Patents by Inventor Yee Chen

Yee Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240307531
    Abstract: A method of treating pulmonary metastasis of osteosarcoma cells (pOSs) in a subject in need thereof includes administering to the subject a therapeutically effective amount of an agent that interferes with VCAM-1/?4?1 signaling between pOSs expressing VCAM-1 and pulmonary macrophages (MACs) expressing ?4?1.
    Type: Application
    Filed: February 27, 2024
    Publication date: September 19, 2024
    Inventors: Alex Yee-Chen Huang, Jay T. Myers
  • Patent number: 12046834
    Abstract: An antenna for use in a distributed antenna system includes: (a) a feeding circuit on a first side of a first dielectric defining a planar edge perpendicular to the first side, a coplanar waveguide comprising a signal feed and a signal return coplanar with and interfittingly apart from the signal feed; (b) a radiator circuit on a second side of a second dielectric, a monopole radiator and a radiator return being copolanar and spaced apart from each other, the first dielectric capacitively coupling the signal feed to the monopole radiator; and (c) an edge connection along the planar edge for electrically connecting the signal return to the radiator return. A cover encloses the feeding circuit, including its impedance matching, in a water-resistant enclosure. The antenna ceiling-mounts indoors, is coated with a fire-resistant coating, and is operable at VHF (132-174 MHz), UHF (350-520 MHz), and 698-960 MHz.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: July 23, 2024
    Assignee: Norsat International Inc.
    Inventors: Yee Chen, Tong Li, Yazi Cao
  • Patent number: 11911468
    Abstract: A method of treating pulmonary metastasis of osteosarcoma cells (pOSs) in a subject in need thereof includes administering to the subject a therapeutically effective amount of an agent that interferes with VCAM-1/?4?1 signaling between pOSs expressing VCAM-1 and pulmonary macrophages (MACs) expressing ?4?1.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: February 27, 2024
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Alex Yee-Chen Huang, Jay T. Myers
  • Patent number: 11884730
    Abstract: A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: January 30, 2024
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Alex Yee-Chen Huang, Agne Petrosiute
  • Patent number: 11734246
    Abstract: Disclosed herein are systems and method for multiplexing data of an underlying index. In an exemplary aspect, an index handler may: search for a data file in a plurality of data buckets associated with an index, wherein at least one respective data bucket of a plurality of data buckets is attached to a respective slot of a plurality of slots; identify, based on the searching, a first data bucket of the plurality of data buckets that comprises the data file; in response to determining that the first data bucket is not attached to any of the plurality of slots, attach the first data bucket to a first slot of the plurality of slots; and enable access to the data file via the first data bucket attached to the first slot.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: August 22, 2023
    Assignee: Acronis International GmbH
    Inventors: Alexander Andreev, Sergey Onuchin, Hiten Gajjar, Dulitha Gunasekera, Dian Bakti, Prabhuraj Reddy, Yee Chen Lim, Serguei Beloussov, Stanislav Protasov
  • Publication number: 20230192863
    Abstract: A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1.
    Type: Application
    Filed: February 10, 2023
    Publication date: June 22, 2023
    Inventors: Muta Abiff, Alex Yee-Chen Huang
  • Publication number: 20220311139
    Abstract: An antenna for use in a distributed antenna system is provided. The antenna includes: (a) a feeding circuit on a first side of a first dielectric defining an edge perpendicular to the first side, a coplanar waveguide comprising a signal feed and a signal return coplanar with and interfittedly apart from the signal feed; (b) a radiator circuit on a second side of a second dielectric, a monopole radiator and a radiator return being copolanar and spaced apart from each other, the first dielectric capacitively coupling the signal feed to the monopole radiator; and (c) an edge connection along the edge for electrically connecting the signal return to the radiator return. A cover encloses the feeding circuit, including its impedance matching, in a water-resistant enclosure. The antenna ceiling-mounts indoors, is coated with a fire-resistant coating, and is operable at VHF (132-174 MHz), UHF (350-520 MHz), and 698-960 MHz.
    Type: Application
    Filed: May 28, 2021
    Publication date: September 29, 2022
    Applicant: Norsat International Inc.
    Inventors: Yee Chen, Tong Li, Yazi Cao
  • Publication number: 20220222234
    Abstract: Disclosed herein are systems and method for multiplexing data of an underlying index. In an exemplary aspect, an index handler may: search for a data file in a plurality of data buckets associated with an index, wherein at least one respective data bucket of a plurality of data buckets is attached to a respective slot of a plurality of slots; identify, based on the searching, a first data bucket of the plurality of data buckets that comprises the data file; in response to determining that the first data bucket is not attached to any of the plurality of slots, attach the first data bucket to a first slot of the plurality of slots; and enable access to the data file via the first data bucket attached to the first slot.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Inventors: Alexander Andreev, Sergey Onuchin, Hiten Gajjar, Dulitha Gunasekera, Dian Bakti, Prabhuraj Reddy, Yee Chen Lim, Serguei Beloussov, Stanislav Protasov
  • Publication number: 20220169735
    Abstract: A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1.
