Abstract: An antibody against spike protein of SARS-CoV-2 is provided, the antibody having a specific heavy chain variable region and a specific light chain variable region, or a fragment of the antibody, the antibody or fragment thereof inhibiting the binding between the spike protein of SARS-CoV-2 and ACE2, the antibody or fragment thereof inhibiting SARS-CoV-2 infection; and a pharmaceutical composition including the antibody or fragment thereof and a pharmaceutically acceptable carrier, the pharmaceutical composition including two or more kinds of the antibody or fragment thereof.

Abstract: The present invention provides a recombinant vaccinia virus serving as a clinically usable preventive vaccine for COVID-19 (vaccine for SARS-CoV-2), etc. The recombinant vaccinia virus of the present invention is characterized by comprising the whole or part of cDNA encoding nonstructural proteins or structural protein derived from SARS-CoV-2, and an expression promoter.

Abstract: The present invention addresses the problem of providing a more convenient method for in vitro proliferating a virus belonging to the family Coronaviridae at high proliferation accuracy. This problem is solved by an in vitro virus proliferation method, said method comprising a step for culturing kidney-derived cells, which have been contacted with the virus belonging to the family Coronaviridae, with a use of a cell culture medium to which a protease having an optimum pH of from 7 to 9 is added.

Abstract: Provided are: a recombinant vaccinia virus which is effective for the prevention of the development of a disease by the infection by H7 avian influenza virus and has high safety; and a vaccine against H7 avian influenza virus, which comprises the recombinant vaccinia virus. The recombinant vaccinia virus according to the present invention is a recombinant vaccinia virus having such a structure that an expression promoter and the full length or a part of cDNA encoding hemagglutinin protein of H7 avian influenza virus are contained in the genome for vaccinia virus strain DIs.

Abstract: An AlN sintered compact includes AlN crystal grains and a grain boundary phase, and the grain boundary phase is lower in Vickers hardness than the AlN crystal grains.

Abstract: This invention discloses an immunosuppressive cell-capturing material comprising a molded body that includes: a readily hydrolyzable condensation polymer having an amino group; a poorly hydrolyzable polymer coating the readily hydrolyzable condensation polymer; and a ligand-conjugated poorly hydrolyzable polymer coating the poorly hydrolyzable polymer, wherein the ligand is at least one selected from the group consisting of a NH2 group, a secondary amino group, a tertiary amino group, a polyamine residue, a basic cyclic polypeptide residue, an aminoglycosidic compound residue, chloroquine, primaquine, mefloquine, imiquimod, and nystatin, and wherein the content of the amino group in the molded body is 150 ?mol/g or less. The invention also discloses an immunosuppressive cell-capturing column filled with the capturing material.

Abstract: This invention discloses an immunosuppressive cell-capturing material comprising a molded body that includes: a readily hydrolyzable condensation polymer having an amino group; a poorly hydrolyzable polymer coating the readily hydrolyzable condensation polymer; and a ligand-conjugated poorly hydrolyzable polymer coating the poorly hydrolyzable polymer, wherein the ligand is at least one selected from the group consisting of a NH2 group, a secondary amino group, a tertiary amino group, a polyamine residue, a basic cyclic polypeptide residue, an aminoglycosidic compound residue, chloroquine, primaquine, mefloquine, imiquimod, and nystatin, and wherein the content of the amino group in the molded body is 150 ?mol/g or less. The invention also discloses an immunosuppressive cell-capturing column filled with the capturing material.

Abstract: A server is installed with host bus adapters (HBAs). The HBA causes light-emitting components thereon to emit light in abnormal light emission patterns upon falling into an abnormal condition, and in predetermined light emission patterns upon receiving a predetermined command. A method for managing the HBA includes storing abnormal light emission patterns of the HBA, detecting an abnormality as to whether a predetermined HBA is in an abnormal condition, obtaining current light emission patterns of a light-emitting component of an abnormal HBA which is detected to be in the abnormal condition in the detecting, and controlling light emission by sending the predetermined command to all of the HBAs except the abnormal one to cause the light-emitting components thereof to emit light in the predetermined light emission patterns, when the current light emission patterns, obtained in the obtaining, do not match the abnormal light emission patterns stored in the storing.

