Patents by Inventor Yasushi Abiko

Yasushi Abiko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5965615
    Abstract: The invention relates to a hydroxyl radical scavenger and a remedy composition for a disease caused by a hydroxyl radical, which each comprise, as an active ingredient, a betaine represented by the formula (1):(CH.sub.3).sub.3 N.sup.+ (CH.sub.2).sub.n COO.sup.- (1)wherein n is an integer of 1-5, or an acid-addition salt or ester salt thereof. The betaine is useful in treating a disease caused by a hydroxyl radical, in particular, cardiopathy.
    Type: Grant
    Filed: March 25, 1997
    Date of Patent: October 12, 1999
    Assignees: Taiho Pharmaceutical Co., Ltd., Valsts zinatniska iestade - bezpelnas organizacija Latvijas organiskas sintezes instituts
    Inventors: Ivars Kalvinsh, Maris Veveris, Yasushi Abiko, Kiyotaka Tajima
  • Patent number: 5602123
    Abstract: A therapeutic agent for myocardial ischemic damages or reperfusion injuries which contains, as an active ingredient, a compound of the following formula (1), an acid addition salt thereof, or a hydrate thereof: ##STR1## wherein R.sup.1 to R.sup.6 are lower alkoxy groups and A and A' are lower alkylene groups; a method for treating those disorders which uses the above compound; and use of the compound in the manufacture of such a therapeutic agent. The therapeutic agent has an excellent action of recovering lowered heart functions caused by myocardial ischemia-reflow, and have low toxicity.
    Type: Grant
    Filed: October 26, 1995
    Date of Patent: February 11, 1997
    Assignee: Kowa Co., Ltd.
    Inventors: Yasushi Abiko, Hiroko Hashizume, Akiyoshi Hara, Yoichi Yamauchi, Junichi Kawagoe
  • Patent number: 4874772
    Abstract: An agent for treatment and prevention of asthma comprising 2-[2-phenyl-2-(2-pyridyl)]ethyl-2-imidazoline or a salt thereof as an active ingredient is disclosed.
    Type: Grant
    Filed: April 27, 1988
    Date of Patent: October 17, 1989
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Setsuo Kobayashi, Tsugio Nakazawa, Yasumasa Yoshie, Yasushi Abiko, Kinya Kameda
  • Patent number: 4288441
    Abstract: A compound of the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represents a member selected from the group consisting of hydrogen and nicotinoyl, with the proviso that R.sub.1, R.sub.2 and R.sub.3 do not all simultaneously represent hydrogen, and the nontoxic acid addition salts thereof.
    Type: Grant
    Filed: July 30, 1980
    Date of Patent: September 8, 1981
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Tosaku Miki, Akashi Eriguchi, Yasushi Abiko, Kinya Kameda
  • Patent number: 4138491
    Abstract: A method for treating diabetes comprising administering a therapeutically effective amount of a 2-(2,2-disubstituted)ethylimidazoline of the general formula (I) ##STR1## wherein R is a phenyl group or a 2-pyridyl group or the pharmaceutically acceptable acid addition salts thereof, to a patient having diabetes.
    Type: Grant
    Filed: June 24, 1977
    Date of Patent: February 6, 1979
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Fumiyoshi Ishikawa, Akira Kosasayama, Yoshifumi Watanabe, Yasushi Abiko, Kin-ya Kameda, Shin-etu Ono
  • Patent number: 4136188
    Abstract: 2-SUBSTITUTED-1,3-DIAZACYCLIC COMPOUNDS OF THE FORMULA: ##STR1## wherein R.sub.1 represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; R.sub.2 represents a hydrogen atom, a lower alkoxycarbonyl group, an aliphatic acyl group or an aromatic acyl group, the aromatic ring of which may have one or more substituents selected from a halogen atom, a lower alkyl group, a lower alkoxy group, an acyl group and an acyloxy group; R.sub.3 represents a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group or an aralkyl group; R.sub.4 represents a hydrogen atom, a lower alkyl group or an aryl group; R.sub.6 represents a cyclohexyl group, a pyridyl group or a phenyl group which may have a substituent selected from a halogen atom, a lower alkyl group and a lower alkoxy group; A represents -N.dbd.
    Type: Grant
    Filed: June 25, 1976
    Date of Patent: January 23, 1979
    Assignee: Daiichi Seiyaku Co., Ltd.
    Inventors: Fumiyoshi Ishikawa, Akira Kosasayama, Yoshifumi Watanabe, Yasushi Abiko, Kin-Ya Kameda, Shin-etu Ono