Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: A reinforcement rib is provided at the reverse side of the elongated side molding in longitudinal direction and a portion of the reinforcement rib is elevated to form a welding rib. In the clip as an attachment member, a rib hole is provided for inserting the welding rib therein and the open side of the rib hole from which the welding rib is projecting is formed with a larger bore. The side molding body is integrally formed with the attachment member by housing a dislocation preventing portion formed by heat riveting a tip end of the welding rib inserted into the rib hole of the attachment member. Thus integrated side molding with the attachment member is attached to the outer panel of the vehicle by the leg portion provided at the attachment member.

Abstract: A rotary printing press has one or two inking rollers each in rolling engagement with both an ink supply cylinder and a plate cylinder. Each inking roller is identically supported by a first pair of roller support members mounted one adjacent each end of the ink supply cylinder for pivotal motion about the axis of that cylinder, and a second pair of roller support members mounted to the first pair for pivotal motion about an axis parallel to the axis of the ink supply cylinder, the second pair of roller support members rotatably supporting one inking roller therebetween. Adjusting screws act between the two pairs of roller support members for adjustably varying the nip width between the ink supply cylinder and each inking roller.

Abstract: A holding part of a cowl inner panel is disposed below a hood seal part of a cowl louver main body away therefrom by a predetermined distance, and the hood seal part is deformed by the impact force of a predetermined size or larger from the hood panel so as to reduce the deformation load on the hood panel. In the case impact force of a predetermined size or larger is applied on the hood panel, the impact force is transmitted to the hood seal part so that the hood seal part is deformed. Accordingly, the hood panel can be deformed drastically so that the impact to be applied from the hood panel onto the opposite party of the collision can be alleviated. Further, both end parts of a seal main body made from an elastic soft material, having a substantially U-shaped cross-section is fixed with a cowl louver and a flat plate part, respectively as well as the cowl louver and the flat plate part are fixed on the car body directly or indirectly.

Abstract: A method of manufacturing an orifice member used in a nozzle for ink-jet printing includes a first step of applying an adhesive onto one surface of a synthetic resin member; a second step of forming at least one through-opening in a metallic member such that the through-opening extends in a direction perpendicular to the direction of penetration of the through-opening; a third step of bonding together the metallic member having the through-opening and the synthetic resin member via the adhesive; and after the bonding step, a fourth step of forming a plurality of through-holes having substantially the same diameter in a portion of the synthetic resin member corresponding to the through-opening of the metallic member such that the through-holes are aligned at a substantially constant pitch along the through-opening of the metallic member and such that the through-holes do not deviate from an area corresponding to the through-opening.

Abstract: A reinforcement rib is provided at the reverse side of the elongated side molding in longitudinal direction and a portion of the reinforcement rib is elevated to form a welding rib.

Abstract: A rotary printing press has one or two inking rollers each in rolling engagement with both an ink supply cylinder and a plate cylinder. Each inking roller is identically supported by means comprising a first pair of roller support members mounted one adjacent each end of the ink supply cylinder for pivotal motion about the axis of that cylinder, and a second pair of roller support members mounted to the first pair for pivotal motion about an axis parallel to the axis of the ink supply cylinder, the second pair of roller support members rotatably supporting one inking roller therebetween. Adjusting screws act between the two pairs of roller support members for adjustably varying the nip width between the ink supply cylinder and each inking roller.

Abstract: A nozzle for ink-jet printing includes a manifold, a vibration element, and an orifice member. The manifold has an outside surface extending in the longitudinal direction of the manifold as well as a hollow space. The hollow space has an opening opened in the outside surface such that the opening extends along the longitudinal direction while maintaining a substantially constant width. The vibrating element is attached to at least one outside surface other than the outside surface in which the hollow space is opened. The orifice member is brought into contact and attached to the outside surface in which the hollow space is opened. The orifice member is composed of a metallic member provided in contact with the manifold, and a synthetic resin member bonded to the metallic member through use of adhesive. The metallic member has at least one through-opening at a position facing the opening of the hollow space of the manifold such that the through-opening communicates with the opening of the hollow space.