Abstract: A server is installed with host bus adapters (HBAs). The HBA causes light-emitting components thereon to emit light in abnormal light emission patterns upon falling into an abnormal condition, and in predetermined light emission patterns upon receiving a predetermined command. A method for managing the HBA includes storing abnormal light emission patterns of the HBA, detecting an abnormality as to whether a predetermined HBA is in an abnormal condition, obtaining current light emission patterns of a light-emitting component of an abnormal HBA which is detected to be in the abnormal condition in the detecting, and controlling light emission by sending the predetermined command to all of the HBAs except the abnormal one to cause the light-emitting components thereof to emit light in the predetermined light emission patterns, when the current light emission patterns, obtained in the obtaining, do not match the abnormal light emission patterns stored in the storing.

Abstract: Provided is an aluminum nitride sintered body having a larger area and a smaller thickness as compared to the conventional art, wherein the aluminum nitride sintered body has flatness with controlled warpage and/or waviness height. Methods of producing such sintered body, and further a metallized substrate and a heater using such sintered body are also provided. An aluminum nitride substrate 1 has a maximum length of 320 mm or more, a thickness of more than 0 mm and 2 mm or less, a warpage of 0 ?m/mm or more and less than 2 ?m/mm, and a local waviness height of 0 ?m or more and 100 ?m or less.

Abstract: Provided is an aluminum nitride sintered body having a larger area and a smaller thickness as compared to the conventional art, wherein the aluminum nitride sintered body has flatness with controlled warpage and/or waviness height. Methods of producing such sintered body, and further a metallized substrate and a heater using such sintered body are also provided. An aluminum nitride substrate 1 has a maximum length of 320 mm or more, a thickness of more than 0 mm and 2 mm or less, a warpage of 0 ?m/mm or more and less than 2 ?m/mm, and a local waviness height of 0 ?m or more and 100 ?m or less.

Abstract: A circuit arrangement design method includes a step of performing a logic conversion of logic, the logic forming a circuit arrangement where a cell arrangement and a connection arrangement between cells are provisionally arranged prior to a detailed mounting design, and thereby wiring efficiency is improved.

Abstract: In a microwave module including a transmitting portion circuit and a receiving portion circuit, the transmitting portion circuit and the receiving portion circuit are respectively constructed by transmission lines of different kinds in which polarization planes are orthogonal to each other, and are constructed on the same surface of the same substrate. For example, one of the transmitting portion circuit and the receiving portion circuit is constructed by a microstrip line, and the other is constructed by a coplanar line. Further, one of the transmitting portion circuit and the receiving portion circuit is constructed by a microstrip line, and the other is constructed by a slot line. By this, there is obtained a microwave module in which mutual interference by an electromagnetic field between element circuits in the module can be suppressed, the circuits can be arranged close to each other without requiring a shielding member, and miniaturization of the module can be realized.

Abstract: By connecting a grounding conductor pattern directly to a grounding terminal of a field-effect transistor and connecting a series circuit comprising a stabilized resistor and an open-circuit stub having a length equal to quarter of a parallel resonance frequency, undesirable parallel resonance caused by the grounding conductor pattern and the open-circuit stub is suppressed, and a voltage drop in the stabilized resistor is suppressed when a bias voltage is applied to the field-effect transistor. Accordingly, the operation of a microwave amplifier is stabilized.

Abstract: A dual-frequency matching circuit of the present invention comprises an output terminal to which a load is connected, an input terminal through which an input signal is input to the load, a series resonance circuit, which is composed of a series capacitor and a series inductor connected in series to the series capacitor and disposed in such a manner that it is connected in series to the load when observed from the input terminal side, and a parallel resonance circuit, which is composed of a parallel capacitor and a parallel inductor connected in parallel to the parallel capacitor, and disposed in such a manner that it is connected in parallel to the entire portion of the load and the series resonance circuit when observed from the input terminal side.

Abstract: A microwave amplifier (10) of the present invention contains such an arrangement that both an inductor (12) and a resistor (13) are loaded in a parallel manner between a source electrode of a field-effect transistor (11) and the ground. Since the inductor (12) has a stray capacitance component (B), the inductor (12) is resonated at a resonant frequency “f0”. However, since the source electrode of the field-effect transistor (11) is grounded via a resistor (13) connected in parallel to the inductor (12), even when the inductor (12) is opened due to a resonant operation, the field-effect transistor (11) is operated under normal condition. As a result, the operation of the microwave amplifier (10) is stabilized.

Abstract: By connecting a grounding conductor pattern directly to a grounding terminal of a field-effect transistor and connecting a series circuit comprising a stabilized resistor and an open-circuit stub having a length equal to quarter of a parallel resonance frequency, undesirable parallel resonance caused by the grounding conductor pattern and the open-circuit stub is suppressed, and a voltage drop in the stabilized resistor is suppressed when a bias voltage is applied to the field-effect transistor. Accordingly, the operation of a microwave amplifier is stabilized.