Patents by Inventor YAT HIN NICKI LEUNG

YAT HIN NICKI LEUNG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agents and methods for diagnosing fish allergy
    Patent number: 11656232
    Abstract: The present invention provides novel allergens isolated from grass carp Ctenopharyngodon idella, recombinant or modified polypeptides comprising such allergens, nucleic acids encoding the polypeptides as well as related compositions. Also provided are methods and kits for diagnosing fish allergy.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: May 23, 2023
    Assignee: The Chinese University of Hong Kong
    Inventors: Sze Yin Agnes Leung, Ting Fan Leung, Yat Hin Nicki Leung, Yee Yan Christine Wai
  • DIAGNOSTIC BIOMARKERS FOR SHRIMP ALLERGY
    Publication number: 20210382070
    Abstract: The present invention provides methods and compositions for improved diagnosis of shrimp allergies.
    Type: Application
    Filed: June 1, 2021
    Publication date: December 9, 2021
    Inventors: Ting Fan LEUNG, Yee Yan Christine Wai, Sze Yin Agnes Leung, Yat Hin Nicki Leung
  • NOVEL AGENTS AND METHODS FOR DIAGNOSING FISH ALLERGY
    Publication number: 20200191797
    Abstract: The present invention provides novel allergens isolated from grass carp Ctenopharyngodon Idella, recombinant or modified polypeptides comprising such allergens, nucleic acids encoding the polypeptides as well as related compositions. Also provided are methods and kits for diagnosing fish allergy.
    Type: Application
    Filed: September 30, 2019
    Publication date: June 18, 2020
    Inventors: Sze Yin Agnes Leung, Ting Fan Leung, Yat Hin Nicki Leung, Yee Yan Christine Wai
  • Met e 1 tropomyosin variants for use in allergen-specific immunotherapy
    Patent number: 10301365
    Abstract: The present invention provides isolated Met e 1 polypeptides and nucleic acids encoding the isolated polypeptides that can prevent and/or alleviate an allergic response to shellfish tropomyosin. The polypeptides are based on the shrimp tropomyosin Met e 1 protein and have been modified to act as hypoallergens. The Met e 1 hypoallergens have low to no IgE reactivity or allergenicity and are useful for prophylactic and/or therapeutic treatment of shellfish allergy in subject in need thereof.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: May 28, 2019
    Assignees: The Chinese University of Hong Kong, The Regents of the University of California
    Inventors: Ka Hou Chu, Patrick S. C. Leung, Yee Yan Christine Wai, Yat Hin Nicki Leung
  • Mimotopes of tropomyosin for use in immunotherapy for shellfish and/or arthropod allergy
    Patent number: 9920100
    Abstract: The present invention provides isolated peptides and nucleic acids encoding the isolated peptides that can modify a subject's immune response to tropomyosin. The isolated peptides correspond to peptide epitope mimics that are based on an invertebrate tropomyosin allergen, e.g., the shrimp tropomyosin Met e 1. Also provided are compositions and methods of use thereof to reduce, minimize or eliminate an allergic response to arthropods and/or shellfish.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: March 20, 2018
    Assignees: The Chinese University of Hong Kong, The Regents of the University of California
    Inventors: Patrick Leung, Ka Hou Chu, Yee Yan Wai, Yat Hin Nicki Leung
  • MET E 1 TROPOMYOSIN VARIANTS FOR USE IN ALLERGEN-SPECIFIC IMMUNOTHERAPY
    Publication number: 20170107265
    Abstract: The present invention provides isolated Met e 1 polypeptides and nucleic acids encoding the isolated polypeptides that can prevent and/or alleviate an allergic response to shellfish tropomyosin. The polypeptides are based on the shrimp tropomyosin Met e 1 protein and have been modified to act as hypoallergens. The Met e 1 hypoallergens have low to no IgE reactivity or allergenicity and are useful for prophylactic and/or therapeutic treatment of shellfish allergy in subject in need thereof.
    Type: Application
    Filed: October 3, 2016
    Publication date: April 20, 2017
    Inventors: Ka Hou CHU, Patrick S.C. Leung, Yee Yan Christine Wai, Yat Hin Nicki Leung
  • MIMOTOPES FOR USE IN IMMUNOTHERAPY FOR SHELLFISH AND/OR ARTHROPOD ALLERGY
    Publication number: 20160355555
    Abstract: The present invention provides isolated peptides and nucleic acids encoding the isolated peptides that can modify a subject's immune response to tropomyosin. The isolated peptides correspond to peptide epitope mimics that are based on an invertebrate tropomyosin allergen, e.g., the shrimp tropomyosin Met e 1. Also provided are compositions and methods of use thereof to reduce, minimize or eliminate an allergic response to arthropods and/or shellfish.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 8, 2016
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE CHINESE UNIVERSITY OF HONG KONG
    Inventors: PATRICK LEUNG, KA HOU CHU, YEE YAN WAI, YAT HIN NICKI LEUNG