Patents by Inventor Yeelana Shen

Yeelana Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Somatostatin-dopamine chimeric analogs
    Patent number: 9731027
    Abstract: The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: August 15, 2017
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen, Sun Hyuk Kim
  • Somatostatin-dopamine chimeric analogs
    Patent number: 9603942
    Abstract: The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: March 28, 2017
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen
  • Somatostatin-Dopamine Chimeric Analogs
    Publication number: 20150290330
    Abstract: The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
    Type: Application
    Filed: October 31, 2013
    Publication date: October 15, 2015
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: Zheng Xin DONG, Yeelana SHEN, Sun Hyuk Kim
  • Ghrelin analogs
    Patent number: 9133261
    Abstract: The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: September 15, 2015
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen
  • SOMATOSTATIN-DOPAMINE CHIMERIC ANALOGS
    Publication number: 20150148522
    Abstract: The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
    Type: Application
    Filed: February 5, 2015
    Publication date: May 28, 2015
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: Zheng Xin DONG, Yeelana SHEN
  • Somatostatin-dopamine chimeric analogs
    Patent number: 8952128
    Abstract: The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: February 10, 2015
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen, Sun Hyuk Kim
  • Ghrelin Analogs
    Publication number: 20140135260
    Abstract: The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: Zheng Xin DONG, Yeelana SHEN
  • Somatostatin-Dopamine Chimeric Analogs
    Publication number: 20140121354
    Abstract: The present invention relates to novel somatostatin-dopamine chimeric analogs and their therapeutic uses for the inhibition, prevention, and/or treatment of neoplasia, neuroendocrine tumors, Cushing's disease/syndrome, and other conditions.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 1, 2014
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: ZHENG XIN DONG, YEELANA SHEN, SUN HYUK KIM
  • Ghrelin analogs
    Patent number: 8633151
    Abstract: The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: January 21, 2014
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen
  • Analogues of glucose-dependent insulinotropic polypeptide
    Patent number: 8450266
    Abstract: There is provided a novel series of analogues of glucose-dependent insulinotropic polypeptide compounds, pharmaceutical compositions containing said compounds, and the use of said compounds as GIP-receptor agonists or antagonists for treatment of GIP-receptor mediated conditions, such as non-insulin dependent diabetes mellitus and obesity.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: May 28, 2013
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen, Daniel B. DeOliveira
  • Analogs of ghrelin
    Patent number: 8258094
    Abstract: The invention comprises peptidyl analogs according to formulae (I) or (II) as depicted below: (R2R3)-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13- A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25- A-26-A27-A28-R1 wherein the definitions of A1 to A28 and R1 to R3 are provided for in the specification for each of formulae (I) and (II), pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising an effective amount of a compound of formula (I), that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: September 4, 2012
    Assignee: IPSEN Pharma S.A.S.
    Inventors: Zheng Xin Dong, Michael DeWitt Culler, Yeelana Shen, Jeanne Mary Comstock
  • Peptide-cytotoxic conjugates
    Patent number: 8236762
    Abstract: The invention features targeted cytotoxic compounds and methods relating to their therapeutic use for the treatment of neoplasia and other conditions.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: August 7, 2012
    Assignee: IPSEN Pharma S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen, Michael DeWitt Culler, Christophe Alain Thurieau, Jundong Zhang, Sun Hyuk Kim
  • Growth hormone secretagogues
    Patent number: 8138218
    Abstract: A family of peptides and peptidomimetic compounds useful as GHS analogs according to either formula (I) or (II) as depicted below: or a pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: March 20, 2012
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Zheng Xin Dong, John S. Eynon, Yeelana Shen
  • ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE
    Publication number: 20110136724
    Abstract: There is provided a novel series of analogues of glucose-dependent insulinotropic polypeptide compounds, pharmaceutical compositions containing said compounds, and the use of said compounds as GIP-receptor agonists or antagonists for treatment of GIP-receptor mediated conditions, such as non-insulin dependent diabetes mellitus and obesity.
    Type: Application
    Filed: August 7, 2009
    Publication date: June 9, 2011
    Inventors: Zheng Xin Dong, Yeelana Shen, Daniel B. DeOliveira
  • PEPTIDE-CYTOTOXIC CONJUGATES
    Publication number: 20100113367
    Abstract: The invention features targeted cytotoxic compounds and methods relating to their therapeutic use for the treatment of neoplasia and other conditions.
    Type: Application
    Filed: October 17, 2007
    Publication date: May 6, 2010
    Inventors: Zheng Xin Dong, Yeelana Shen, Michael DeWitt Culler, Christophe Alain Thurieau, Jundong Zhang, Sun Hyuk Kim
  • Ghrelin analogs
    Publication number: 20100069299
    Abstract: The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
    Type: Application
    Filed: June 16, 2009
    Publication date: March 18, 2010
    Inventors: Zheng Xin Dong, Yeelana Shen
  • Analogs of Ghrelin
    Publication number: 20090156483
    Abstract: The invention comprises peptidyl analogs according to formulae (I) or (II) as depicted below: (R2R3)-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13- A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25- A-26-A27-A28-R1 wherein the definitions of A1 to A28 and R1 to R3 are provided for in the specification for each of formulae (I) and (II), pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising an effective amount of a compound of formula (I), that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
    Type: Application
    Filed: March 28, 2008
    Publication date: June 18, 2009
    Inventors: Zheng Xin Dong, Michael DeWitt Culler, Yeelana Shen, Jeanne Mary Comstock
  • Growth Hormone Secretagogues
    Publication number: 20090131478
    Abstract: A family of peptides and peptidomimetic compounds useful as GHS analogs according to either formula (I) or (II) as depicted below: or a pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification.
    Type: Application
    Filed: July 24, 2006
    Publication date: May 21, 2009
    Inventors: Zheng Xin Dong, John S. Eynon, Yeelana Shen
  • Imidazolyl derivatives
    Publication number: 20040002531
    Abstract: The present invention is directed to imidazolyl derivatives of formula (II), wherein the variables are defined in the specification, which are useful as prenyl transeferase inhibitors.
    Type: Application
    Filed: January 21, 2003
    Publication date: January 1, 2004
    Applicant: Societe de Conseils de Recherches et D'Application Scientefiques, S.A.S., a France corporation
    Inventors: Zheng Xin Dong, Yeelana Shen
  • Imidazolyl derivatives
    Patent number: 6509336
    Abstract: The present invention is directed to imidazolyl derivatives of formula (II), wherein the variables are defined in the specification, which are useful as prenyl transeferase inhibitors.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: January 21, 2003
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques, S.A.S.
    Inventors: Zheng Xin Dong, Yeelana Shen