Patents by Inventor Yasuyuki Kawashima

Yasuyuki Kawashima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9778178
    Abstract: A blood cell analyzer comprises a flow cell configured to flow a measurement specimen containing blood cells, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, a first light receiving portion configured to receive first scattered light obtained by irradiating the blood cells passing through the flow cell with light from the first light source, a second light receiving portion configured to receive second scattered light obtained by irradiating the blood cells passing through the flow cell with light from the second light source, and a control section configured to discriminate at least red blood cells from the blood cells contained in the measurement specimen based on detection signals output from the first light receiving portion and the second light receiving portion, respectively.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: October 3, 2017
    Assignee: SYSMEX CORPORATION
    Inventors: Kazuhiro Yamada, Yasuyuki Kawashima, Seiichiro Tabata
  • Patent number: 9422588
    Abstract: An apparatus for measuring bacteria includes a sampling device for processing fluorescently stained bacteria, a detector for detecting size information from the bacteria in the sample, and a detector for detecting fluorescence information expressing intensity of fluorescent light emitted by the bacteria. The apparatus further includes a processor and memory that includes programs for creating a scattergram representing a distribution of the bacteria based on the size information and the fluorescence information detected, analyzing the distribution of the bacteria in the scattergram, and determining whether the bacteria in the sample is bacillus or coccus based on a result of the analysis.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: August 23, 2016
    Assignee: SYSMEX CORPORATION
    Inventor: Yasuyuki Kawashima
  • Patent number: 9329133
    Abstract: An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: May 3, 2016
    Assignee: SYSMEX CORPORATION
    Inventors: Yousuke Tanaka, Junya Inoue, Masatsugu Ozasa, Yasuyuki Kawashima
  • Publication number: 20140295487
    Abstract: A blood cell analyzer comprises a flow cell configured to flow a measurement specimen containing blood cells, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, a first light receiving portion configured to receive first scattered light obtained by irradiating the blood cells passing through the flow cell with light from the first light source, a second light receiving portion configured to receive second scattered light obtained by irradiating the blood cells passing through the flow cell with light from the second light source, and a control section configured to discriminate at least red blood cells from the blood cells contained in the measurement specimen based on detection signals output from the first light receiving portion and the second light receiving portion, respectively.
    Type: Application
    Filed: March 27, 2014
    Publication date: October 2, 2014
    Applicant: Sysmex Corporation
    Inventors: Kazuhiro YAMADA, Yasuyuki KAWASHIMA, Seiichiro TABATA
  • Publication number: 20140295488
    Abstract: A blood cell analyzer comprising a flow cell configured to flow a measurement specimen containing blood cells, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, a first light receiving portion configured to receive first scattered light generated by irradiating the blood cells in the measurement specimen with light from the first light source, a second light receiving portion configured to receive second scattered light generated by irradiating the blood cells in the measurement specimen with light from the second light source, and a control section configured to classify at least white blood cells from the blood cells contained in the measurement specimen, based on a detection signal output from the first light receiving portion and a detection signal output from the second light receiving portion.
    Type: Application
    Filed: March 27, 2014
    Publication date: October 2, 2014
    Applicant: SYSMEX CORPORATION
    Inventors: Yusuke KONISHI, Yasuyuki KAWASHIMA, Kazuhiro YAMADA, Keiko YOSHIKAWA
  • Publication number: 20140127794
    Abstract: An apparatus for measuring bacteria includes a sampling device for processing fluorescently stained bacteria, a detector for detecting size information from the bacteria in the sample, and a detector for detecting fluorescence information expressing intensity of fluorescent light emitted by the bacteria. The apparatus further includes a processor and memory that includes programs for creating a scattergram representing a distribution of the bacteria based on the size information and the fluorescence information detected, analyzing the distribution of the bacteria in the scattergram, and determining whether the bacteria in the sample is bacillus or coccus based on a result of the analysis.
