Patents by Inventor Yasuto Nakai

Yasuto Nakai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160280744
    Abstract: The purpose of the present invention is to provide a novel protein, which have such excellent pH responsiveness that the antibody binding property to the Fc region of the immunoglobulin in the neutral region is improved and the binding property to the Fc region of the immunoglobulin in the weakly acidic region is much decreased when compared to the wild-type proteins such as protein G and protein A that have affinity for the protein comprising the Fc region of the immunoglobulin G (IgG), and a mutant-type protein (an improved protein) comprising their domain mutant. The present invention relates to a protein constituted by linking plural domains having affinity for a protein comprising the Fc region of the immunoglobulin G (IgG) with linkers, wherein an extended length to the maximum of the linker is 80-240 angstrom.
    Type: Application
    Filed: October 1, 2014
    Publication date: September 29, 2016
    Inventors: Shinya HONDA, Hideki WATANABE, Chuya YOSHIDA, Yutaka ISOBE, Momoko UEDA, Yasuto NAKAI
  • Publication number: 20150183820
    Abstract: The purpose of the present invention is to provide a superior protein with more decreased binding property to the Fc region of immunoglobulin and/or more decreased binding property to the Fab region thereof in the weakly acidic region in comparison with a protein containing an extracellular domain of a wild-type protein G without spoiling the high antibody binding property in the neutral region, and to allow the antibody to be easily captured and recovered without denaturing it by means of a capturing agent and column comprising the above protein.
    Type: Application
    Filed: July 29, 2013
    Publication date: July 2, 2015
    Inventors: Shinya Honda, Hideki Watanabe, Chuya Yoshida, Momoko Ueda, Yasuto Nakai, Yutaka Isobe
  • Patent number: 7520603
    Abstract: In an inkjet printer including first to n-th paper storages, such as a magazine type storage or a cassette type storage, and associated first to n-th upstream transport lines (where n is a natural number larger than 1), a paper carrier (switchback unit) is provided which has a roller pair reciprocable between any of first to n-th receive points corresponding to the downstream ends of the first to n-th upstream transport lines, respectively, and a forwarding point corresponding to the upstream end of a downstream transport line by means of a moving mechanism. The paper carrier is configured so that the roller pair receives and grips, at one of the first to n-th receive points, a sheet of printing paper transported from the associated upstream transport line, the moving mechanism moves the roller pair from the receive point to the forwarding point and the gripped sheet of printing paper is forwarded at the forwarding point to the downstream transport line.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: April 21, 2009
    Assignee: Noritsu Koki Co., Ltd.
    Inventors: Masaaki Tsuji, Hiroomi Kondou, Noboru Michiue, Keiichi Yamamoto, Yasuto Nakai, Mitsuru Yasuda
  • Publication number: 20060087546
    Abstract: In an inkjet printer including first to n-th paper storages, such as a magazine type storage or a cassette type storage, and associated first to n-th upstream transport lines (where n is a natural number larger than 1), a paper carrier (switchback unit) is provided which has a roller pair reciprocable between any of first to n-th receive points corresponding to the downstream ends of the first to n-th upstream transport lines, respectively, and a forwarding point corresponding to the upstream end of a downstream transport line by means of a moving mechanism. The paper carrier is configured so that the roller pair receives and grips, at one of the first to n-th receive points, a sheet of printing paper transported from the associated upstream transport line, the moving mechanism moves the roller pair from the receive point to the forwarding point and the gripped sheet of printing paper is forwarded at the forwarding point to the downstream transport line.
    Type: Application
    Filed: October 21, 2005
    Publication date: April 27, 2006
    Applicant: Noritsu Koki Co., Ltd.
    Inventors: Masaaki Tsuji, Hiroomi Kondou, Noboru Michiue, Keiichi Yamamoto, Yasuto Nakai, Mitsuru Yasuda