Abstract: Disclosed herein are methods and compositions for treating or preventing bacterial infection. In particular, the methods and compositions are directed towards C. difficile infection. In particular aspects, the compositions are vaccines containing multimeric polypeptides containing portions of multiple toxins from bacteria. The polypeptides induce effective immune responses thus treating or preventing infection.

Abstract: Disclosed herein is a particulate filter for use in an emission treatment system of an internal combustion engine. The particulate filter provides high fresh filtration efficiency and has minimal to no impact on backpressures.

Abstract: The present invention relates to a novel human epidermal growth factor (hEGF)-trigger factor (TF) fusion protein and a use thereof. More particularly, the human epidermal growth factor (hEGF)-trigger factor (TF) fusion protein of the present invention has fused therein: a signal peptide of a Bacillus subtilis-derived xylanase; a human epidermal growth factor (hEGF); and an Escherichia coli-derived trigger factor (TF). Therefore, the present invention not only enhances the water solubility and expression rate of a target protein, but also notably enhances useful effects such as the effects of increasing skin cell growth and healing a wound, and thus may be widely used in various industries as an active ingredient for a functional cosmetic composition and a pharmaceutical composition.

Abstract: A device and a method for testing the rigidity and non-linear relationship of the coupling interface for cylindrical fitting including an axial loading assembly which is provided along a horizontal central line within a side wall of a frame test bench and contacting with the test-piece shaft via a steel ball, a radial loading assembly downward provided along a vertical central line of top board of the frame test bench, a tip of a perpendicular loading part of the radial loading assembly extending into the outer housing of the test-piece housing fixed on an upper plane of a bottom wall of the frame test bench, with the test-piece shaft and the test-piece housing fitted and connected to each other via a coupling interface for cylindrical fitting; a plurality of displacement sensors fixed on the test-piece housing, and test heads of respective displacement sensor assembly aiming at the test-piece shaft.

Abstract: A device and a method for testing the rigidity and non-linear relationship of the coupling interface for cylindrical fitting including an axial loading assembly which is provided along a horizontal central line within a side wall of a frame test bench and contacting with the test-piece shaft via a steel ball, a radial loading assembly downward provided along a vertical central line of top board of the frame test bench, a tip of a perpendicular loading part of the radial loading assembly extending into the outer housing of the test-piece housing fixed on an upper plane of a bottom wall of the frame test bench, with the test-piece shaft and the test-piece housing fitted and connected to each other via a coupling interface for cylindrical fitting; a plurality of displacement sensors fixed on the test-piece housing, and test heads of respective displacement sensor assembly aiming at the test-piece shaft.

Abstract: Disclosed is an operating position changeable loading apparatus with multi-axis joint movement used on machining center. The apparatus consists of a load-receiving test piece and a load-exerting component. Moving the load-exerting component and the load-receiving test piece to a preset loading position according to a multi-axis joint movement, with the displacement value measured by displacement sensors and the amount of simulated load measured by a force sensor of the loaded-exerting component, a stiffness of the load-exertion position under a simulated load can be derived. Changing the load-exertion position, repeating in sequence the previous steps, a stiffness distribution under the simulated load can be derived.

Abstract: Disclosed is a processing center multi-axis joint deflection loading apparatus comprising a load-receiving test piece and a load-exerting component. The load-exerting component is constituted by a steel ball, a cap, a ball socket, a bent board, a force sensor, a connection component A, and a connection component B. The connection component A is fixedly connected to a blade handle of the processing center; the blade handle is pulled tight within a bored hole on a main axle; and the connection component A is connected to a main housing via the connection component B.

Abstract: Consistent with the present invention, there is provided a circuit for extracting a common mode voltage of an input signal. The device may include an operational amplifier having an output, at least one negative input and at least one positive input, a first transistor, and a second transistor. A terminal of the first transistor may be coupled to the output of the operational amplifier. A terminal of the second transistor may be coupled to a terminal of the first transistor and the at least one positive input of the operational amplifier to create a negative feedback loop. The device may further include a common mode output, wherein the negative feedback loop extracts the common mode voltage of the input signal, the common mode voltage of the input signal being output at the common mode output. The device consistent with the present invention may provide the common mode voltage of the input signal without using any resistors, and while only occupying a small die area.

Abstract: Consistent with the present invention, there is provided a circuit for extracting a common mode voltage of an input signal. The device may include an operational amplifier having an output, at least one negative input and at least one positive input, a first transistor, and a second transistor. A terminal of the first transistor may be coupled to the output of the operational amplifier. A terminal of the second transistor may be coupled to a terminal of the first transistor and the at least one positive input of the operational amplifier to create a negative feedback loop. The device may further include a common mode output, wherein the negative feedback loop extracts the common mode voltage of the input signal, the common mode voltage of the input signal being output at the common mode output. The device consistent with the present invention may provide the common mode voltage of the input signal without using any resistors, and while only occupying a small die area.