Patents by Inventor YAU-YAU WAI

YAU-YAU WAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for extracting arterial input function and application thereof to dynamic contrast enhanced magnetic resonance imaging
    Patent number: 9131862
    Abstract: The present invention discloses a method for extracting AIF and an application thereof to DCE-MRI. The method comprises steps: contacting a target tissue with a contrast agent to obtain a plurality of images; using the plurality of images to work out the tissue concentration curve of the contrast agent in each voxel; calculating the purity of the tissue concentration curve of each voxel according to the tissue concentration curves; and extracting the voxel having the highest purity as the optimized arterial location; and extracting the tissue concentration curve of the voxel having the highest purity as the arterial input function. The extracted AIF is applied to a pharmacokinetic model to obtain associated pharmacokinetic parameters. The present invention not only improves the accuracy and reliability of the derived quantitative indexes but also promotes the efficiency of the quantitative analysis.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: September 15, 2015
    Assignee: Chang Gung University
    Inventors: Jiun-Jie Wang, Yu-Chun Lin, Tsung-Han Chan, Chong-Yung Chi, Shu-Hang Ng, Yau-Yau Wai
  • Method for the diagnosis of neurodegenerative disorder by using diffusion kurtosis imaging
    Patent number: 9031292
    Abstract: The invention relates to the use of diffusion kurtosis imaging (DKI) in the diagnosis of Parkinson Disease related neurodegenerative disorders, including (but not limited to) Parkinson's disease (PD) and Parkinson plus syndromes.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: May 12, 2015
    Assignee: Chang Gung University
    Inventors: Jiun-Jie Wang, Wey-Yil Lin, Chin-Song Lu, Yi-Hsin Weng, Ren-Hsiang Hsieh, Shu-Hang Ng, Yau-Yau Wai, Yung-Liang Wan
  • METHOD FOR EXTRACTING ARTERIAL INPUT FUNCTION AND APPLICATION THEREOF TO DYNAMIC CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING
    Publication number: 20140241604
    Abstract: The present invention discloses a method for extracting AIF and an application thereof to DCE-MRI. The method comprises steps: contacting a target tissue with a contrast agent to obtain a plurality of images; using the plurality of images to work out the tissue concentration curve of the contrast agent in each voxel; calculating the purity of the tissue concentration curve of each voxel according to the tissue concentration curves; and extracting the voxel having the highest purity as the optimized arterial location; and extracting the tissue concentration curve of the voxel having the highest purity as the arterial input function. The extracted AIF is applied to a pharmacokinetic model to obtain associated pharmacokinetic parameters. The present invention not only improves the accuracy and reliability of the derived quantitative indexes but also promotes the efficiency of the quantitative analysis.
    Type: Application
    Filed: February 28, 2013
    Publication date: August 28, 2014
    Applicant: CHANG GUNG UNIVERSITY
    Inventors: Jiun-Jie WANG, Yu-Chun LIN, Tsung-Han CHAN, Chong-Yung CHI, Shu-Hang NG, Yau-Yau WAI
  • METHOD FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDER BY USING DIFFUSION KURTOSIS IMAGING
    Publication number: 20130279771
    Abstract: The invention relates to the use of diffusion kurtosis imaging (DKI) in the diagnosis of Parkinson Disease related neurodegenerative disorders, including (but not limited to) Parkinson's disease (PD) and Parkinson plus syndromes.
    Type: Application
    Filed: April 19, 2012
    Publication date: October 24, 2013
    Applicant: CHANG GUNG UNIVERSITY
    Inventors: JIUN-JIE WANG, WEY-YIL LIN, CHIN-SONG LU, YI-HSIN WENG, REN-HSIANG HSIEH, SHU-HANG NG, YAU-YAU WAI, YUNG-LIANG WAN