Patents by Inventor Yasumitsu Tamura

Yasumitsu Tamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5238938
    Abstract: The novel indole derivatives and salts thereof represented by the general formula (1) ##STR1## possess, for example, an inhibitory effect against superoxide (O.sub.2.sup.-) released from the macrophage cells of guinea pig by stimulation and an anti-albuminuria activity against Masugi nephritis, and are useful in various clinical fields as an agent for preventing and treating diseases and cases associated with the above superoxide radical, for example, autoimmune diseases (e.g. rheumatism), arteriosclerosis, ischemic disease, ischemic encephalopathia, hepatic insufficiency and renal insufficiency, and also as an agent for preventing and treating nephritis.
    Type: Grant
    Filed: March 26, 1992
    Date of Patent: August 24, 1993
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hitoshi Tone, Seiji Sato, Hideaki Sato, Katsumi Tamura, Shigeharu Tamada, Kazumi Kondo, Tomoyuki Kawaguchi, Yoshimasa Nakano, Yasuyuki Kita, Shuji Akai, Hiromichi Fujioka, Yasumitsu Tamura, Katsuhide Matoba, Youichi Taniguchi, Shinji Nishitani, Satoshi Hayakawa, Toshinori Kaneyasu, Yoshihiko Ito, Masahiro Murakami
  • Patent number: 5191074
    Abstract: A process for producing a .beta.-lactam compound of the formula ##STR1## wherein OR.sup.1 is a protected or unprotected hydroxyl group; R.sup.2 is a C.sub.1 to C.sub.7 alkyl or aryl group; from an azetidinone compound of the formula ##STR2## wherein X is an electronegative group removable through the reaction in three steps in which the second step subjects the .beta.-lactam compound obtained in the first step to silylation to convert the R.sup.2 group to the beta form.
    Type: Grant
    Filed: August 12, 1991
    Date of Patent: March 2, 1993
    Assignees: Yasumitsu Tamura, Shionogi & Co., Ltd.
    Inventors: Yasumitsu Tamura, Junichi Haruta, Nishi Koichi
  • Patent number: 4745209
    Abstract: Alpha-arylalkanoic esters are prepared by reacting a trivalent iodine compound represented by the general formula:Ar--I.dbd.Owherein Ar is an aromatic hydrocarbon, group, with a carbonyl compound represented by the general formula ##STR1## wherein Ar.sup.1 is an aromatic hydrocarbon, R is a hydrogen atom or an alkyl group and R.sup.1 is a hydrogen atom or an alkyl group, in the presence of an orthocarboxylic ester.
    Type: Grant
    Filed: March 13, 1986
    Date of Patent: May 17, 1988
    Assignee: Yasumitsu Tamura
    Inventors: Yasumitsu Tamura, Junichi Haruta