Patents by Inventor Yawei CAI

Yawei CAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound with broad-spectrum antibacterial activity and its antibacterial composition
    Patent number: 12435031
    Abstract: A compound with broad-spectrum antibacterial activity and its antibacterial composition are provided. The compound with broad-spectrum antibacterial activity has formula (I), which are antibacterial drug source compounds with a broad antibacterial spectrum, good antibacterial activity, suitable in vivo pharmacokinetics, and significant in vivo therapeutic effects. Preferred compound BAB159 has good antibacterial activity against Staphylococcus, Clostridium perfringens, Enterococcus, Bacillus, Streptococcus, Haemophilus, Candida krusei, Aspergillus niger, and Trichophyton, which is comparable or better than the listed drugs. The combination of preferred compound BAB159 and polymyxin E exhibits significantly enhanced synergistic antibacterial activity, especially against multidrug-resistant strains.
    Type: Grant
    Filed: January 26, 2024
    Date of Patent: October 7, 2025
    Assignee: CHINA AGRICULTURAL UNIVERSITY
    Inventors: Jianzhong Shen, Kui Zhu, Xiaoyu Li, Kaixiang Zhou, Changsi Mao, Yawei Cai, Jijun Kang, Congming Wu, Xingyuan Cao, Dejun Liu
  • COMPOUND WITH BROAD-SPECTRUM ANTIBACTERIAL ACTIVITY AND ITS ANTIBACTERIAL COMPOSITION
    Publication number: 20250129013
    Abstract: A compound with broad-spectrum antibacterial activity and its antibacterial composition are provided. The compound with broad-spectrum antibacterial activity has formula (I), which are antibacterial drug source compounds with a broad antibacterial spectrum, good antibacterial activity, suitable in vivo pharmacokinetics, and significant in vivo therapeutic effects. Preferred compound BAB159 has good antibacterial activity against Staphylococcus, Clostridium perfringens, Enterococcus, Bacillus, Streptococcus, Haemophilus, Candida krusei, Aspergillus niger, and Trichophyton, which is comparable or better than the listed drugs. The combination of preferred compound BAB159 and polymyxin E exhibits significantly enhanced synergistic antibacterial activity, especially against multidrug-resistant strains.
    Type: Application
    Filed: January 26, 2024
    Publication date: April 24, 2025
    Inventors: Jianzhong SHEN, Kui ZHU, Xiaoyu LI, Kaixiang ZHOU, Changsi MAO, Yawei CAI, Jijun KANG, Congming WU, Xingyuan CAO, Dejun LIU