Patents by Inventor Yasushi Nakano

Yasushi Nakano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210003486
    Abstract: A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.
    Type: Application
    Filed: September 24, 2020
    Publication date: January 7, 2021
    Inventors: Takuji AIMIYA, Hideki GOUDA, Hisatake OKADA, Yasushi NAKANO, Kohsuke GONDA, Motohiro TAKEDA, Noriaki OHUCHI
  • Publication number: 20200355694
    Abstract: The present invention relates to a method for evaluating a drug involved in angiogenesis. The method includes a drug administration step (A) of administering a drug involved in angiogenesis to a subject having a lesion. The method further includes: an imaging step (1) of performing radiography on a subject in a state where metal nanoparticles are present in a blood vessel or an imaging step (2) of performing fluorescence staining and fluorescence imaging using a dimeric protein; and evaluating the drug using an image acquired in the imaging step (1) or (2).
    Type: Application
    Filed: November 20, 2018
    Publication date: November 12, 2020
    Inventors: Takuji AIMIYA, Naoko FURUSAWA, Yasushi NAKANO, Kohsuke GONDA, Yoh HAMADA, Masayuki TOKUNAGA
  • Patent number: 10809167
    Abstract: A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: October 20, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Takuji Aimiya, Hideki Gouda, Hisatake Okada, Yasushi Nakano, Kohsuke Gonda, Motohiro Takeda, Noriaki Ohuchi
  • Publication number: 20200325291
    Abstract: A second resin-impregnated fiber sheet (12) contains fibers extending in a first direction. A third resin-impregnated fiber sheet (13) contains fibers extending in a second direction that is different from the first direction. A first main surface (1a) is provided with a plurality of first linear protruding portions (1a1) extending in the first direction. A second main surface (1b) is provided with a plurality of second linear protruding portions (1b1) extending in the second direction.
    Type: Application
    Filed: June 22, 2017
    Publication date: October 15, 2020
    Applicant: SEKISUI CHEMICAL CO., LTD.
    Inventors: Yoshinori NAKANO, Masanori NAKAMURA, Setsuo NAKAJIMA, Masakazu KADOYAMA, Yasushi NAKATA
  • Patent number: 10747348
    Abstract: According to one embodiment, a sensor-equipped display device includes a first substrate includes a first electrode located in a display area in which an image is displayed, a second substrate includes a second electrode which is located in the display area, and outputs a sensor signal, and a flexible substrate includes a first connection portion connected to the first substrate and a second connection portion connected to the second substrate, the flexible substrate includes a common base layer extending between the first connection portion and the second connection portion.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: August 18, 2020
    Assignee: Japan Display Inc.
    Inventors: Koji Noguchi, Yasushi Nakano, Masaki Murase
  • Publication number: 20200233519
    Abstract: A display device is provided and includes a first substrate comprising first and second areas, first and second terminals located in the first area, and first wiring electrically connects the first terminal with the second terminal; a second substrate comprising a detection electrode for sensing and a third terminal electrically connected to the detection electrode; and connecting member comprising a base layer, and a conductive member electrically connects first and third terminals, wherein the first area is an area in which the second substrate does not overlap the first substrate, the second area is an area in which the first substrate and the second substrate overlap each other, the connecting member does not extend outside first substrate, the conductive member is provided on an undersurface of the base layer, and the undersurface is opposed to the first surface and the third surface.
    Type: Application
    Filed: April 8, 2020
    Publication date: July 23, 2020
    Inventors: Koji NOGUCHI, Masaki MURASE, Yasushi NAKANO, Koji ISHIZAKI
  • Publication number: 20200227931
    Abstract: Provided are a battery pack and an electrical apparatus by which information can be transmitted at an appropriate timing from the battery pack to a device body. A battery pack (10) includes: a serial communication reception circuit (31) and a temperature information transmission circuit (32); an LS terminal that is selectively connected to the serial communication reception circuit (31) or the temperature information transmission circuit (32); a first switching circuit (21) that is provided between the LS terminal and the serial communication reception circuit (31) and the temperature information transmission circuit (32); and a V terminal that is connected to the first switching circuit (21). The first switching circuit (21) switches between connecting the serial communication reception circuit (31) or the temperature information transmission circuit (32) to the LS terminal according to a signal inputted from the V terminal.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 16, 2020
    Applicant: Koki Holdings Co., Ltd.
