Abstract: A non-contact temperature scanning system capable of high-speed determination of core body temperature TC by estimating a representative skin temperature TS of a subject from a thermal image. The system employs a biophysical model which considers heat transfer properties. In particular, the model takes into consideration of the ambient temperature TA and relative humidity Rh in addition to estimating TS from a thermal image. Once TS is determined, TC can be calculated based on the biophysical model which takes into consideration TA and Rh.