Abstract: An aerosol generating device includes: a shell; and an atomization assembly. The shell is formed with a first cavity and a second cavity, the first cavity for storing an aerosol generating substrate, the atomization assembly being disposed in the second cavity, the first cavity being in communication with the second cavity, the first cavity and the second cavity being disposed in parallel. The shell has side surfaces and a bottom surface that are connected, the side surfaces including a first side surface and a second side surface that are oppositely disposed, the first side surface being closer to the first cavity than the second side surface. The bottom surface and the first side surface are non-resting surfaces.

Abstract: An atomizer includes: an atomization base, the atomization base being provided with an airflow channel, the airflow channel having an air inlet hole, an air outlet hole, and an atomization cavity, the atomization cavity being respectively in communication with the air inlet hole and the air outlet hole, an airflow guiding structure being provided in the atomization cavity, the airflow guiding structure being disposed toward the air outlet hole; and an atomization core disposed on the atomization base and being in fluid communication with the atomization cavity, the atomization core including at least two heating elements, adjacent heating elements of the at least two heating elements being spaced apart.

Abstract: Provided herein are compounds comprising pyrrolobenzodiazepine (PBD)-based dimers and conjugates thereof. In some embodiments, a compound is of Formula (I): or a pharmaceutically acceptable salt, tautomer, solvate, stereoisomer, or isotopologue thereof.

Abstract: A system and process for adding a photorealistic rendering of a body of water to a virtual 3D scene or image and creating a video therefrom having interactive water effects. A region of water is added to an image by adding an area depicting the original scene as it would appear if reflected by still body of water. Then, the appearance of the added water region is distorted over a series of image frames in such a way as to simulate how the reflected scene would look if the surface of the water were in motion. The water can have dynamic waves and the user can interact with the water in numbers of ways, including generating ripples on the water surface and creating rain. In addition, these effects can be achieved at full screen resolution with the use of the latest graphics hardware by employing a texture shifting technique.

Abstract: A system and process for adding a photorealistic rendering of a body of water to a virtual 3D scene or image and creating a video therefrom having interactive water effects. A region of water is added to an image by adding an area depicting the original scene as it would appear if reflected by still body of water. Then, the appearance of the added water region is distorted over a series of image frames in such a way as to simulate how the reflected scene would look if the surface of the water were in motion. The water can have dynamic waves and the user can interact with the water in numbers of ways, including generating ripples on the water surface and creating rain. In addition, these effects can be achieved at full screen resolution with the use of the latest graphics hardware by employing a texture shifting technique.