Abstract: There is disclosed a simple and compact additional printing apparatus for a rotary press and a printing unit. The additional printing apparatus includes an ink jet printing device comprising an ink jetting nozzle section and unnecessary ink droplet deflection unit. The ink jetting nozzle section includes a plurality of orifices arranged in a row and ink droplet formation unit. The unnecessary ink droplet deflection unit corresponds to each of the orifices. The ink jet printing device is disposed at a predetermined position in proximity to a paper web pass at which position an additional image can be printed on paper web in alignment with an image printed by the printing cylinder.

Abstract: There is provided a construction which comprises: a printing plate receiving means that is arranged at a position remote from the periphery of a plate cylinder for supporting a printing plate lock-up hook portion in parallel to the axis of the plate cylinder and as capable of displacement in parallel to that axis; a receiving position determining means for positioning at a predetermined position of the printing plate receiving means the printing plate lock-up hook portion mounted thereon; and a stop position determining means for stopping the printing plate receiving means at a predetermined position relative to a side end surface of the plate cylinder. The invention enables a printing plate being locked up to be positioned with an extremely high precision, yet in a short period of time, corresponding to the position where it is to be locked up, relative to an axially displaced plate cylinder.

Abstract: There is provided a construction which comprises: a printing plate receiving means that is arranged at a position remote from the periphery of a plate cylinder for supporting a printing plate lock-up hook portion in parallel to the axis of the plate cylinder and as capable of displacement in parallel to that axis; a receiving position determining means for positioning at a predetermined position of the printing plate receiving means the printing plate lock-up hook portion mounted thereon; and a stop position determining means for stopping the printing plate receiving means at a predetermined position relative to a side end surface of the plate cylinder. The invention enables a printing plate being locked up to be positioned with an extremely high precision, yet in a short period of time, corresponding to the position where it is to be locked up, relative to an axially displaced plate cylinder.

Abstract: An improved width adjusting device for a paper web which can assure the printing apparatus is free from trouble caused by stored paper dust and gathered ink, includes at least one pressure force applying device with respect to at least one side surface of the paper web travelling through at least one of the printing sections, and at least one drive control device for making the pressure force applying device move in a different direction and/or at a different speed from that of the travelling paper web.

Abstract: A printing plate delivery system for a multi-stage printing press, in which a plurality of printing stages are arranged in vertical direction, comprises a vertical transporting device having a carrier movable in vertical direction between a loading position where a printing plate set along the height direction of the printing press being loaded and a printing plate transfer positions at the corresponding height positions to the printing stages for transferring the printing plate, and receiving device provided corresponding to each of the printing stages and cooperated with the vertical transporting device for receiving the printing plate from the carrier at the corresponding transfer position.

Abstract: The present invention provides an angle-bar device for use in a rotary press, which aims at removing ink and paper debris, etc deposited on the whole peripheral surfaces of the angle-bars by rotating the angle-bars continuously so as to increase the tension on the paper web which is running around and between the angle-bars. This angle-bar device comprises: at least two pieces of angle-bars (1a; 1b) disposed rotatively on the upstream and downstream sides, respectively, of the direction of running of a paper web; driving means (2a ; 2b) each for rotatively driving each of the angle-bars; a start controlling means (3) connected operatively with the driving means and adapted to control the starting of the driving means. The device further comprises an operation controlling means (4) for detecting the operating condition of the rotary printing press, which is connected with the start controlling means (3) so that it can send out output signal to the start controlling means.

Abstract: A cooling and heating concurrent operation type of multiple refrigeration cycle comprises an indoor unit including a variable delivery type of compressor and an outdoor heat exchanger; indoor units including indoor heat exchangers, respectively; triple connection pipes of a high pressure gas pipe, a high pressure liquid pipe and a low pressure gas pipe, the triple connection pipes connecting between the outdoor unit and the indoor units; pressure detection means for detecting the intake pressure of the compressor and the discharge pressure of the compressor; and calculation and control means for comparing two detected values of the intake pressure and the discharge pressure of the compressor with two set values of a set intake pressure and a set discharge pressure, and for making variable controls of the compression capability of the compressor and the heat exchange capability of the outdoor heat exchanger based on the respective deviation values between the respective detected values and the respective set v

Abstract: The guide roller apparatus in a rotary press using a paper roll includes: rotatable guide rollers; and a power transmission mechanism for connecting two or more guide rollers with each other in such a manner that at least one of the guide rollers is rotated at a circumferential speed different from those of the other guide rollers.