Patents by Inventor Yehia M. Ibrahim
Yehia M. Ibrahim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10497552Abstract: An ion manipulation device comprises a plurality of electrode rings arranged longitudinally adjacent to each other and defining a central axis therethrough. At least one electrode ring comprises a plurality of electrodes arranged in a first planar pattern. Electrodes are configured to periodically receive a voltage to generate a circular traveling wave that rotates around the electrodes of each electrode ring to confine ions within an interior of the apparatus.Type: GrantFiled: August 14, 2018Date of Patent: December 3, 2019Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Aneesh Prabhakaran, Sandilya V. B. Garimella, Richard D. Smith, Ailin Li
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Patent number: 10466202Abstract: Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially according to their mobilities. A second intermittent traveling wave is applied for regrouping or merging the dispersed ion packets into a lesser number of trapping regions with narrower peaks. The ions packets are compressed into the narrower peak regions by varying a duty cycle of the intermittent traveling wave.Type: GrantFiled: July 3, 2018Date of Patent: November 5, 2019Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Sandilya Garimella, Richard D. Smith
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Patent number: 10460920Abstract: An apparatus includes a flexible ion conduit extending between an input end situated to receive ions and an output end to define an ion passageway having an axis, the flexible ion conduit including an inner conduit portion having an inner surface facing the interior ion passageway and having a plurality of RF electrodes adjacently situated to receive RF voltages that are out of phase with respect to each other to direct the received ions away from the inner surface and into the ion passageway.Type: GrantFiled: June 26, 2018Date of Patent: October 29, 2019Assignee: Battelle Memorial InstituteInventors: Richard D. Smith, Sandilya V. B. Garimella, Yehia M. Ibrahim
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Patent number: 10424471Abstract: An apparatus includes a flexible ion conduit extending between an input end situated to receive ions and an output end to define an ion passageway having an axis, the flexible ion conduit including an inner conduit portion having an inner surface facing the interior ion passageway and having a plurality of RF electrodes adjacently situated to receive RF voltages that are out of phase with respect to each other to direct the received ions away from the inner surface and into the ion passageway.Type: GrantFiled: June 26, 2018Date of Patent: September 24, 2019Assignee: Battelle Memorial InstituteInventors: Richard D. Smith, Sandilya V. B. Garimella, Yehia M. Ibrahim
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Patent number: 10424474Abstract: Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a non-planar surface having a first, second and third region. An inner arrays of electrodes is positioned on the first region. A first set of electrodes of the inner array of electrodes is configured to receive RF voltages and generate a first potential upon the receipt of the RF voltage. A first and second outer arrays of electrodes are coupled to the second and third region, respectively. The first and second outer arrays are configured to receive a first DC voltage and generate a second potential upon the receipt of the first DC voltages. The first and second generated potential manipulate movement of ions.Type: GrantFiled: May 2, 2016Date of Patent: September 24, 2019Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Sandilya V. B. Garimella, Richard D. Smith
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Publication number: 20190198305Abstract: An apparatus includes a first pair of opposing electrode arrangements that confine ions between them in a portion of a confinement volume inwardly laterally in a first confinement direction with respect to a longitudinal ion propagation direction, each opposing electrode arrangement including an arrangement of RF electrodes situated to receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes of the arrangement of RF electrodes so as to provide the confining of ions between the first pair of opposing electrode arrangements, and a second pair of opposing electrode arrangements that confine the ions between the second pair in the confinement volume inwardly laterally in a second confinement direction that complements the first confinement direction, each opposing electrode arrangement of the second pair including an arrangement of RF electrodes that receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes.Type: ApplicationFiled: February 28, 2019Publication date: June 27, 2019Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Richard D. Smith
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Patent number: 10332723Abstract: Apparatus include a plurality of electrode arrangements spaced apart from each other opposite an ion propagation axis and defining an ion transfer channel that extends along the ion propagation axis that tapers between an input end that is situated to receive ions and an output end that is situated to couple the received ions to an input end of an ion guide. Methods include positioning a plurality of electrode arrangements at oblique angles opposite an ion propagation axis so as to form a ion transfer channel that tapers between an input end and an output end, and coupling the output end of the ion transfer channel to an input end of an ion optical element so as to direct ions in the ion transfer channel into the ion optical element. Related systems are also disclosed.Type: GrantFiled: December 20, 2017Date of Patent: June 25, 2019Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Richard D. Smith
