Patents by Inventor Yasumitsu Okouchi

Yasumitsu Okouchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing tissues for vitrification
    Publication number: 20010031459
    Abstract: The invention relates to the field of organ and tissue perfusion. More particularly, the present invention relates to a method for preparing organs, such as the kidney and liver, for cryopreservation through the introduction of vitrifiable concentrations of cryoprotectant into them. To prepare the organ for cryopreservation, the donor human or animal, is treated in the usual manner and may also be treated with iloprost, or other vasodilators, and/or transforming growth factor &bgr;1. Alternatively, or additionally, the organ which is to be cryopreserved can be administered iloprost, or other vasodilators, and/or transforming growth factor &bgr;1 directly into its artery. The invention also relates to preparing organs for transplantation by a method for the removal of the cryoprotectant therefrom using low (such as raffinose, sucrose, mannitol, etc.
    Type: Application
    Filed: January 12, 2001
    Publication date: October 18, 2001
    Applicant: THE AMERICAN NATIONAL RED CROSS
    Inventors: Gregory Fahy, Bijan Khirabadi, Yasumitsu Okouchi, Thomas Maciag
  • Method for preparing organs for transplantation after cryopreservation
    Patent number: 6187529
    Abstract: The invention relates to the field of organ and tissue perfusion. More particularly, the present invention relates to a method for preparing organs, such as the kidney and liver, for cryopreservation through the introduction of vitrifiable concentrations of cryoprotectant into them. To prepare the organ for cryopreservation, the donor human or animal, is treated in the usual manner and may also be treated with iloprost, or other vasodilators, and/or transforming growth factor &bgr;1. Alternatively, or additionally, the organ which is to be cryopreserved can be administered iloprost, or other vasodilators, and/or transforming growth factor &bgr;1 directly into its artery. The invention also relates to preparing organs for transplantation by a method for the removal of the cryoprotectant therefrom using low (such as raffinose, sucrose, mannitol, etc.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: February 13, 2001
    Assignee: The American National Red Cross
    Inventors: Gregory M. Fahy, Bijan Khirabadi, Yasumitsu Okouchi, Thomas Maciag
  • Method of preparing tissues and cells for vitrification
    Patent number: 5962214
    Abstract: The invention relates to the field of organ and tissue perfusion. More particularly, the present invention relates to a method for preparing organs, such as the kidney and liver, for cryopreservation through the introduction of vitrifiable concentrations of cryoprotectant into them. To prepare the organ for cryopreservation, the donor human or animal, is treated in the usual manner and may also be treated with iloprost, or other vasodilators, and/or transforming growth factor .beta.1. Alternatively, or additionally, the organ which is to be cryopreserved can be administered iloprost, or other vasodilators, and/or transforming growth factor .beta.1 directly into its artery. The invention also relates to preparing organs for transplantation by a method for the removal of the cryoprotectant therefrom using low (such as raffi nose, sucrose, mannitol, etc.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: October 5, 1999
    Assignee: The United States of America as represented by The American National Red Cross
    Inventors: Gregory M. Fahy, Bijan Khirabadi, Yasumitsu Okouchi, Thomas Maciag
  • Methods for removal of cryoprotectant from organs prior to transplantation
    Patent number: 5821045
    Abstract: The invention relates to the field of organ and tissue perfusion. More particularly, the present invention relates to a method for preparing organs, such as the kidney and liver, for cryopreservation through the introduction of vitrifiable concentrations of cryoprotectant into them. To prepare the organ for cryopreservation, the donor human or animal, is treated in the usual manner and may also be treated with iloprost, or other vasodilators, and/or transforming growth factor .beta.1. Alternatively, or additionally, the organ which is to be cryopreserved can be administered iloprost, or other vasodilators, and/or transforming growth factor .beta.1 directly into its artery. The invention also relates to preparing organs for transplantation by a method for the removal of the cryoprotectant therefrom using low (such as raffinose, sucrose, mannitol, etc.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 13, 1998
    Assignee: The American National Red Cross
    Inventors: Gregory M. Fahy, Bijan Khirabadi, Yasumitsu Okouchi
  • Method of preparing organs for vitrification
    Patent number: 5723282
    Abstract: The invention relates to the field of organ and tissue perfusion. More particularly, the present invention relates to a method for preparing organs, such as the kidney and liver, for cryopreservation through the introduction of vitrifiable concentrations of cryoprotectant into them. To prepare the organ for cryopreservation, the donor human or animal, is treated in the usual manner and may also be treated with iloprost, or other vasodilators, and/or transforming growth factor .beta.1. Alternatively, or additionally, the organ which is to be cryopreserved can be administered iloprost, or other vasodilators, and/or transforming growth factor .beta.1 directly into its artery. The invention also relates to preparing organs for transplantation by a method for the removal of the cryoprotectant therefrom using low (such as raffinose, sucrose, mannitol, etc.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: March 3, 1998
    Assignee: The American National Red Cross
    Inventors: Gregory M. Fahy, Bijan Khirabadi, Yasumitsu Okouchi, Thomas Maciag