Abstract: A liquid transfer monitoring method to monitor a transfer state of a liquid such as a sample or a reagent having a high transparency which transmits light is provided. The liquid transfer monitoring method comprises a step of transferring a liquid 30 held in a first liquid holding portion 21 to a second liquid holding portion 22 connected to the first liquid holding portion 21, a step of acquiring information 40 relating to a scattered light intensity obtained by irradiating light 91 on the irregular inner surface 23 of at least one of the first liquid holding portion 21 and the second liquid holding portion 22 after starting the transfer of the liquid 30, and a step of monitoring the liquid transfer to the second liquid holding portion 22 based on the information 40 relating to the intensity of scattered light.

Abstract: Disclosed is a liquid-sealed cartridge in which a liquid is transferred by a centrifugal force generated when the liquid-sealed cartridge is rotated around a rotation shaft, including: a liquid storage portion configured to store the liquid therein; a seal having an outer peripheral portion connected to the liquid storage portion, the seal being configured to seal the liquid storage portion; a flow path connected to the liquid storage portion via the seal, through which the liquid in the liquid storage portion is transferred by the centrifugal force in a direction away from the rotation shaft, wherein, when the seal receives a pressing force, the seal is inclined in a pressing direction, with one portion of the outer peripheral portion thereof remaining connected with the liquid storage portion, and the other portion of the outer peripheral portion being separated from the liquid storage portion.

Abstract: Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.

Abstract: Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.

Abstract: A liquid transfer monitoring method to monitor a transfer state of a liquid such as a sample or a reagent having a high transparency which transmits light is provided. The liquid transfer monitoring method comprises a step of transferring a liquid 30 held in a first liquid holding portion 21 to a second liquid holding portion 22 connected to the first liquid holding portion 21, a step of acquiring information 40 relating to a scattered light intensity obtained by irradiating light 91 on the irregular inner surface 23 of at least one of the first liquid holding portion 21 and the second liquid holding portion 22 after starting the transfer of the liquid 30, and a step of monitoring the liquid transfer to the second liquid holding portion 22 based on the information 40 relating to the intensity of scattered light.

Abstract: A high frequency power supply device and power supplying method are disclosed, which can rapidly and accurately control power used for generation of plasmas. The device includes a first high frequency power supply, providing power at frequency f1, and a second high frequency power supply providing power at frequency f2 (f1>f2). The first power supply includes: a first high frequency oscillator, which excites the high frequency power at the first frequency and has a variable frequency; a first power amplification block, which amplifies the power of the high frequency oscillator; a heterodyne detection block, which performs heterodyne detection of a reflected wave; and a first control block, which receives a signal after detection of the heterodyne detection block and a traveling wave signal, and controls an oscillating frequency of the first high frequency oscillating block and an output of the first power amplification block.

Abstract: Disclosed is a liquid-sealed cartridge in which a liquid is transferred by a centrifugal force generated when the liquid-sealed cartridge is rotated around a rotation shaft, including: a liquid storage portion configured to store the liquid therein; a seal having an outer peripheral portion connected to the liquid storage portion, the seal being configured to seal the liquid storage portion; a flow path connected to the liquid storage portion via the seal, through which the liquid in the liquid storage portion is transferred by the centrifugal force in a direction away from the rotation shaft, wherein, when the seal receives a pressing force, the seal is inclined in a pressing direction, with one portion of the outer peripheral portion thereof remaining connected with the liquid storage portion, and the other portion of the outer peripheral portion being separated from the liquid storage portion.

Abstract: Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.

Abstract: A high frequency power supply device and power supplying method are disclosed, which can rapidly and accurately control power used for generation of plasmas. The device includes a first high frequency power supply, providing power at frequency f1, and a second high frequency power supply providing power at frequency f2 (f1>f2). The first power supply includes: a first high frequency oscillator, which excites the high frequency power at the first frequency and has a variable frequency; a first power amplification block, which amplifies the power of the high frequency oscillator; a heterodyne detection block, which performs heterodyne detection of a reflected wave; and a first control block, which receives a signal after detection of the heterodyne detection block and a traveling wave signal, and controls an oscillating frequency of the first high frequency oscillating block and an output of the first power amplification block.

Abstract: A tissue cutting device is described, a representative one of which includes: a handle part; a head unit including comprising a plurality of blades arranged so as to extend substantially parallel with a longitudinal direction of the handle part at intervals and a blade holding portion for holding the plurality of blades; and a head holding part located at the distal end of the handle part, for holding the head.

Abstract: An extraction device for extracting an analyte from living tissue is disclosed that comprises a power source; a first electrode and second electrode connected to the power source; and a holding unit for holding a collecting medium for collecting analyte extracted from living tissue, wherein the collecting medium is in contact with both the first electrode and second electrode continuously. An analyzer comprising the extraction device, method for extracting an analyte, and method for extracting and analyzing an analyte are also described.

