Patents by Inventor Yasuhisa Takeda

Yasuhisa Takeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methotrexate derivative
    Patent number: 5354753
    Abstract: Disclosed is a compound represented by the formula: ##STR1## wherein R.sup.1 : CH.sub.2, CH.sub.2 CH.sub.2, CH.sub.2 O, CH.sub.2 S, CH.sub.2 SO; R.sup.2 : hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms or a benzyl group; n: an integer of 1 to 4; R.sup.3 : COOR.sup.4, NHCOR.sup.5, CONR.sup.6 R.sup.7, PO.sub.3 H.sub.2, SO.sub.3 H.The compound shows potent antirheumatic function, psoriasis curing function and carcinostatic function and has low toxicity whereby it is available as a medicine.
    Type: Grant
    Filed: February 12, 1993
    Date of Patent: October 11, 1994
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Nobuhiro Ohi, Hiroharu Matsuoka, Katushito Miyamoto, Hiroshi Suzuki, Nobuaki Kato, Keiichiro Tsuji, Yasuhisa Takeda, Masahiko Mihara, Hiromichi Nishina, Shin Shimaoka, Kenichi Akamatsu
  • Tetrahydronicotinamide derivative, pharmaceutical compositions and use
    Patent number: 4361572
    Abstract: 1,4,5,6-Tetrahydronicotinamide derivative represented by the formula: ##STR1## (wherein R is defined in the specification), a process of preparing the same and pharmaceutical composition containing the same are disclosed.The compound has action for suppressing aggregation of platelets, and antiinflammatory, antipyretic and analgesic actions.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: November 30, 1982
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Sakae Takaku, Fumiaki Matsuura, Takashi Mori, Yasushi Murakami, Shigeyuki Kataoka, Yasuhisa Takeda, Yasuhiro Yamashita, Yumiko Takeda, Takashi Matsuno, Koji Mizuno, Shinichi Kaiho, Tamotsu Yamazaki, Shun-ichi Hata, Shigeru Takanashi
  • Anti-tumor preparation against certain tumors and process for preparing the same
    Patent number: 4349541
    Abstract: An anti-tumor preparation containing cells of Streptococcus equisimilis and a process for preparing the preparation which comprises subjecting the cells to heat treatment in a salt solution with or without penicillin treatment.
    Type: Grant
    Filed: May 25, 1979
    Date of Patent: September 14, 1982
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yasuhisa Takeda, Takashi Matsuno, Mihoko Ohtaka, Hiroki Mitsui, Tsutomu Kawaguchi, Hisako Masuda, Hiroshi Okazaki, Mitsuaki Handa, Yutaka Sugawara, Haruki Ogawa
  • Terephthalic acid monoamide derivatives, process for preparing the same, and an anti-allergic agent prepared from the same
    Patent number: 4221814
    Abstract: A terephthalic acid monoamide derivative of the formula: ##STR1## (wherein R is a straight- or branched-chain lower alkyl group; R' and R" may be the same or different, and represent a hydrogen atom, or a straight- or branched-chain lower alkyl group) or pharmaceutically acceptable salts thereof are disclosed. A process for preparing such terephthalic acid monoamide derivative or its salts, as well as an anti-allergic agent containing such derivative or its salts as an effective ingredient are also disclosed.
    Type: Grant
    Filed: June 1, 1979
    Date of Patent: September 9, 1980
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Sakae Takaku, Takashi Mori, Yasushi Murakami, Yoshiyuki Ohsugi, Shigeyuki Kataoka, Yasuhisa Takeda, Takashi Matsuno, Yoshimitsu Iida, Akiko Ariga, Akira Okazaki, Kazuo Igusa, Toshichika Ogasawara, Minoru Shindo