    Type: Application
    Filed: January 9, 2014
    Publication date: May 8, 2014
    Applicant: Sysmex Corporation
    Inventor: Yasuyuki KAWASHIMA
  • Patent number: 8669097
    Abstract: An apparatus for measuring bacteria that includes a sampling device for processing fluorescently stained bacteria, a detector for detecting size information from the bacteria in the sample, and a detector for detecting fluorescence information expressing intensity of fluorescent light emitted by the bacteria. The apparatus further includes a processor and memory that includes programs for creating a scattergram representing a distribution of the bacteria based on the size information and the fluorescence information detected, analyzing the distribution of the bacteria in the scattergram, and determining whether the bacteria in the sample is bacillus or coccus based on a result of the analysis.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: March 11, 2014
    Assignee: Sysmex Corporation
    Inventor: Yasuyuki Kawashima
  • Patent number: 8647859
    Abstract: An apparatus for analyzing bacteria is described that includes an analytic sample preparation section for preparing an analytic sample by treating a specimen so as to generate a morphological difference between Gram-negative bacteria and Gram-positive bacteria, a detector for detecting optical information from each particle contained in the analytic sample and an analyzing section for detecting Gram-positive bacteria contained on the basis of the detected optical information. A method for analyzing bacteria is also described.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: February 11, 2014
    Assignee: Sysmex Corporation
    Inventor: Yasuyuki Kawashima
  • Publication number: 20130316444
    Abstract: An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.
    Type: Application
    Filed: August 5, 2013
    Publication date: November 28, 2013
    Applicant: SYSMEX CORPORATION
    Inventors: Yousuke TANAKA, Junya Inoue, Masatsugu Ozasa, Yasuyuki Kawashima
  • Patent number: 8501482
    Abstract: An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: August 6, 2013
    Assignee: Sysmex Corporation
    Inventors: Yousuke Tanaka, Junya Inoue, Masatsugu Ozasa, Yasuyuki Kawashima
  • Patent number: 8309360
    Abstract: A reagent for analyzing urine is described. The reagent comprises a fungus membrane damaging agent for damaging a cellular membrane of yeast-like fungus in urine; a first dye for staining yeast-like fungus so that a fluorescent intensity of damaged yeast-like fungus becomes more intense than that of erythrocyte in urine; and a second dye for staining sperm in urine so that a fluorescent intensity of sperm becomes more intense than that of the damaged yeast-like fungus.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: November 13, 2012
    Assignee: Sysmex Corporation
    Inventor: Yasuyuki Kawashima
  • Publication number: 20120178122
    Abstract: An apparatus for analyzing bacteria is described that includes an analytic sample preparation section for preparing an analytic sample by treating a specimen so as to generate a morphological difference between Gram-negative bacteria and Gram-positive bacteria, a detector for detecting optical information from each particle contained in the analytic sample and an analyzing section for detecting Gram-positive bacteria contained on the basis of the detected optical information. A method for analyzing bacteria is also described.
    Type: Application
    Filed: March 7, 2012
    Publication date: July 12, 2012
    Inventor: Yasuyuki KAWASHIMA
  • Publication number: 20120166093
    Abstract: An apparatus for analyzing bacteria is described that includes an analytic sample preparation section for preparing an analytic sample by treating a specimen so as to generate a morphological difference between Gram-negative bacteria and Gram-positive bacteria, a detector for detecting optical information from each particle contained in the analytic sample and an analyzing section for detecting Gram-positive bacteria contained on the basis of the detected optical information. A method for analyzing bacteria is also described.
    Type: Application
    Filed: March 7, 2012
    Publication date: June 28, 2012
    Inventor: Yasuyuki Kawashima
  • Patent number: 8153418
    Abstract: An apparatus for analyzing bacteria is described that includes an analytic sample preparation section for preparing an analytic sample by treating a specimen so as to generate a morphological difference between Gram-negative bacteria and Gram-positive bacteria, a detector for detecting optical information from each particle contained in the analytic sample and an analyzing section for detecting Gram-positive bacteria contained on the basis of the detected optical information. A method for analyzing bacteria is also described.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: April 10, 2012
    Assignee: Sysmex Corporation
    Inventor: Yasuyuki Kawashima
  • Publication number: 20100261225
    Abstract: An apparatus for analyzing bacteria is described that includes an analytic sample preparation section for preparing an analytic sample by treating a specimen so as to generate a morphological difference between Gram-negative bacteria and Gram-positive bacteria, a detector for detecting optical information from each particle contained in the analytic sample and an analyzing section for detecting Gram-positive bacteria contained on the basis of the detected optical information. A method for analyzing bacteria is also described.