    Inventors: Satoshi YAMAGUCHI, Yasushi NAKANO, Hiroyuki HANAWA, Kazuhiko FUNABASHI
  • Publication number: 20200212505
    Abstract: A battery pack includes cell units in which upper and lower battery cells are connected in series, wherein an output of series-connection and an output of parallel-connection can be switched. The cell units are respectively provided with protection circuit ICs for monitoring the state of the battery cells, and only the protection circuit on the lower cell unit side is provided with a controller 350 including a microcomputer. To adjust the power consumption for the microcomputer only provided in the lower cell unit, the circuit on the upper cell unit side is provided with a current consumption control means including dummy loads. The current consumption control means is operated in conjunction with the start-up of the microcomputer in the controller so as to equalize power consumption on the upper cell unit side and the lower cell unit side.
    Type: Application
    Filed: May 30, 2018
    Publication date: July 2, 2020
    Applicant: Koki Holdings Co., Ltd.
    Inventors: Yasushi Nakano, Satoshi YAMAGUCHI, Hiroyuki HANAWA, Kazuhiko FUNABASHI, Tomomasa NISHIKAWA, Shota KANNO, Toshio Mizoguchi, Takuya Teranishi
  • Publication number: 20200161609
    Abstract: The electrical apparatus, in which a series connection state and a parallel connection state of an upper cell unit including five battery cells and a lower cell unit can be automatically switched by means of a difference in a terminal shape on the electrical apparatus body side, has a terminal holder and holds apparatus side terminals. The terminal holder, which establishes an electrically connected state with the connection terminals of the battery pack, is provided with two parallel protruding parts that extend in the forward-backward direction, and second rail grooves fitted to the protruding parts on the electrical apparatus side. Due to the fitting, relative movement of the terminal holder and the battery pack in the vertical direction can be suppressed, and wear on the apparatus side terminals can be greatly suppressed.
    Type: Application
    Filed: June 29, 2018
    Publication date: May 21, 2020
    Applicant: Koki Holdings Co., Ltd.
    Inventors: Takuhiro Murakami, Tomomasa NISHIKAWA, Shinji Watanabe, Junpei SATO, Hikaru Tamura, Shota KANNO, Toshio Mizoguchi, Yasushi Nakano, Hiroyuki HANAWA, Kazuhiko FUNABASHI, Masayuki Ogura, Takuya Teranishi, Junichi Toukairin, Shota Takeuchi, Yusuke FUNABIKI
  • Patent number: 10656740
    Abstract: According to one embodiment, a sensor-equipped display device includes a first substrate includes a first area and a second area adjacent to the first area, the first substrate includes a first terminal and a second terminal which are located in the first area, and a first wiring which electrically connects the first terminal and the second terminal, a second substrate includes a detection electrode, and a third terminal electrically connected to the detection electrode, and a connecting member which electrically connects the first terminal and the third terminal, at least a part of the first wiring being extended from the first terminal toward the second area.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: May 19, 2020
    Assignee: Japan Display Inc.