    Type: Application
    Filed: September 21, 2021
    Publication date: June 2, 2022
    Inventors: Alex Yee-Chen Huang, Agne Petrosiute
  • Patent number: 11321295
    Abstract: Disclosed herein are systems and method for multiplexing data of an underlying index. In an exemplary aspect, an index handler may generate a plurality of slots and a plurality of data buckets for a traditional index. The index handler may receive, from a software application, a request to access a data file. The index handler may determine whether any slot of the plurality of slots is attached to a respective data bucket of the plurality of data buckets comprising the data file. In response to determining that a first slot of the plurality of slots is attached to a first data bucket comprising the data file, the index handler may enable, via the first data bucket attached to the first slot, access to the data file to the software application.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: May 3, 2022
    Assignee: Acronis International GmbH
    Inventors: Alexander Andreev, Sergey Onuchin, Hiten Gajjar, Dulitha Gunasekera, Dian Bakti, Prabhuraj Reddy, Yee Chen Lim, Serguei Beloussov, Stanislav Protasov
  • Publication number: 20210393774
    Abstract: A method of treating pulmonary metastasis of osteosarcoma cells (pOSs) in a subject in need thereof includes administering to the subject a therapeutically effective amount of an agent that interferes with VCAM-1/?4?1 signaling between pOSs expressing VCAM-1 and pulmonary macrophages (MACs) expressing ?4?1.
    Type: Application
    Filed: May 4, 2021
    Publication date: December 23, 2021
    Inventors: Alex Yee-Chen Huang, Jay T. Myers
  • Patent number: 11124571
    Abstract: A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: September 21, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Alex Yee-Chen Huang, Agne Petrosiute
  • Publication number: 20210149863
    Abstract: Disclosed herein are systems and method for multiplexing data of an underlying index. In an exemplary aspect, an index handler may generate a plurality of slots and a plurality of data buckets for a traditional index. The index handler may receive, from a software application, a request to access a data file. The index handler may determine whether any slot of the plurality of slots is attached to a respective data bucket of the plurality of data buckets comprising the data file. In response to determining that a first slot of the plurality of slots is attached to a first data bucket comprising the data file, the index handler may enable, via the first data bucket attached to the first slot, access to the data file to the software application.
    Type: Application
    Filed: November 14, 2019
    Publication date: May 20, 2021
    Inventors: Alexander Andreev, Sergey Onuchin, Hiten Gajjar, Dulitha Gunasekera, Dian Bakti, Prabhuraj Reddy, Yee Chen Lim, Serguei Beloussov, Stan isl av Protasov
  • Patent number: 10994009
    Abstract: A method of treating pulmonary metastasis of osteosarcoma cells (pOSs) in a subject in need thereof includes administering to the subject a therapeutically effective amount of an agent that interferes with VCAM-1/?4?1 signaling between pOSs expressing VCAM-1 and pulmonary macrophages (MACs) expressing ?4?1.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: May 4, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Alex Yee-Chen Huang, Jay T. Myers
  • Patent number: 10941199
    Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: March 9, 2021
    Assignee: Genentech, Inc.
    Inventors: Liping L. Sun, Yvonne Man-Yee Chen, Mark S. Dennis, Allen J. Ebens, Jr., Andrew Polson
  • Publication number: 20190194330
    Abstract: A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1.
    Type: Application
    Filed: May 24, 2017
    Publication date: June 27, 2019
    Inventors: Alex Yee-Chen Huang, Agne Petrosiute
  • Publication number: 20180369372
    Abstract: A method of treating pulmonary metastasis of osteosarcoma cells (pOSs) in a subject in need thereof includes administering to the subject a therapeutically effective amount of an agent that interferes with VCAM-1/?4?1 signaling between pOSs expressing VCAM-1 and pulmonary macrophages (MACs) expressing ?4?1.
    Type: Application
    Filed: June 26, 2018
    Publication date: December 27, 2018
    Inventors: Alex Yee-Chen Huang, Jay T. Myers
  • Publication number: 20180327492
    Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
    Type: Application
    Filed: April 19, 2018
    Publication date: November 15, 2018
    Applicant: Genentech, Inc.
    Inventors: Liping L. Sun, Yvonne Man-Yee Chen, Mark S. Dennis, Allen J. Ebens, JR., Andrew Polson
  • Patent number: 9975949
    Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: May 22, 2018
    Assignee: Genentech, Inc.
    Inventors: Liping L. Sun, Yvonne Man-Yee Chen, Mark S. Dennis, Allen J. Ebens, Jr., Andrew Polson
  • Publication number: 20170369564
    Abstract: Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.
    Type: Application
    Filed: January 15, 2016
    Publication date: December 28, 2017
    Applicant: Genentech, Inc.
    Inventors: Manuel Baca, James A. Wells, Leonard G. Presta, Henry B. Lowman, Yvonne Man-yee Chen