Patents by Inventor Yasushi Kazuno

Yasushi Kazuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NITRILE HYDRATASE VARIANT
    Publication number: 20150093803
    Abstract: A nitrile hydratase variant of the present invention comprises substitution of at least one amino acid with another amino acid to improve two or more properties of nitrile hydratase by substitution of one amino acid.
    Type: Application
    Filed: September 19, 2014
    Publication date: April 2, 2015
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Daisuke Mochizuki, Junko Tokuda
  • Nitrile hydratase variant
    Patent number: 8871484
    Abstract: A nitrile hydratase variant of the present invention comprises substitution of at least one amino acid with another amino acid to improve two or more properties of nitrile hydratase by substitution of one amino acid.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: October 28, 2014
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Daisuke Mochizuki, Junko Tokuda
  • NITRILE HYDRATASE VARIANT
    Publication number: 20110212506
    Abstract: A nitrile hydratase variant of the present invention comprises substitution of at least one amino acid with another amino acid to improve two or more properties of nitrile hydratase by substitution of one amino acid.
    Type: Application
    Filed: November 12, 2009
    Publication date: September 1, 2011
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Daisuke Mochizuki, Junko Tokuda
  • Process for producing chiral hydroxyaldehyde compounds
    Patent number: 7402710
    Abstract: An industrial process for producing hydroxyaldehydes efficiently, by solving the problems of conventional DERA, such as low stability against aldehydes, low catalytic activity for aldol condensation, and the difficulty of controlling the number of acetaldehyde molecules to be condensed, is provided. According to the process, aldol condensation of a substituted or unsubstituted aliphatic aldehyde compound having 2 to 6 carbon atoms with acetaldehyde is conducted by using D-2-deoxyribose-5-phosphate aldolase which is highly stable against aldehydes and has high catalytic activity for aldol condensation, whereby a hydroxyaldehyde compound having the number of carbon atoms increased by two or four can be produced.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: July 22, 2008
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Norikazu Higashimura, Toshihisa Ohshima, Haruhiko Sakuraba
  • Process For Producing Chiral Hydroxyaldehyde Compounds
    Publication number: 20070196906
    Abstract: An industrial process for producing hydroxyaldehydes efficiently, by solving the problems of conventional DERA, such as low stability against aldehydes, low catalytic activity for aldol condensation, and the difficulty of controlling the number of acetaldehyde molecules to be condensed, is provided. According to the process, aldol condensation of a substituted or unsubstituted aliphatic aldehyde compound having 2 to 6 carbon atoms with acetaldehyde is conducted by using D-2-deoxyribose-5-phosphate aldolase which is highly stable against aldehydes and has high catalytic activity for aldol condensation, whereby a hydroxyaldehyde compound having the number of carbon atoms increased by two or four can be produced.
    Type: Application
    Filed: March 28, 2005
    Publication date: August 23, 2007
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Norikazu Higashimura, Toshihisa Ohshima, Haruhiko Sakuraba