Patents by Inventor Yatao SHI

Yatao SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Development of a Novel Mass Spectrometry-Based Method for Simultaneous Qualitative and Quantitative Protein Citrullination Analysis of Complex Biological Samples
    Publication number: 20210181206
    Abstract: The present invention discloses mass spectrometry (MS)-based methods and tagging reagents for qualitative and quantitative analysis of post-translational modified (PTM) proteins in biological and clinical samples. The present invention utilizes thiol-containing tagging reagents which are able to bind to or derivatize biomolecules, preferably post-translational modified (PTM) polypeptides such as citrullinated and homocitrullinated polypeptides. The tagging reagents are preferably biotin-derived tags able to react with a side chain of the modified polypeptides.
    Type: Application
    Filed: December 14, 2020
    Publication date: June 17, 2021
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Lingjun LI, Yatao SHI, Zihui LI