Abstract: A method, apparatus, system, and computer program code for policy-based enforcement in a data virtualization system is provided. Responsive to receiving a query, a computer identifies a virtual object among a set of connected objects that is represented by a set of data assets and their hierarchical relationships. The virtual object corresponds to a subset of the data assets. The computer identifies a subset of objects according to a cumulative transitive closure of the virtual object over the set of connected objects. The computer identifies a set of policies for the subset of objects. For each object in the subset of objects, the computer determines an intermediate decision according to set of policies, whereby a set of intermediate decisions is formed. The computer deterministically reconciles the set of intermediate decisions to generate a resolved decision. The computer provides access to the queried virtual objects based on the resolved decision.

Abstract: A method, apparatus, system, and computer program code for policy-based enforcement in a data virtualization system is provided. Responsive to receiving a query, a computer identifies a virtual object among a set of connected objects that is represented by a set of data assets and their hierarchical relationships. The virtual object corresponds to a subset of the data assets. The computer identifies a subset of objects according to a cumulative transitive closure of the virtual object over the set of connected objects. The computer identifies a set of policies for the subset of objects. For each object in the subset of objects, the computer determines an intermediate decision according to set of policies, whereby a set of intermediate decisions is formed. The computer deterministically reconciles the set of intermediate decisions to generate a resolved decision. The computer provides access to the queried virtual objects based on the resolved decision.

Abstract: Provided is a use of one or more MicroRNA genes selected from miRNAs of Family Let-7, miR-21 or miR-222 in the construction of tissue engineered nerves and in the repair of peripheral nerve defects. An outer and/or internal surface or pores of a tissue engineered nerve graft are coated or adsorbed with polymeric nanomicrospheres carrying a Let-7 family miRNA inhibitor, miR-21, or miR-222, or a mimetic thereof, wherein the polymeric material is composed of biocompatible fibronectin and heparin. The regeneration of peripheral nerves and the construction of tissue engineered nerves are promoted by regulating the expression of MicroRNA genes which can effectively promote the proliferation of primary Schwann cells cultured in vitro and have an anti-apoptotic effect on neuronal cells. In-vivo test proves that bridging of the tissue engineered nerve graft can facilitate the regeneration of peripheral nerves, thus being useful in the treatment of peripheral nerve injury.

Abstract: Provided is a use of one or more MicroRNA genes selected from miRNAs of Family Let-7, miR-21 or miR-222 in the construction of tissue engineered nerves and in the repair of peripheral nerve defects. An outer and/or internal surface or pores of a tissue engineered nerve graft are coated or adsorbed with polymeric nanomicrospheres carrying a Let-7 family miRNA inhibitor, miR-21, or miR-222, or a mimetic thereof, wherein the polymeric material is composed of biocompatible fibronectin and heparin. The regeneration of peripheral nerves and the construction of tissue engineered nerves are promoted by regulating the expression of MicroRNA genes which can effectively promote the proliferation of primary Schwann cells cultured in vitro and have an anti-apoptotic effect on neuronal cells. In-vivo test proves that bridging of the tissue engineered nerve graft can facilitate the regeneration of peripheral nerves, thus being useful in the treatment of peripheral nerve injury.