Patents by Inventor Yasumoto Matsumura

Yasumoto Matsumura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biodegradable, Antioxidant, Thermally Responsive Injectable Hydrogel and Uses Therefor
    Publication number: 20230149442
    Abstract: Provided herein are antioxidant, thermally-responsive polymeric compositions and methods of making and using the compositions, e.g., for treatment of ischemia reperfusion injury or radiation exposure.
    Type: Application
    Filed: January 18, 2023
    Publication date: May 18, 2023
    Inventors: William R. Wagner, Yasumoto Matsumura, Murugesan Velayutham, Yang Zhu
  • Biodegradable, antioxidant, thermally responsive injectable hydrogel and uses therefor
    Patent number: 11590162
    Abstract: Provided herein are antioxidant, thermally-responsive copolymer-based compositions and methods of making and using the compositions, e.g., for treatment of ischemia reperfusion injury in a patient. The copolymer comprises a hydrocarbyl backbone, and a plurality of pendant pyrrolidone, antioxidant radical, polyester oligomer, and N-alkyl amide groups.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: February 28, 2023
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: William R. Wagner, Yasumoto Matsumura, Murugesan Velayutham, Yang Zhu
  • Stentless Biopolymer Heart Valve Replacement Capable of Living Tissue Regeneration
    Publication number: 20220249226
    Abstract: A template for a valve construct for replacement of at least one of a mitral valve and a tricuspid valve includes at least an anterior leaflet portion and at least a posterior leaflet portion, each leaflet portion having a proximal edge, a distal edge, and side edges extending between the proximal edge and the distal edge. The template further includes a plurality of substantially straight elongated chordae portions each having a proximal end connected to the distal edge of one of the at least two leaflet portions and a distal end extending therefrom and one or more papillary muscle head portions formed at a commissure between distal ends of at least two of the plurality of chordae portions. A total width of the leaflet portions of the template is substantially equal to a circumference of a native annulus of a heart valve.
    Type: Application
    Filed: April 27, 2022
    Publication date: August 11, 2022
    Inventors: Vinay Badhwar, Antonio D'Amore, Yasumoto Matsumura, William R. Wagner
  • Stentless biopolymer heart valve replacement capable of living tissue regeneration
    Patent number: 11337799
    Abstract: A template for a valve construct for replacement of at least one of a mitral valve and a tricuspid valve includes at least an anterior leaflet portion and at least a posterior leaflet portion, each leaflet portion having a proximal edge, a distal edge, and side edges extending between the proximal edge and the distal edge. The template further includes a plurality of substantially straight elongated chordae portions each having a proximal end connected to the distal edge of one of the at least two leaflet portions and a distal end extending therefrom and one or more papillary muscle head portions formed at a commissure between distal ends of at least two of the plurality of chordae portions. A total width of the leaflet portions of the template is substantially equal to a circumference of a native annulus of a heart valve.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: May 24, 2022
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Vinay Badhwar, Antonio D'Amore, Yasumoto Matsumura, William R. Wagner
  • Stentless Biopolymer Heart Valve Replacement Capable of Living Tissue Regeneration
    Publication number: 20200054448
    Abstract: A template for a valve construct for replacement of at least one of a mitral valve and a tricuspid valve includes at least an anterior leaflet portion and at least a posterior leaflet portion, each leaflet portion having a proximal edge, a distal edge, and side edges extending between the proximal edge and the distal edge. The template further includes a plurality of substantially straight elongated chordae portions each having a proximal end connected to the distal edge of one of the at least two leaflet portions and a distal end extending therefrom and one or more papillary muscle head portions formed at a commissure between distal ends of at least two of the plurality of chordae portions. A total width of the leaflet portions of the template is substantially equal to a circumference of a native annulus of a heart valve.
    Type: Application
    Filed: February 23, 2018
    Publication date: February 20, 2020
    Inventors: Vinay Badhwar, Antonio D'Amore, Yasumoto Matsumura, William R. Wagner
  • Biodegradable, Antioxidant, Thermally Responsive Injectable Hydrogel and Uses Therefor
    Publication number: 20190216847
    Abstract: Provided herein are antioxidant, thermally-responsive copolymer-based compositions and methods of making and using the compositions, e.g., for treatment of ischemia reperfusion injury in a patient. The copolymer comprises a hydrocarbyl backbone, and a plurality of pendant pyrrolidone, antioxidant radical, polyester oligomer, and N-alkyl amide groups.
    Type: Application
    Filed: October 6, 2017
    Publication date: July 18, 2019
    Inventors: William R. Wagner, Yasumoto Matsumura, Murugesan Velayutham, Yang Zhu