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Publication number: 20190189393Abstract: Apparatus include a plurality of electrode arrangements spaced apart from each other opposite an ion propagation axis and defining an ion transfer channel that extends along the ion propagation axis that tapers between an input end that is situated to receive ions and an output end that is situated to couple the received ions to an input end of an ion guide. Methods include positioning a plurality of electrode arrangements at oblique angles opposite an ion propagation axis so as to form a ion transfer channel that tapers between an input end and an output end, and coupling the output end of the ion transfer channel to an input end of an ion optical element so as to direct ions in the ion transfer channel into the ion optical element. Related systems are also disclosed.Type: ApplicationFiled: December 20, 2017Publication date: June 20, 2019Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Richard D. Smith
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Patent number: 10317364Abstract: Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation.Type: GrantFiled: August 15, 2016Date of Patent: June 11, 2019Assignee: Battelle Memorial InstituteInventors: Venkata B S Garimella, Ahmed M. Hamid, Yehia M. Ibrahim, Richard D. Smith
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Publication number: 20190108990Abstract: A method of manipulating ions comprises injecting ions between a first surface and a second surface positioned parallel to and spaced apart from each other and defining a central axis therebetween, wherein the first surface comprises first outer electrodes coupled to the first surface and a first inner array of electrodes coupled to the first surface and positioned between the first outer electrodes, wherein the second surface comprises second outer electrodes coupled to the second surface and a second inner array of electrodes coupled to the second surface and positioned between the second outer electrodes, and applying a frequency modulated RF voltage to at least one electrode of the first inner array of electrodes or the second inner array of electrodes to confine ions between the first surface and the second surface and to guide ions between the first surface and the second surface along the central axis.Type: ApplicationFiled: November 16, 2018Publication date: April 11, 2019Applicant: Battelle Memorial InstituteInventors: Aneesh Prabhakaran, Yehia M. Ibrahim, Sandilya V. B. Garimella
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Publication number: 20190103261Abstract: A switch for coupling a first ion manipulation device to a second ion manipulation device comprises a first surface and a second surface, at least one first electrode coupled to each of the first and second surface and configured to receive a first voltage and generate a first potential, and at least one second electrode coupled to each of the first and second surface and configured to receive a second voltage and generate a second potential, wherein the first potential inhibits the motion of ions along a first direction and the second potential inhibits the motion of ions along a second direction different from the first direction.Type: ApplicationFiled: July 11, 2018Publication date: April 4, 2019Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Richard D. Smith
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Patent number: 10224194Abstract: An apparatus includes a first pair of opposing electrode arrangements that confine ions between them in a portion of a confinement volume inwardly laterally in a first confinement direction with respect to a longitudinal ion propagation direction, each opposing electrode arrangement including an arrangement of RF electrodes situated to receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes of the arrangement of RF electrodes so as to provide the confining of ions between the first pair of opposing electrode arrangements, and a second pair of opposing electrode arrangements that confine the ions between the second pair in the confinement volume inwardly laterally in a second confinement direction that complements the first confinement direction, each opposing electrode arrangement of the second pair including an arrangement of RF electrodes that receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes.Type: GrantFiled: September 8, 2016Date of Patent: March 5, 2019Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Richard D. Smith
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Publication number: 20190057852Abstract: An ion manipulation device comprises a plurality of electrode rings arranged longitudinally adjacent to each other and defining a central axis therethrough. At least one electrode ring comprises a plurality of electrodes arranged in a first planar pattern. Electrodes are configured to periodically receive a voltage to generate a circular traveling wave that rotates around the electrodes of each electrode ring to confine ions within an interior of the apparatus.Type: ApplicationFiled: August 14, 2018Publication date: February 21, 2019Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Aneesh Prabhakaran, Sandilya V.B. Garimella, Richard D. Smith, Ailin Li
