Abstract: A microchip including a fluid circuit formed by a groove of a first substrate and a surface of a second substrate is provided. The fluid circuit includes a fluid retaining reservoir for containing a fluid. The fluid retaining reservoir includes a fluid outlet or outflow channel for allowing the fluid to flow out, and a partition dividing the fluid retaining reservoir into a first region including a fluid inlet for injecting a fluid into the fluid retaining reservoir and a second region including the fluid outlet or outflow channel. The partition includes at least one communication gate for allowing communication between the first region and the second region.

Abstract: A microchip including a fluid circuit formed by a groove of a first substrate and a surface of a second substrate is provided. The fluid circuit includes a fluid retaining reservoir for containing a fluid. The fluid retaining reservoir includes a fluid outlet or outflow channel for allowing the fluid to flow out, and a partition dividing the fluid retaining reservoir into a first region including a fluid inlet for injecting a fluid into the fluid retaining reservoir and a second region including the fluid outlet or outflow channel. The partition includes at least one communication gate for allowing communication between the first region and the second region.

Abstract: A microchip including a fluid circuit formed by a groove of a first substrate and a surface of a second substrate is provided. The fluid circuit includes a fluid retaining reservoir for containing a fluid. The fluid retaining reservoir includes a fluid outlet or outflow channel for allowing the fluid to flow out, and a partition dividing the fluid retaining reservoir into a first region including a fluid inlet for injecting a fluid into the fluid retaining reservoir and a second region including the fluid outlet or outflow channel. The partition includes at least one communication gate for allowing communication between the first region and the second region.

Abstract: The present invention provides a microchip which is made by bonding a first substrate having a groove provided at the substrate surface and a second substrate together, and has a fluid circuit therein, the fluid circuit having a separation portion for separating a first component, and a groove which constitutes the separation portion including an approximately V-shaped region surrounded by prescribed flow channel walls. At a top of the separation portion, a flow rate limiting portion limiting a flow rate of a fluid is preferably provided.

Abstract: The present invention provides a microchip which is made by bonding a first substrate having a groove provided at the substrate surface and a second substrate together, and has a fluid circuit therein, the fluid circuit having a separation portion for separating a first component, and a groove which constitutes the separation portion including an approximately V-shaped region surrounded by prescribed flow channel walls. At a top of the separation portion, a flow rate limiting portion limiting a flow rate of a fluid is preferably provided.

Abstract: There is provided a microchip that is formed of a first substrate having a surface with a groove and a second substrate joined together and has a fluid circuit in the form of a cavity defined by the groove and a surface of the second substrate closer to the first substrate. The fluid circuit at least includes a detection portion having an optical path for transmitting light. The microchip includes at least one of a step defined by a groove formed in contact with at least one side surface of a groove of the first substrate that defines the optical path and a recess provided in the second substrate at a position opposite to the step.

Abstract: The capture rate of a target such as antigen and antibody in a sample is improved and the concentration of reaction product of a recognition substance is uniformized regardless of the position of a reaction field. By contacting microparticles and the sample using centrifugal force, the contact time of the target and the recognition substance is equalized regardless of the position in mixing chamber The microparticles and the sample are mixed evenly in the mixing chamber by changing the rotation direction and the concentration of reactant in a liquid mixture is uniform regardless of the position of the mixing chamber. When the liquid mixture having a uniform concentration is obtained, it is enough to extract a part of the liquid mixture and use the same for a process subsequent to a mixing process without the need of using all the liquid mixture.

Abstract: A microchip including a fluid circuit formed by a groove of a first substrate and a surface of a second substrate is provided. The fluid circuit includes a fluid retaining reservoir for containing a fluid. The fluid retaining reservoir includes a fluid outlet or outflow channel for allowing the fluid to flow out, and a partition dividing the fluid retaining reservoir into a first region including a fluid inlet for injecting a fluid into the fluid retaining reservoir and a second region including the fluid outlet or outflow channel. The partition includes at least one communication gate for allowing communication between the first region and the second region.

Abstract: The present invention provides a microchip which is made by bonding a first substrate having a groove provided at the substrate surface and a second substrate together, and has a fluid circuit therein, the fluid circuit having a separation portion for separating a first component, and a groove which constitutes the separation portion including an approximately V-shaped region surrounded by prescribed flow channel walls. At a top of the separation portion, a flow rate limiting portion limiting a flow rate of a fluid is preferably provided.

Abstract: There is provided a microchip that is formed of a first substrate having a surface with a groove and a second substrate joined together and has a fluid circuit in the form of a cavity defined by the groove and a surface of the second substrate closer to the first substrate. The fluid circuit at least includes a detection portion having an optical path for transmitting light. The microchip includes at least one of a step defined by a groove formed in contact with at least one side surface of a groove of the first substrate that defines the optical path and a recess provided in the second substrate at a position opposite to the step.

Abstract: A microfluidic chip used in latex agglutination for analyzing a small amount of liquid specimen with a latex reagent is provided, in order to suppress adsorption of latex particles into an inner wall surface of a latex reagent retaining chamber of the microfluidic chip, and to improve measuring precision of the latex agglutination. The microfluidic chip includes a retaining chamber for the latex reagent, wherein an absolute value of a surface zeta potential in at least one inner wall surface of the retaining chamber is at least 20 mV.