment of the invention includes a small-diameter hollow rod body extending in a central axis direction, a large-diameter hollow rod body extending in the central axis direction, and a spigot ferrule inserted in the small-diameter rod body from its rear end and into the large-diameter rod body from its front end to connect the small-diameter rod body and the large-diameter rod body. In the fishing rod, a first inclined surface that extends from an rear end of the small-diameter rod body at an angle of 0.1° to 10.0° with respect to the central axis direction is formed on an inner peripheral surface of the small-diameter rod body.

Abstract: A fishing rod includes a hollow rod extending along a central axis; and a shaft member with an outer peripheral surface inclined relative to the central axis inserted into the rod from the one end, and that is supported by an inner peripheral surface of the rod at a support position on another end side of the one end in an axial direction along the central axis, wherein the inner peripheral surface of the rod has at least one convex portion protruding toward the central axis from a virtual curve between the support position and the one end position axially when drawing a virtual curve that is convex toward the central axis through the support position and the one end position at the end of the end side of the inner peripheral surface in an area radially outward from the outer peripheral surface of the shaft member.

Abstract: The present disclosure provides a composition and a method both for improving the hair. In one embodiment, the hair is improved using an antibody. In one embodiment, the antibody is produced using a bacterium occurring on the scalp or a hair root as an immunogen. In one aspect, the present invention also provides a method for improving the hair in a subject, including the step of administering an antibody produced using a microorganism-derived substance as an immunogen to the subject. The antibody according to the present invention may be administered in the form of a composition. According to the present invention, the promotion of hair growth or the prevention of hair loss can be achieved.

Abstract: One object is to provide a fishing line guide including a high-hardness guide ring and a fishing rod provided with said fishing line guide. A fishing line guide according to one embodiment of the present invention includes a guide body with a through hole formed therein and a guide ring fitted into the through hole of the guide body. In one aspect, the guide ring includes a base material layer and a surface layer formed on a surface of the base material layer. In one aspect of the present invention, the base material layer is formed of an alloy having an Fe content of 3 wt % or less or 2 wt % or less. In one aspect of the present invention, the surface layer is formed of chromium carbide, titanium carbide, or vanadium carbide.

Abstract: For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Abstract: A fishing rod according to one embodiment of the invention includes a small-diameter hollow rod body extending in a central axis direction, a large-diameter hollow rod body extending in the central axis direction, and a spigot ferrule inserted in the small-diameter rod body from its rear end and into the large-diameter rod body from its front end to connect the small-diameter rod body and the large-diameter rod body. In the fishing rod, a first inclined surface that extends from an rear end of the small-diameter rod body at an angle of 0.1° to 10.0° with respect to the central axis direction is formed on an inner peripheral surface of the small-diameter rod body.

Abstract: The present invention provides an ostrich antibody-containing composition for treating a bacterial infectious disease, and a method for treating a bacterial infectious disease by using the ostrich antibody. The present invention further provides a method for producing this ostrich antibody. The infectious disease can be a gastrointestinal infection. The ostrich antibody can be produced by using a component derived from a bacterium as an immunogen. The bacterium can be Clostridium difficile, Vibrio cholera, Staphylococcus aureus, or the like. Further, the bacterium can be a drug-resistant bacterium.

Abstract: There are many reports of diseases caused by overeating, satiation, and an unbalanced diet, and various therapeutic methods and therapeutic drugs are proposed for said diseases. There have not been many proposals, for prevention of these diseases, of methods by which what is eaten is not readily absorbed in vivo. The present invention involves inoculating female birds with a digestive enzyme as an antigen, said digestive enzyme being present in vivo. As a result of inhibiting the activity of the digestive enzyme by using an antibody which has been produced in vivo in the birds, the present invention inhibits decomposition of proteins, lipids, and carbohydrates and reduces in vivo absorption. This type of antibody can be obtained from an egg laid by a female bird which has received the antigen, and furthermore the egg itself includes the antibody. Consequently, a food product that contains, as an ingredient thereof, eggs having this type of antibody is low in proteins, lipids, and carbohydrates.