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Publication number: 20190056352Abstract: Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially according to their mobilities. A second intermittent traveling wave is applied for regrouping or merging the dispersed ion packets into a lesser number of trapping regions with narrower peaks. The ions packets are compressed into the narrower peak regions by varying a duty cycle of the intermittent traveling wave.Type: ApplicationFiled: July 3, 2018Publication date: February 21, 2019Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Sandilya Garimella, Richard D. Smith
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Publication number: 20190004011Abstract: Methods and apparatuses for ion manipulations, including ion trapping, transfer, and mobility separations, using traveling waves (TW) formed by continuous alternating current (AC) are disclosed. An apparatus for ion manipulation includes a surface to which are coupled a first plurality of continuous electrodes and a second plurality of segmented electrodes. The second plurality of segmented electrodes is arranged in longitudinal sets between or adjacent to the first plurality of electrodes. An RF voltage applied to adjacent electrodes of the first plurality of electrodes is phase shifted by approximately 180° to confine ions within the apparatus. An AC voltage waveform applied to adjacent electrodes within a longitudinal set of the second plurality of segmented electrodes is phase shifted on the adjacent electrodes by 1°-359° to move ions longitudinally through the apparatus for separation.Type: ApplicationFiled: August 15, 2016Publication date: January 3, 2019Applicant: Battelle Memorial InstituteInventors: Venkata BS Garimella, Ahmed M. Hamid, Yehia M. Ibrahim, Richard D. Smith
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Publication number: 20180254178Abstract: Methods and devices for ion separations or manipulations in gas phase are disclosed. The device includes a non-planar surface having a first, second and third region. An inner arrays of electrodes is positioned on the first region. A first set of electrodes of the inner array of electrodes is configured to receive RF voltages and generate a first potential upon the receipt of the RF voltage. A first and second outer arrays of electrodes are coupled to the second and third region, respectively. The first and second outer arrays are configured to receive a first DC voltage and generate a second potential upon the receipt of the first DC voltages. The first and second generated potential manipulate movement of ions.Type: ApplicationFiled: May 2, 2016Publication date: September 6, 2018Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Sandilya V.B. Garimella, Richard. D. Smith
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Patent number: 10018592Abstract: Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially according to their mobilities. A second intermittent traveling wave is applied for regrouping or merging the dispersed ion packets into a lesser number of trapping regions with narrower peaks. The ions packets are compressed into the narrower peak regions by varying a duty cycle of the intermittent traveling wave.Type: GrantFiled: May 17, 2016Date of Patent: July 10, 2018Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Sandilya Garimella, Richard D. Smith
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Patent number: 9966244Abstract: An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area.Type: GrantFiled: October 23, 2017Date of Patent: May 8, 2018Assignee: Battelle Memorial InstituteInventors: Gordon A. Anderson, Erin M. Baker, Richard D. Smith, Yehia M. Ibrahim
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Patent number: 9939409Abstract: Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.Type: GrantFiled: August 3, 2016Date of Patent: April 10, 2018Assignee: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Sandilya Garimella, Spencer A. Prost
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Publication number: 20180068839Abstract: An apparatus includes a first pair of opposing electrode arrangements that confine ions between them in a portion of a confinement volume inwardly laterally in a first confinement direction with respect to a longitudinal ion propagation direction, each opposing electrode arrangement including an arrangement of RF electrodes situated to receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes of the arrangement of RF electrodes so as to provide the confining of ions between the first pair of opposing electrode arrangements, and a second pair of opposing electrode arrangements that confine the ions between the second pair in the confinement volume inwardly laterally in a second confinement direction that complements the first confinement direction, each opposing electrode arrangement of the second pair including an arrangement of RF electrodes that receive an unbiased RF voltage having an alternate phase between adjacent RF electrodes.Type: ApplicationFiled: September 8, 2016Publication date: March 8, 2018Applicant: Battelle Memorial InstituteInventors: Yehia M. Ibrahim, Richard D. Smith