Abstract: The present invention discloses a pharmaceutical topical composition comprising cannabidiol (CBD) or a derivative thereof and Tetrahydrocannabinol (THC) or a derivative thereof in an about 1:1 ratio, useful for treatment or prevention of inflammatory skin disorders, and treatment methods thereof.

Abstract: The present invention discloses a composition comprising cannabis natural extract, or synthetic cannabinoids, for use in treating a subject suffering from fibromyalgia. The present invention further discloses methods and uses of the aforementioned composition.

Abstract: The present invention discloses a pharmaceutical topical composition comprising cannabidiol (CBD) or a derivative thereof and Tetrahydrocannabinol (THC) or a derivative thereof in an about 1:1 ratio, useful for treatment or prevention of inflammatory skin disorders, and treatment methods thereof.

Abstract: The present invention discloses a pharmaceutical composition comprising therapeutically effective amount of, or an extract consisting essentially therapeutically effective amount of at least one cannabinoid selected from the group consisting of: Cannabidiol (CBD) or a derivative thereof, Tetrahydrocannabinol (THC) or a derivative thereof, and any combination thereof, for use in the treatment of multiple myeloma (MM). The present invention further discloses methods and uses of the aforementioned composition.

Abstract: The present invention discloses a composition comprising a therapeutically effective amount of Tetrahydrocannabinol (THC) or a derivative thereof, or Cannabidiol (CBD) or a derivative thereof, or a combination thereof for use in relieving migraine attack of a patient. The present invention further discloses methods for relieving migraine attack symptoms using the afore-mentioned composition.

Abstract: The present invention discloses a cytotoxic cocktail comprising; (a) a therapeutically effective amount of at least one cannabinoid selected from the group consisting of: cannabidiol (CBD) or a derivative thereof, Tetrahydrocannabinol (THC) or a derivative thereof, and any combination thereof; and (b) at least one therapeutic agent selected from the group consisting of: bortezomib (BTZ), carflizomib (CFZ), lenalidomide (LEN), dexamethasone (DEX), melphalan (MEL) and doxorubicin (DOXO). In a core embodiment the cocktail is conferring a synergistic effect with respect to inhibition or cytotoxicity of multiple myeloma (MM) cells, relative to said at least one therapeutic agent selected from the group consisting of: BTZ, CFZ, LEN, DEX, MEL, DOXO and said CBD and THC, administered separately in a similar concentration.

Abstract: The present invention discloses a composition comprising cannabis natural extract, or synthetic cannabinoids, for use in treating a subject suffering from fibromyalgia. The present invention further discloses methods and uses of the aforementioned composition.

Abstract: The present invention discloses a cannabis based emulsion formulation for use in various medical conditions and optionally with various pharmaceutical or nutraceutical compositions, wherein the oily fraction used contains about 50% cannabinoids. The present invention further discloses methods of manufacturing and uses of the aforementioned composition.

Abstract: The present invention discloses a pharmaceutical topical composition comprising cannabidiol (CBD) or a derivative thereof and Tetrahydrocannabinol (THC) or a derivative thereof in an about 1:1 ratio, useful for treatment or prevention of inflammatory skin disorders, and treatment methods thereof.

Abstract: The present invention provides a biocompatible polymer or biocompatible material or composition for forming at least part of the structure of a condom useful for preventing STI's. The biocompatible polymer incorporates cannabis or cannabis derived compositions. The present invention also provides a biocompatible additive for condoms incorporating cannabis or cannabis derived compositions in a carrier or excipient. In addition, the biocompatible polymer or biocompatible additive incorporating cannabis or cannabis derived compositions enhances pleasure during the sexual act. Lastly, the biocompatible polymer or biocompatible additive incorporating cannabis or cannabis derived compositions can be used for the treatment of erectile dysfunction.

Abstract: A lockable hydraulic valve for preventing unauthorized use of a system, machinery item or vehicle requiring operation by both electric and hydraulic circuits. The valve comprising a housing provided with a spool bore and at least one hydraulic inlet and at least one hydraulic outlet. A spool allows oil passage from inlet to outlet in a first spool position. A key can drive the spool 90 degrees from a second, locked position to a first open position. A lock member in a hollow provided in the solid housing, engages and revolves the spool and also serves to block access to the exposed end of the spool. A locator member prevents axial movement of the spool member and locates in a spool groove. A non-central spool projection projects outward and operates at least one electric switch to immobilize at least one essential electric circuit simultaneously to the blocking of oil flow.

Abstract: The invention relates to vehicle theft prevention. The invention provides a pneumatic method of preventing the theft of drawn load carriers such as wagons/trailers and semitrailers. Some embodiments of invention comprise a wheeled load carrier of the type fitted with spring-closed pneumatically-opened brakes, the carrier being connectable to a motorized truck section, the carrier having an anti-theft protection device, which when deployed inhibits the unlocking of air-release spring-operated wheel brakes of the carrier, the device including a lockable air valve inserted into a compressed air line connecting a source of compressed air to the brakes, closure of the valve preventing air passage for release of the brakes and opening of the valve allowing passage for compressed air to release the brakes.

Abstract: A system for installation in mechanized vehicles which have an hydraulic brake system prevents the unauthorized operation of such vehicles and includes a valve of a special construction which comprises a housing provided with inlet ports and outlet ports for the hydraulic fluid, and an inner core member which is movable within the housing and is provided with bores which correspond with the ports in the housing forming a passage. Further, the valve includes at least one by-pass passage provided with a one way valve, the inner core member is movable rotatively or axially within the housing, and is connected to a key operated lock.