Abstract: For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Abstract: For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substancesa released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Abstract: Causes of hair loss have not been completely clarified and still remain unknown in many points. However, it appears that hair loss is partly caused by a mechanism wherein androgenic hormones in the scalp become active via the activation of DHT hormone by 5?-reductase and thus the activity of cells in hair roots is lost. In the present invention, an antibody, said antibody being obtained by inoculating a female bird with 5?-reductase or DHT as an antigen, is administered to the scalp so that the activity of DHT is suppressed and the activity of cells in hair roots is elevated. This antibody can be used in the form of a composition together with other component(s), for example, as a hair tonic together with another hair growth promoter.

Abstract: One object is to provide a fishing line guide including a high-hardness guide ring and a fishing rod provided with said fishing line guide. A fishing line guide according to one embodiment of the present invention includes a guide body with a through hole formed therein and a guide ring fitted into the through hole of the guide body. In one aspect, the guide ring includes a base material layer and a surface layer formed on a surface of the base material layer. In one aspect of the present invention, the base material layer is formed of an alloy having an Fe content of 3 wt % or less or 2 wt % or less. In one aspect of the present invention, the surface layer is formed of chromium carbide, titanium carbide, or vanadium carbide.

Abstract: For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Abstract: There are many reports of diseases caused by overeating, satiation, and an unbalanced diet, and various therapeutic methods and therapeutic drugs are proposed for said diseases. There have not been many proposals, for prevention of these diseases, of methods by which what is eaten is not readily absorbed in vivo. The present invention involves inoculating female birds with a digestive enzyme as an antigen, said digestive enzyme being present in vivo. As a result of inhibiting the activity of the digestive enzyme by using an antibody which has been produced in vivo in the birds, the present invention inhibits decomposition of proteins, lipids, and carbohydrates and reduces in vivo absorption. This type of antibody can be obtained from an egg laid by a female bird which has received the antigen, and furthermore the egg itself includes the antibody. Consequently, a food product that contains, as an ingredient thereof, eggs having this type of antibody is low in proteins, lipids, and carbohydrates.

Abstract: For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Abstract: Causes of hair loss have not been completely clarified and still remain unknown in many points. However, it appears that hair loss is partly caused by a mechanism wherein androgenic hormones in the scalp become active via the activation of DHT hormone by 5?-reductase and thus the activity of cells in hair roots is lost. In the present invention, an antibody, said antibody being obtained by inoculating a female bird with 5?-reductase or DHT as an antigen, is administered to the scalp so that the activity of DHT is suppressed and the activity of cells in hair roots is elevated. This antibody can be used in the form of a composition together with other component (s), for example, as a hair tonic together with another hair growth promoter.

Abstract: There are many reports of diseases caused by overeating, satiation, and an unbalanced diet, and various therapeutic methods and therapeutic drugs are proposed for said diseases. There have not been many proposals, for prevention of these diseases, of methods by which what is eaten is not readily absorbed in vivo. The present invention involves inoculating female birds with a digestive enzyme as an antigen, said digestive enzyme being present in vivo. As a result of inhibiting the activity of the digestive enzyme by using an antibody which has been produced in vivo in the birds, the present invention inhibits decomposition of proteins, lipids, and carbohydrates and reduces in vivo absorption. This type of antibody can be obtained from an egg laid by a female bird which has received the antigen, and furthermore the egg itself includes the antibody. Consequently, a food product that contains, as an ingredient thereof, eggs having this type of antibody is low in proteins, lipids, and carbohydrates.

Abstract: Causes of hair loss have not been completely clarified and still remain unknown in many points. However, it appears that hair loss is partly caused by a mechanism wherein androgenic hormones in the scalp become active via the activation of DHT hormone by 5?-reductase and thus the activity of cells in hair roots is lost. In the present invention, an antibody, said antibody being obtained by inoculating a female bird with 5?-reductase or DHT as an antigen, is administered to the scalp so that the activity of DHT is suppressed and the activity of cells in hair roots is elevated. This antibody can be used in the form of a composition together with other component(s), for example, as a hair tonic together with another hair growth promoter.

Abstract: For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.