Patents by Inventor Yat Or

Yat Or has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080039406
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: July 26, 2007
    Publication date: February 14, 2008
    Inventors: Yao-Ling Qiu, Tongzhu Liu, Yat Or, Ly Phan
  • Publication number: 20080027012
    Abstract: The present invention discloses compounds of formulae (I) and (II) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 31, 2008
    Inventors: Heejin Kim, Ly Tam Phan, Yat Or
  • Publication number: 20070299129
    Abstract: The present invention discloses compounds that are inhibitors of hormone-sensitive lipase. The present invention also discloses the use of the compounds and derivatives to inhibit hormone-sensitive lipase, various pharmaceutical compositions including the compounds, and methods of treatment using these compounds and compositions.
    Type: Application
    Filed: January 5, 2007
    Publication date: December 27, 2007
    Applicant: DEVIRIS INC.
    Inventors: Jean-Frederic Sauniere, Yat Or
  • Publication number: 20070299078
    Abstract: The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: June 26, 2007
    Publication date: December 27, 2007
    Inventors: Deqiang Niu, Dong Liu, Joel Moore, Guoyou Xu, Ying Sun, Yonghua Gai, Datong Tang, Yat Or, Zhe Wang
  • Publication number: 20070232554
    Abstract: The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: May 16, 2006
    Publication date: October 4, 2007
    Inventors: Yat Or, Deqiang Niu, Zhe Wang
  • Publication number: 20070161575
    Abstract: The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: November 20, 2006
    Publication date: July 12, 2007
    Applicant: Enanta Pharmaceuticals, Inc.
    Inventors: Zhenwei Miao, Ying Sun, Suanne Nakajima, Datong Tang, Zhe Wang, Yat Or
  • Publication number: 20070129290
    Abstract: The present invention relates to HDAC inhibitor derivatives, particularly derivatives of the free thiol of metabolites of the HDAC inhibitor FK228, pharmaceutical compositions thereof, and to methods of using such derivatives and pharmaceutical compositions thereof in the treatment of diseases associated with HDAC, in particular, tumor or cell proliferation diseases.
    Type: Application
    Filed: November 17, 2006
    Publication date: June 7, 2007
    Inventors: Yat Or, Gregory Verdine, Mitchell Keegan
  • Publication number: 20070082853
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: October 10, 2006
    Publication date: April 12, 2007
    Inventors: Yat Or, Guoqiang Wang, Tongzhu Liu, Ly Phan
  • Publication number: 20070060510
    Abstract: The present invention relates to compounds of Formula I or II, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: July 18, 2006
    Publication date: March 15, 2007
    Applicant: Enanta Pharmaceuticals, Inc.
    Inventors: Suanne Nakajima, Zhenwei Miao, Ying Sun, Datong Tang, Guoyou Xu, Brian Porter, Yat Or, Zhe Wang
  • Publication number: 20070021330
    Abstract: The present invention relates to compounds of Formula (I), or a pharmaceutically acceptable salt, ester, or prodrug, thereof, which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: May 19, 2004
    Publication date: January 25, 2007
    Applicant: Enanta Pharmaceuticals, Inc.
    Inventors: Frank Wu, Suanne Nakajima, Yat Or, Zhi-Hui Lu, Ying Sun, Zhenwei Miao, Zhe Wang
  • Publication number: 20060264386
    Abstract: The present invention provides pharmaceutical compositions and solid formulations comprising EP-013420 of form I, form II, form Ia, amorphous form and monohydrate and the methods of formulation preparations. The present invention provides methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment.
    Type: Application
    Filed: May 16, 2006
    Publication date: November 23, 2006
    Inventors: Rongqi Sun, Michelle Wang, Yat Or, Zhe Wang
  • Publication number: 20060252713
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: May 3, 2006
    Publication date: November 9, 2006
    Inventors: Yonghua Gai, Datong Tang, Ying Sun, Zhigang Chen, Yat Or, Zhe Wang
  • Publication number: 20060252710
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.
    Type: Application
    Filed: May 4, 2005
    Publication date: November 9, 2006
    Inventors: Guoqiang Wang, Ly Phan, Yat Or, Yao-Ling Qiu, Deqiang Niu, Yulin Peng, Marina Busuyek, Yanchun Wang, Suanne Nakajima
  • Publication number: 20060252712
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.
    Type: Application
    Filed: May 3, 2006
    Publication date: November 9, 2006
    Inventors: Guoqiang Wang, Ly Phan, Yat Or, Yao-ling Qiu, Deqiang Niu, Yulin Peng, Marina Busuyek, Yanchun Wang, Suanne Nakajima
  • Publication number: 20060247440
    Abstract: The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1.
    Type: Application
    Filed: August 17, 2005
    Publication date: November 2, 2006
    Inventors: Datong Tang, Yao-Ling Qiu, Heejin Kim, Yat Or, Zhe Wang
  • Publication number: 20060154881
    Abstract: The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: January 3, 2006
    Publication date: July 13, 2006
    Inventors: Yat Or, Ly Phan, Guoqiang Wang, Yanchun Wang, Yulin Peng
  • Publication number: 20060148731
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: December 13, 2005
    Publication date: July 6, 2006
    Inventors: Datong Tang, Yonghua Gai, Ying Sun, Zhigang Chen, Yat Or, Zhe Wang
  • Publication number: 20060142215
    Abstract: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: December 13, 2005
    Publication date: June 29, 2006
    Inventors: Datong Tang, Yonghua Gai, Ying Sun, Yat Or, Zhe Wang
  • Publication number: 20060142214
    Abstract: The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: December 6, 2005
    Publication date: June 29, 2006
    Inventors: Yat Or, Datong Tang, Ying Sun, Yonghua Gai, Guoyou Xu, Zhe Wang
  • Publication number: 20060122128
    Abstract: The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
    Type: Application
    Filed: December 7, 2004
    Publication date: June 8, 2006
    Inventors: Yat Or, Datong Tang, Yonghua Gai, Ying Sun, Guoyou Xu, Zhe Wang