Abstract: To provide a micropore forming apparatus capable of increasing the amount of interstitial fluid extracted from micropores formed in the skin of a subject. The micropore forming apparatus includes a skin contact part that has a plurality of microneedles for piercing the skin of the subject, and a force exerting part for exerting a force on the skin contact part toward the skin of the subject. The force exerting part is configured so as to exert a force on the microneedles toward the skin at a position at which the microneedles of the skin contact part are to pierce the skin of the subject.

Abstract: A body fluid collection device for collecting body fluid through the skin, comprising: a sheet-like substrate provided with an adhesive surface; a first collection body for collecting body fluid, provided on the adhesive surface; a first detachable sheet which is detachably adhered on the adhesive surface so as to cover the first collection body; and a second detachable sheet which is detachably adhered on the adhesive surface, wherein one end of the second detachable sheet in a predetermined direction is overlaid on the far end of the first detachable sheet in the predetermined direction, and part of the far end of the first detachable sheet is separated from the adhesive surface in a non-adhered state is disclosed.

Abstract: To provide a method configured to effectively control in a simplifier manner any adverse influences from perspiration excreted from a skin currently measured when a biogenic substance from tissue fluid extracted through fine pores is measured, the method includes steps of: forming a film having a water impermeability on the test subject's skin; forming fine pores in the skin coated with the film so as to penetrate through the film; extracting the tissue fluid from the test subject through the skin where the fine pores are formed; storing the constituent to be measured and inorganic ions of the extracted tissue fluid; obtaining an ion information relating to a quantity of the stored inorganic ions and a constituent information relating to a quantity of the stored constituent; and obtaining an analysis value relating to the quantity of the constituent based on the ion information and the constituent information.

Abstract: To provide a micropore forming apparatus capable of increasing the amount of interstitial fluid extracted from micropores formed in the skin of a subject. The micropore forming apparatus includes a skin contact part that has a plurality of microneedles for piercing the skin of the subject, and a force exerting part for exerting a force on the skin contact part toward the skin of the subject. The force exerting part is configured so as to exert a force on the microneedles toward the skin at a position at which the microneedles of the skin contact part are to pierce the skin of the subject.

Abstract: This sensor with a fine needle having a channel formed therein includes a fine needle portion of resin provided with a channel for sucking body fluid, a liquid sump portion, connected with the channel, pooling the body fluid, a sensor portion for detecting a specific component contained in the body fluid pooled in the liquid sump portion, a cover portion, in which the sensor portion is arranged, arranged to cover the liquid sump portion and an air hole connected with the channel formed in the fine needle portion through the liquid sump portion.

Abstract: An in vivo component measurement method comprises steps of: extracting a tissue fluid from a biological body into an extraction medium and accumulating an objective component and an inorganic ion in the extracted tissue fluid; acquiring ion information on a quantity of the accumulated inorganic ion; acquiring a component information on a quantity of the accumulated objective component; and acquiring an analysis value on the quantity of the objective component based on the ion information and the component information.