Patents by Inventor Yasutake Toyoshima

Yasutake Toyoshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sample substrate for laser desorption ionization-mass spectrometry, and method and device both using the same for laser desorption ionization-mass spectrometry
    Patent number: 8558169
    Abstract: An object of the present invention is to provide a sample substrate for laser desorption ionization mass spectrometry for LDI-MS which substrate enables mass spectrometric analysis of a sample correctly at high sensitivity without generating interference peaks upon irradiation of the sample to laser light and uniform application of the sample onto a base. Another object of the invention is to provide a mass spectrometer (device) employing the sample substrate. In the sample substrate for laser desorption ionization mass spectrometry, the sample substrate is formed of a base and carbon nanowalls having wall surfaces onto which a sample to undergo mass spectrometry is applied, wherein the carbon nanowalls are formed on the base so as to stand on the base. The surfaces of carbon nanowalls serve as an ionization medium and hydrophilized. By use of the sample substrate, mass spectrometry of a sample having a wide range (high to low) molecular weight can be reliably performed at high precision and sensitivity.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: October 15, 2013
    Inventors: Masaru Hori, Hiroaki Sato, Yasutake Toyoshima, Mineo Hiramatsu
  • SAMPLE SUBSTRATE FOR LASER DESORPTION IONIZATION-MASS SPECTROMETRY, AND METHOD AND DEVICE BOTH USING THE SAME FOR LASER DESORPTION IONIZATION-MASS SPECTROMETRY
    Publication number: 20120175515
    Abstract: An object of the present invention is to provide a sample substrate for laser desorption ionization mass spectrometry for LDI-MS which substrate enables mass spectrometric analysis of a sample correctly at high sensitivity without generating interference peaks upon irradiation of the sample to laser light and uniform application of the sample onto a base. Another object of the invention is to provide a mass spectrometer (device) employing the sample substrate. In the sample substrate for laser desorption ionization mass spectrometry, the sample substrate is formed of a base and carbon nanowalls having wall surfaces onto which a sample to undergo mass spectrometry is applied, wherein the carbon nanowalls are formed on the base so as to stand on the base. The surfaces of carbon nanowalls serve as an ionization medium and hydrophilized. By use of the sample substrate, mass spectrometry of a sample having a wide range (high to low) molecular weight can be reliably performed at high precision and sensitivity.
    Type: Application
    Filed: July 29, 2010
    Publication date: July 12, 2012
    Applicant: National University Corporation Nagoya University
    Inventors: Masaru Hori, Hiroaki Sato, Yasutake Toyoshima, Mineo Hiramatsu