Patents by Inventor Yasuyoshi Takeshita

Yasuyoshi Takeshita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the treatment of xerostomia
    Patent number: 5580880
    Abstract: A method for the treatment of xerostomia not caused by Sjogren's syndrome comprising administering to an affected individual an effective amount of a derivative of spirooxathiolane-quinuclidine.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 3, 1996
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Harumi Handa, Yasuyoshi Takeshita
  • Composition and method for treating Sjoegren syndrome disease
    Patent number: 5340821
    Abstract: A composition for treating a Sjoegren syndrome disease is disclosed. The composition comprising derivative of spirooxathiolane-quinuclidine of the following formula (I), ##STR1## wherein Z is .dbd.CR.sup.1 R.sup.2, wherein R.sup.1 and R.sup.2 may be the same or different and each represents hydrogen, alkyl, cyclopentyl, cyclohexyl, aryl, diarylmethylol, or alkyl which may be substituted by one or more aryl groups, or an acid addition salt thereof, or an acid addition salt thereof, as an effective component. Especially effective is an administration of a hydrochloric acid addition salt of 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine.
    Type: Grant
    Filed: July 7, 1993
    Date of Patent: August 23, 1994
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Nobuaki Abe, Yasuyoshi Takeshita
  • Isoquinoline derivatives and salts thereof
    Patent number: 5116985
    Abstract: The invention provides novel compounds and salts thereof, have the structure ##STR1## wherein R.sub.1 is a guianidinobenzoyloxy group and R.sub.2 is a hydrogen atom, a hydroxy, cyano, --COR.sub.3 (wherein R.sub.3 is an amino or lower alkyl group) or --COOR.sub.4 group [wherein R.sub.4 is a hydrogen atom, lower alkyl, phenyl, benzyl or --CH.sub.2 CONR.sub.5 R.sub.6 group (wherein R.sub.5 and R.sub.6 are the same or different and selected from a hydrogen atom and lower alkyl groups)], and wherein R.sub.1 is a hydroxy group and wherein R.sub.2 is a --COR.sub.3 (wherein R.sub.3 is an amino or lower alkyl group) or --COOR.sub.4 group [wherein R.sub.4 is a (C.sub.1, C.sub.3 or C.sub.4) alkyl, phenyl, benzyl or --CH.sub.2 CONR.sub.5 R.sub.6 group (wherein R.sub.5 and R.sub.6 are the same or different and selected from a hydrogen atom and lower alkyl groups)]. The compounds, wherein R.sub.1 is a guanidinobenzoyloxy group, are useful protease inhibitors as anti-trypsin agents.
    Type: Grant
    Filed: December 19, 1990
    Date of Patent: May 26, 1992
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Yasuyoshi Takeshita, Hiroshi Nakamura, Susumu Ishiguro, Noboru Kwaguchi, Shin'ichi Shimada, Tadayoshi Koyama, Motohide Seya, Noriko Abe, Shin Nomoto
  • Alprenolol derivatives
    Patent number: 4927959
    Abstract: Novel alprenolol derivatives represented by the formula: ##STR1## wherein R is ##STR2## and hydrochlorides thereof are disclosed.
    Type: Grant
    Filed: September 2, 1988
    Date of Patent: May 22, 1990
    Assignee: Snow Brand Milk Products Co., Ltd.
    Inventors: Shinichi Shimada, Noboru Kawaguchi, Tadayoshi Koyama, Akinori Wakaiki, Keiji Hayashi, Yasuyoshi Takeshita, Masamichi Nakakoshi, Gosei Kawanishi