    Type: Application
    Filed: June 24, 2010
    Publication date: October 14, 2010
    Inventor: Yasuyuki Kawashima
  • Patent number: 7662631
    Abstract: Sample analyzers for analyzing a sample are described that include a pipette for suctioning the sample; a sample preparation unit for preparing a measured sample by diluting the sample supplied by the pipette with an acidic solution; a pipette washing unit for washing the pipette with the acidic solution; a detection unit for obtaining a detection signal from the measured sample prepared by the sample preparation unit; and a controller for calculating an analysis result from the detection signal obtained by the detection unit. Bacteria analyzers for analyzing bacteria and solutions for use in sample analyzers are also described.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: February 16, 2010
    Assignee: Sysmex Corporation
    Inventors: Yasuyuki Kawashima, Masayuki Ikeda
  • Patent number: 7645594
    Abstract: A method of staining bacteria comprises: working a polymethine dye on a sample in the presence of a substance capable of reducing nitrite ions to stain bacteria in the sample. A method of detecting bacteria comprises the following steps of: (1) working a polymethine dye on a sample by a method as described above to stain bacteria in the sample, (2) introducing the thus treated sample into a detecting part of a flow cytometer and irradiating cells of the stained bacteria one by one with light to measure scattered light and fluorescent light emitted from each of the cells; and (3) discriminating the bacteria from other components in accordance with an intensity of a scattered light signal and an intensity of a fluorescent light signal or a pulse width reflecting the length of particles to count the bacteria.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: January 12, 2010
    Assignee: Sysmex Corporation
    Inventors: Yasuhiro Sakai, Yasuyuki Kawashima, Junya Inoue, Yoshiro Ikeuchi
  • Patent number: 7645714
    Abstract: Provided are SiO2—Al2O3-based or Li2O—Al2O3—SiO2-based crystallized glass that solves the cause of cracking and fracture in forming it into large-size shaped articles, that has homogeneous inner quality and that may be produced stably at high efficiency; and a method for producing it. The crystallized glass contains components of SiO2 and Al2O3, wherein the crystal precipitation peak temperature width obtained in differential thermal analysis of amorphous glass, a precursor thereof, is at least 22° C. Preferably, the total amount of the TiO2 component and the ZrO2 component in the crystallized glass is within a range of from 3.0 to less than 4.3%. FIG. 1 is referred to.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: January 12, 2010
    Assignee: Ohara Inc.
    Inventors: Yasuyuki Kawashima, Naoyuki Goto
  • Patent number: 7632683
    Abstract: A method for distinguishing erythrocytes in a biological specimen, includes preparing a sample liquid so as to cause damage to a cell membrane of yeast-like fungi without hemolyzing erythrocytes in a biological specimen and to stain the yeast-like fungi with a fluorescent dye; detecting a first information and a second information from a particle in the sample liquid, wherein the first information reflects a size of the particle and the second information reflects a degree of fluorescent staining of the particle; and distinguishing the erythrocytes from the yeast-like fungi based on the first information and second information detected. An apparatus, a reagent kit and a reagent for carrying out the method are also disclosed.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: December 15, 2009
    Assignee: Sysmex Corporation
    Inventors: Yasuyuki Kawashima, Yasuhiro Sakai
  • Patent number: 7582473
    Abstract: An apparatus for analyzing bacteria is described that includes an analyte sample preparing section for preparing an analyte sample from a specimen; a detector for detecting optical information from each particle in the analyte sample; and a controller for detecting non-fermentative bacteria on the basis of the detected optical information. A method for analyzing bacteria is also described.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: September 1, 2009
    Assignee: Sysmex Corporation
    Inventor: Yasuyuki Kawashima