Abstract: Provided are an analytic method to provide information needed for the diagnosis of patients with ovarian cancer resistant to paclitaxel which is an anticancer drug widely used in the treatment of ovarian cancer, the method comprising a step of measuring the expression level of a gene encoding at least one deubiquitinating enzyme selected from the group consisting of USP3, USP9X, USP26, USP34, COPS5, OTUD6A, and OTUD7A, in a tumor cell sample externally discharged from an ovarian cancer patient; and a kit for diagnosing ovarian cancer resistant to paclitaxel, the kit comprising a molecule capable of measuring the expression level of a gene encoding the protein.

Abstract: An electric stimulator for alpha-wave derivation is characterized in that frequency selected from a range of 1 Hz to 50 Hz, preferably, 7 Hz to 14 Hz, and an output voltage are applied to auricle of a patient's ears to derive alpha-waves, and that cycle and intensity of stimulation are varied depending upon body temperature and blood sugar. Prompt reaction may be obtained by directly applying the voltage to the ears, and the reaction may continue when stimulation is extended. In addition, it is suitable to treat various diseases having common cause due to stress or arousal reaction in the human body.

Abstract: An electric stimulator for alpha-wave derivation is characterized in that frequency selected from a range of 1 Hz to 50 Hz, preferably, 7 Hz to 14 Hz, and an output voltage are applied to auricle of a patient's ears to derive alpha-waves, and that cycle and intensity of stimulation are varied depending upon body temperature and blood sugar. Prompt reaction may be obtained by directly applying the voltage to the ears, and the reaction may continue when stimulation is extended. In addition, it is suitable to treat various diseases having common cause due to stress or arousal reaction in the human body.