    Inventors: Koji Noguchi, Masaki Murase, Yasushi Nakano, Koji Ishizaki
  • Publication number: 20200124122
    Abstract: A brake lining is provided that is to be pressed against a sliding surface of a brake disk fastened to a wheel or an axle of a railway vehicle. The brake lining includes: a plurality of friction members arranged to be spaced from each other, each of the friction members having a front surface that is to face the sliding surface; a back board fastened to a back surface of each of the friction members; and a base plate supporting each friction member at a region including a center portion of the respective friction members. Two friction members are taken as a pair, and the back board that is fastened to the pair of friction members is a one-piece member, and a width of the back board at a space between the friction members of the pair of friction members is greater than a width of the friction member.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 23, 2020
    Inventors: Takahiro FUJIMOTO, Yuiko SAKAYAMA, Atsushi SAKAGUCHI, Kazutaka ASABE, Takeshi NAKANO, Makoto IKEDA, Isao SHIMAZOE, Yasushi KARINO, Hajime TAKAMI
  • Publication number: 20200127339
    Abstract: A battery pack which has cell units in which top-side and bottom-side battery cells are connected in series, and is capable of switching the connection state of the cell units, wherein a control unit monitors voltage imbalances between the cell units, and also monitors whether or not a cell unit contact failure has occurred. In order to stop a charging/discharging when a contact failure occurs, a signal (abnormality stoppage signal or charging stoppage signal) for stopping discharge is produced and outputted to the electrical device body-side.
    Type: Application
    Filed: July 24, 2018
    Publication date: April 23, 2020
    Applicant: Koki Holdings Co., Ltd.
    Inventors: Yasushi Nakano, Satoshi YAMAGUCHI, Hiroyuki HANAWA, Kazuhiko FUNABASHI, Tomomasa NISHIKAWA, Shota KANNO, Toshio Mizoguchi
  • Patent number: 10626810
    Abstract: A control apparatus for a diesel engine includes a neighboring temperature estimating section which estimates a temperature of a neighborhood of a glow plug that heats an interior of a cylinder upon startup, and a supercharging pressure control section which controls a supercharging pressure in such a way that a rotation fluctuation of the engine does not increase, on the basis of the estimated temperature of the neighborhood of the glow plug.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: April 21, 2020
    Assignee: NISSAN MOTOR CO., LTD.
    Inventors: Toru Nishizawa, Shuichi Iio, Kiyoshi Ohga, Ryota Nakayama, Takashi Yamazaki, Yoshihiro Imaoka, Yasushi Ohmura, Isshou Uehara, Masahiko Nakano, Manabu Hasegawa
  • Patent number: 10627325
    Abstract: A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: April 21, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Takuji Aimiya, Hideki Gouda, Hisatake Okada, Yasushi Nakano
  • Publication number: 20200116718
    Abstract: It is an object of the present invention to provide a tissue staining method that makes it possible to observe both information on the morphology of a tissue and information on a biological substance such as an antigen molecule to be detected on a single section and in a single view field. The present invention provides a tissue staining method, including carrying out (A) a HE (hematoxylin-eosin) staining, and (B) a histochemical staining, serially on a single tissue section, wherein the histochemical staining is defined as a histochemical technique for detecting a biological substance to be detected in a tissue in a visible manner by use of a binding reaction between the biological substance to be detected and a probe biological substance capable of binding specifically to the biological substance to be detected.
    Type: Application
    Filed: December 16, 2019
    Publication date: April 16, 2020
    Inventors: Hideki GOUDA, Hisatake OKADA, Yasushi NAKANO, Kohsuke GONDA, Noriaki OHUCHI, Mika WATANABE
  • Publication number: 20200056278
    Abstract: A sprayed coating having a multilayer structure including a lower layer made a sprayed coating containing a rare earth oxide, and a surface layer made of another sprayed coating containing a rare earth fluoride and/or a rare earth oxyfluoride, the multilayered sprayed coating having a volume resistivity at 23° C. and a volume resistivity at 200° C., the volume resistivity at 23° C. being 1×109 to 1×1012 ?·cm, and a temperature index of the volume resistivities defined by the ratio of the volume resistivity at 200° C. to the volume resistivity at 23° C. being 0.1 to 10.
    Type: Application
    Filed: August 13, 2019
    Publication date: February 20, 2020
    Applicant: Shin-Etsu Chemical Co., Ltd.
