Patents by Inventor Yasuyoshi Naishiro

Yasuyoshi Naishiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and reagent for diagnosis and/or evaluation of progression of graft-versus-host disease
    Patent number: 9631014
    Abstract: Disclosed is a method of diagnosing graft-versus-host disease, comprising measuring the level of CCL8 protein in a sample obtained from a subject as an indicator for the diagnosis or course of graft-versus-host disease. Also a diagnostic reagent for graft-versus-host disease comprising an anti-CCL8 antibody is disclosed. The method of the present invention enables diagnosis of the onset of graft-versus-host disease and monitoring of the progress, in particular, differential diagnosis between graft-versus-host disease and an infectious disease. The present invention also provides a method for treating graft-versus-host disease utilizing the anti-CCL8 antibody.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: April 25, 2017
    Assignee: SAPPORO MEDICAL UNIVERSITY
    Inventors: Tsukasa Hori, Yasuo Kokai, Yasuyoshi Naishiro, Hiroyuki Tsutsumi, Kohzoh Imai
  • METHOD AND REAGENT FOR DIAGNOSIS AND/OR EVAULATION OF PROGRESSION OF GRAFT-VERSUS-HOST DISEASE
    Publication number: 20140234335
    Abstract: Disclosed is a method of diagnosing graft-versus-host disease, comprising measuring the level of CCL8 protein in a sample obtained from a subject as an indicator for the diagnosis or course of graft-versus-host disease. Also a diagnostic reagent for graft-versus-host disease comprising an anti-CCL8 antibody is disclosed. The method of the present invention enables diagnosis of the onset of graft-versus-host disease and monitoring of the progress, in particular, differential diagnosis between graft-versus-host disease and an infectious disease. The present invention also provides a method for treating graft-versus-host disease utilizing the anti-CCL8 antibody.
    Type: Application
    Filed: April 3, 2014
    Publication date: August 21, 2014
    Applicant: SAPPORO MEDICAL UNIVERSITY
    Inventors: Tsukasa HORI, Yasuo KOKAI, Yasuyoshi NAISHIRO, Hiroyuki TSUTSUMI, Kohzoh IMAI
  • METHOD AND REAGENT FOR DIAGNOSIS AND/OR EVALUATION OF PROGRESSION OF GRAFT-VERSUS-HOST DISEASE
    Publication number: 20130267430
    Abstract: Disclosed is a method of diagnosing graft-versus-host disease, comprising measuring the level of CCL8 protein in a sample obtained from a subject as an indicator for the diagnosis or course of graft-versus-host disease. Also a diagnostic reagent for graft-versus-host disease comprising an anti-CCL8 antibody is disclosed. The method of the present invention enables diagnosis of the onset of graft-versus-host disease and monitoring of the progress, in particular, differential diagnosis between graft-versus-host disease and an infectious disease. The present invention also provides a method for treating graft-versus-host disease utilizing the anti-CCL8 antibody.
    Type: Application
    Filed: June 14, 2012
    Publication date: October 10, 2013
    Applicant: SAPPORO MEDICAL UNIVERSITY
    Inventors: Tsukasa HORI, Yasuo KOKAI, Yasuyoshi NAISHIRO, Hiroyuki TSUTSUMI, Kohzoh IMAI
  • METHOD AND REAGENT FOR DIAGNOSIS AND/OR EVALUATION OF PROGRESSION OF GRAFT-VERSUS-HOST DISEASE
    Publication number: 20130065779
    Abstract: Disclosed is a method of diagnosing graft-versus-host disease, comprising measuring the level of CCL8 protein in a sample obtained from a subject as an indicator for the diagnosis or course of graft-versus-host disease. Also a diagnostic reagent for graft-versus-host disease comprising an anti-CCL8 antibody is disclosed. The method of the present invention enables diagnosis of the onset of graft-versus-host disease and monitoring of the progress, in particular, differential diagnosis between graft-versus-host disease and an infectious disease. The present invention also provides a method for treating graft-versus-host disease utilizing the anti-CCL8 antibody.
    Type: Application
    Filed: June 14, 2012
    Publication date: March 14, 2013
    Inventors: Tsukasa HORI, Yasuo Kokai, Yasuyoshi Naishiro, Hiroyuki Tsutsumi, Kohzoh Imai
  • METHOD FOR DETECTION OR TREATMENT OF GRAFT VERSUS HOST DISEASE
    Publication number: 20100183586
    Abstract: Disclosed is a method of diagnosing graft-versus-host disease, comprising measuring the level of CCL8 protein in a sample obtained from a subject as an indicator for the diagnosis or course of graft-versus-host disease. Also a diagnostic reagent for graft-versus-host disease comprising an anti-CCL8 antibody is disclosed. The method of the present invention enables diagnosis of the onset of graft-versus-host disease and monitoring of the progress, in particular, differential diagnosis between graft-versus-host disease and an infectious disease. The present invention also provides a method for treating graft-versus-host disease utilizing the anti-CCL8 antibody.
    Type: Application
    Filed: June 23, 2008
    Publication date: July 22, 2010
    Inventors: Tsukasa Hori, Yasuo Kokai, Yasuyoshi Naishiro, Hiroyuki Tsutsumi, Kohzoh Imai