Abstract: The present invention provides a technique for preparing a porous cellulose medium, through the gelation of a solution in which cellulose acetate as a raw material is dissolved, which does not cause a reaction involving the migration of substances. Specifically, a method for producing a porous cellulose medium is provided which includes the steps of gelling a flowable homogeneous composition containing cellulose acetate, an organic solvent, and water through a decrease in temperature; and hydrolyzing the cellulose acetate contained in the resulting gel.

Abstract: The present invention relates to composite materials useful for purifying proteins obtained from biological feedstocks. The composite materials of the invention comprise a porous support having an average pore size of 5 to 500 nm, said porous support being filled with a first polymer which is cross-linked, and a second polymer which is not crosslinked and is covalently bonded to the external surface of the cross-linked polymer-filled porous support.

Abstract: The present invention relates to composite materials useful for purifying proteins obtained from biological feedstocks. The composite materials of the invention comprise a porous support having an average pore size of 5 to 500 nm, said porous support being filled with a polymer which is cross-linked, wherein the polymer is selected from polyvinylamines or polyallylamines having a weight average molecular weight (Mw) of 2,000 to 500,000 Da and a hydrolysis degree of the formamide groups of at least 66%, with the proviso that a polyvinylamine having a weight average molecular weight (Mw) of 27,200 Da and a hydrolysis degree of 70% and a polyvinylamine having a weight average molecular weight (Mw) of 50,000 Da and a hydrolysis degree of 95% are excluded.

Abstract: Provided are a technique for preparing a porous cellulose medium without using a special gelling agent for a solution in which cellulose acetate serving as a raw material is dissolved; and a porous cellulose medium and the like produced using the technique. A method for producing a porous cellulose medium comprises the step of preparing a flowable homogeneous composition comprising cellulose acetate, a basic compound, and a solvent including water, and gelling the composition by deacetylation reaction of the cellulose acetate.

Abstract: Provided are a technique for preparing a porous cellulose medium without using a special gelling agent for a solution in which cellulose acetate serving as a raw material is dissolved; and a porous cellulose medium and the like produced using the technique. A method for producing a porous cellulose medium comprises the step of preparing a flowable homogeneous composition comprising cellulose acetate, a basic compound, and a solvent including water, and gelling the composition by deacetylation reaction of the cellulose acetate.

Abstract: The present invention provides a technique for preparing a porous cellulose medium, through the gelation of a solution in which cellulose acetate as a raw material is dissolved, which does not cause a reaction involving the migration of substances. Specifically, a method for producing a porous cellulose medium is provided which includes the steps of gelling a flowable homogeneous composition containing cellulose acetate, an organic solvent, and water through a decrease in temperature; and hydrolyzing the cellulose acetate contained in the resulting gel.

Abstract: Provided is a separating agent comprising a carrier and a ligand fixed on a surface of a carrier by chemical bonding, in which the carrier is a core-shell particle formed of a non-porous core and a porous shell, the shell having a pore diameter of 9 nm or more and formed of a hydrolysate of polyalkoxysiloxane, and the ligand is an optically active polymer, optically inactive polyester, protein, nucleic acid, or optically active organic compound with a molecular weight of 50 to 1000.

Abstract: Provided is a separating agent comprising a carrier and a ligand fixed on a surface of a carrier by chemical bonding, in which the carrier is a core-shell particle formed of a non-porous core and a porous shell, the shell having a pore diameter of 9 nm or more and formed of a hydrolysate of polyalkoxysiloxane, and the ligand is an optically active polymer, optically inactive polyester, protein, nucleic acid, or optically active organic compound with a molecular weight of 50 to 1000.