Patents by Inventor Yefeng YAO

Yefeng YAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12276625
    Abstract: The present invention is directed to a method of species identification and quality detection of liquid-like samples based on nuclear magnetic resonance technology. In this invention, a two-dimensional relaxation signal containing the 1H T1 and T2 relaxation properties of liquid-like samples is obtained by applying a composite pulse sequence to samples, and from this a fingerprint spectrum is established. The fingerprint spectrum can be associated with the essential characteristics of the tested sample, thus can be used to distinguish a specific liquid-like sample from the others.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: April 15, 2025
    Assignee: EAST CHINA NORMAL UNIVERSITY
    Inventors: Yefeng Yao, Jiachen Wang, Yi Li, Jiaxiang Xin, Jing Zhu, Xuelu Wang
  • Patent number: 12044640
    Abstract: A method uses the nuclear spin singlet of three hydrogen atoms on the dopamine benzene ring to achieve selective detection of dopamine signals in a complicated system. The present invention is based on magnetic resonance technology to detect dopamine, has good accuracy, sensitivity and selectivity, can accurately detect the signal of dopamine from the complicated system, and the interference of signals of other substances are well eliminated. Meanwhile, the present invention further has the advantages of simple operation and non-intervention, can be used for monitoring the content and distribution of the dopamine in a living body, and has important application value in the fields of biology and medicine.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: July 23, 2024
    Assignee: EAST CHINA NORMAL UNIVERSITY
    Inventors: Yefeng Yao, Jiaxiang Xin, Huixia Liu, Daxiu Wei
  • Publication number: 20240182920
    Abstract: Provided is a method for transducing cells with a viral vector, and further provided are cells obtained through recombination or heterologous gene transduction and compositions thereof, and a method for using same in adoptive immunotherapy. Under the premise of not affecting the expression of recombinant nucleic acid, the method shortens the activation and transduction time during the preparation process of genetically engineered cells.
    Type: Application
    Filed: January 22, 2021
    Publication date: June 6, 2024
    Inventors: Huamao WANG, Huiping GAO, Xiao TONG, Yefeng YAO, Yinyu ZHU, Zonghai LI
  • Publication number: 20230075079
    Abstract: The present invention discloses a method of species identification and quality detection of liquid-like samples based on nuclear magnetic resonance technology. In this invention, a two-dimensional relaxation signal containing the 1H T1 and T2 relaxation properties of liquid-like samples is obtained by applying a specially designed composite pulse sequence to liquid-like samples, and a fingerprint spectrum from this signal is established. The fingerprint spectrum can be associated with the essential characteristics of the tested sample, thus can be used to distinguish a specific liquid-like sample from the others. The fingerprint spectrum can be easily converted into a digital form, which is not only suitable for constructing big data of fingerprint spectrum for liquid-like samples, but also can be used for quality detection and authenticity judgment of liquid-like samples based on artificial intelligence.
    Type: Application
    Filed: April 23, 2021
    Publication date: March 9, 2023
    Applicant: EAST CHINA NORMAL UNIVERSITY
    Inventors: Yefeng YAO, Jiachen WANG, Yi LI, Jiaxiang XIN, Jing ZHU, Xuelu WANG
  • Publication number: 20220003697
    Abstract: The present invention discloses a method for selectively detecting dopamine based on magnetic resonance nuclear spin singlet state. The method uses the nuclear spin singlet of three hydrogen atoms on the dopamine benzene ring to achieve selective detection of dopamine signals in a complicated system. The present invention is based on magnetic resonance technology to detect dopamine, has good accuracy, sensitivity and selectivity, can accurately detect the signal of dopamine from the complicated system, and the interference of signals of other substances are well eliminated. Meanwhile, the present invention further has the advantages of simple operation and non-intervention, can be used for monitoring the content and distribution of the dopamine in a living body, and has important application value in the fields of biology and medicine.
    Type: Application
    Filed: November 29, 2019
    Publication date: January 6, 2022
    Applicant: EAST CHINA NORMAL UNIVERSITY
    Inventors: Yefeng YAO, Jiaxiang XIN, Huixia LIU, Daxiu WEI