Abstract: A processing method of hydrogen peroxide aqueous solution includes the following steps. Base on a high catalytic trait of the catalase mixing aqueous solution relative to the hydrogen peroxide, aqueous solution and catalase mixing aqueous solution are provided into a semi-batch reactor that has a fixed capacity. Hydrogen peroxide aqueous solution/hydrogen peroxide aqueous solution with catalase is added into the semi-batch reactor, wherein the concentration of the hydrogen peroxide aqueous solution is from 0.5% to 90%. The hydrogen peroxide aqueous solution and the catalase mixing aqueous solution are reacted in the semi-batch reactor, and transformed into catalase mixing aqueous solution and hydrogen peroxide aqueous solution that has a concentration lower relative to the original concentration to effectively reduce the warming ratio and the boosting ratio of the semi-batch reactor for safely and effectively processing the hydrogen peroxide aqueous solution having a concentration from 0.5% to 90%.