    Inventors: Ryo Iwasaki, Noriaki Hamaya, Yasushi Takai, Hajime Nakano
  • Patent number: 10551378
    Abstract: It is an object of the present invention to provide a tissue staining method that makes it possible to observe both information on the morphology of a tissue and information on a biological substance such as an antigen molecule to be detected on a single section and in a single view field. The present invention provides a tissue staining method, including carrying out (A) a HE (hematoxylin-eosin) staining, and (B) a histochemical staining, serially on a single tissue section, wherein the histochemical staining is defined as a histochemical technique for detecting a biological substance to be detected in a tissue in a visible manner by use of a binding reaction between the biological substance to be detected and a probe biological substance capable of binding specifically to the biological substance to be detected.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: February 4, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Hideki Gouda, Hisatake Okada, Yasushi Nakano, Kohsuke Gonda, Noriaki Ohuchi, Mika Watanabe
  • Patent number: 10551386
    Abstract: The present invention provides a biological substance detection method for specifically detecting a biological substance from a pathological specimen, by which method, when immunostaining using a fluorescent label and staining for morphological observation using a staining agent for morphological observation are simultaneously performed, the results of fluorescence observation and immunostaining can be assessed properly even if the fluorescent label and/or the staining agent is/are deteriorated by irradiation with an excitation light. The biological substance detection method according to the present invention is characterized in that the brightness retention rate of an immunostained part is in a range of 80% to 120% in relation to the brightness retention rate of a part stained for morphological observation when the fluorescent label used for the immunostaining is observed.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: February 4, 2020
    Assignee: KONICA MINOLTA, INC.
    Inventors: Kensaku Takanashi, Hisatake Okada, Yasushi Nakano, Kohsuke Gonda, Noriaki Ohuchi, Mika Watanabe
  • Patent number: 10534379
    Abstract: A pressure reducing valve includes a body, an annular valve seat, a valve element, and a pressing mechanism configured to press the valve element. The pressing mechanism includes a plug provided downstream of the valve seat and having a plug hole, and a pin including a sliding portion and an upstream end, the sliding portion having a shaft shape and being inserted in the plug hole such that a gap is provided between the sliding portion and an inner peripheral surface of the plug hole, and the upstream end being provided upstream of the sliding portion so as to contact the valve element. A fitting length of the sliding portion with respect to the plug hole and the gap between the sliding portion and the plug hole satisfy 0.0005 L<C<0.00908 L, where L indicates the fitting length, and C indicates the gap.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: January 14, 2020
    Assignees: JTEKT CORPORATION, TOYOTA TECHNICAL DEVELOPMENT CORPORATION, SOKEN, INC.
    Inventors: Kazuhisa Sugiyama, Koji Nishi, Akira Nakano, Yutaka Hotta, Akira Yamashita, Shota Yamamoto, Yasushi Mitsuishi
  • Patent number: 10532878
    Abstract: A pill case (100) includes a pocket (9) which receives one pill (10) from an accommodation unit (8) in which a plurality of pills (10) are accommodated, and an extraction port (11) for ejecting the pill (10) in the pocket (9) to the outside. The pill case (100) includes a manipulation unit (for example, pill ejection button (4) and pill tray (5)) which converts a state in which the pill (10) in the pocket (9) cannot be ejected through the extraction port (11) to a state in which the pill (10) in the pocket (9) can be ejected through the extraction port (11) by being manipulated by a user. The pill case (100) includes a moving unit which is moved by indirectly or directly receiving a pressure from the pill (10) in the pocket (9) according to the moving manipulation to the manipulation unit, and a detection unit which detects that the moving unit is moved up to a position of the moving unit which corresponds to a state in which the pill (10) in the pocket (9) can be ejected.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: January 14, 2020
    Assignees: NEC CORPORATION, NEC PLATFORMS, LTD
    Inventors: Yasuyuki Homma, Yasushi Nakano