Abstract: The present invention is to present a measuring device which can conduct stable extraction and measurement of interstitial fluid. The measuring device comprises: a device body which comprises an extraction part for extracting body fluid from a living body and a measuring part for measuring a biological component contained in the extracted body fluid; a holding member which holds the device body and has an opening part for defining a measurement area on the living body; and a mounting member for mounting the holding member on the living body; wherein the measurement area on the living body is defined by the opening part when the holding member is mounted on the living body by the mounting member.

Abstract: An extracting kits for extracting analyte through the skin of a living body are disclosed that comprises an inserting device comprising needles for forming a plurality of extraction holes in the skin through the stratum corneum but not reaching the subcutaneous tissue and an extracting device for extracting the analyte into a liquid supplied into the extraction holes by supplying the liquid into the plurality of extraction holes. An extracting device and extracting method are also described.

Abstract: This method of analyzing a biological component includes steps of arranging an extraction medium holding part configured to be capable of holding a prescribed quantity of extraction medium for holding an extract extracted from a subject on the skin of the subject, transferring the extraction medium stored in a liquid storing part storing substantially the same quantity of the extraction medium as the prescribed quantity to the extraction medium holding part, transferring at least part of the extraction medium holding the extracted extract to a reaction part, and analyzing a result of detecting the extract.

Abstract: Extraction device for extracting an analyte from living tissue through skin are described that include: (a) a first electrode part having a contact area with the skin of less than about 50 mm2; (b) a through-current electrode part; and (c) a power supply part for supplying electrical energy to the first electrode part and the through-current electrode part, and for extracting an analyte in the first electrode part. Analyzers, extraction methods, and analysis methods are also described.

Abstract: A micropore forming system comprising: a microneedle chip having microneedles for forming micropores in a skin of a living body; a chip container for detachably housing the microneedle chip; and a micropore forming device for detachably holding the microneedle chip and for contacting the microneedles of the microneedle chip to the skin.

Abstract: An indoor unit has first, second indoor side terminals to which first, second interconnection lines respectively, are connected at their one end, a third indoor side terminal to which a third interconnection line is connected at its one end, a relay with one end connected to the second indoor side terminal and another end connected to the third indoor side terminal, and a CPU. The outdoor unit has first, second outdoor side terminals as outdoor side power-receiving terminals to which the first, second interconnection lines, respectively, are connected at their other end, a third outdoor side terminal to which the third interconnection line is connected at its other end, and an outdoor control section to which electric power is supplied via the first, third outdoor side terminals. The CPU of the indoor unit turns off the switch part in the standby state.

Abstract: The present invention provides a method of measuring skin conductance which can obtain an accuracy measurement result, comprising the steps of: supplying a low conductivity medium as a medium for holding tissue fluid that contains a predetermined component of a subject to a medium containing part; disposing the medium containing part on an extraction region of a skin of the subject; extracting tissue fluid through the extraction region into the low conductivity medium within the medium containing part; supplying electric power between a first electrode for supplying electric power to the extraction region and a second electrode for supplying electric power to the skin outside the extraction region; and measuring the conductance of the extraction region based on the electric power supplied between the first electrode and second electrode. A method of analyzing a component concentration, a skin conductance measuring apparatus, and a component concentration analyzer are also disclosed.

Abstract: A high frequency power supply device and power supplying method are disclosed, which can rapidly and accurately control power used for generation of plasmas. The device includes a first high frequency power supply, providing power at frequency f1, and a second high frequency power supply providing power at frequency f2 (f1>f2). The first power supply includes: a first high frequency oscillator, which excites the high frequency power at the first frequency and has a variable frequency; a first power amplification block, which amplifies the power of the high frequency oscillator; a heterodyne detection block, which performs heterodyne detection of a reflected wave; and a first control block, which receives a signal after detection of the heterodyne detection block and a traveling wave signal, and controls an oscillating frequency of the first high frequency oscillating block and an output of the first power amplification block.

Abstract: An analyzer (a blood glucose meter), which shows minor measurement errors even in the case of conducting the extraction and detection of an analyte in parallel, can be obtained. This blood glucose meter (100) comprises a sensor unit (26) having a measurement face (26a) to which glucose extracted from a subject is supplied, a light-receiving element (34) outputting a signal based on the glucose supplied to the measurement face, a sensor contact face (23a) to be in contact with the measurement face and a skin contact face (23b) to be in contact with the skin of the subject, as well as a mesh sheet (23) for supplying the glucose from the skin contact face to the measurement face. The mesh sheet is designed so that the distance between the measurement face and the skin is maintained substantially at a constant level during the contact with the skin.