Patents by Inventor Yehuda Shoenfeld

Yehuda Shoenfeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230338461
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: May 8, 2023
    Publication date: October 26, 2023
    Inventors: Yehuda SHOENFELD, Miriam BLANK
  • Patent number: 11696935
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: July 11, 2023
    Assignee: TPCERA LTD.
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Patent number: 11458186
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: October 4, 2022
    Assignee: TPCERA LTD.
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Publication number: 20210161992
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: November 23, 2020
    Publication date: June 3, 2021
    Inventors: Yehuda SHOENFELD, Miriam BLANK
  • Publication number: 20210069284
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 11, 2021
    Inventors: Yehuda SHOENFELD, Miriam BLANK
  • Patent number: 10881707
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: January 5, 2021
    Assignee: TPCERA LTD.
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Patent number: 10842844
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: November 24, 2020
    Assignee: TPCERA LTD.
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Publication number: 20180353566
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 13, 2018
    Inventors: Yehuda SHOENFELD, Miriam BLANK
  • Publication number: 20180280466
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: May 29, 2018
    Publication date: October 4, 2018
    Inventors: Yehuda SHOENFELD, Miriam BLANK
  • Patent number: 10046021
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: August 14, 2018
    Assignee: TPCERA LTD.
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Patent number: 10040869
    Abstract: Specific peptides have been discovered that mimic an idiotype of an autoantibody. Such peptides may be formed into polymers. The peptides may be used in pharmaceutical compositions for the treatment of an autoimmune disease together with a pharmaceutically acceptable excipient.
    Type: Grant
    Filed: May 26, 2013
    Date of Patent: August 7, 2018
    Assignee: OMRIX BIOPHARMACEUTICALS LTD.
    Inventors: Israel Nur, Yehuda Shoenfeld, Miri Blank
  • Patent number: 9987372
    Abstract: The present invention provides phosphorylcholine (PC)-conjugates and pharmaceutical compositions, particularly vaccines comprising same for the prevention or treatment of autoimmune diseases. In particular, the PC-conjugates of the present invention are effective in preventing or treating autoimmune diseases associated with pathological inflammation.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: June 5, 2018
    Assignee: TPCERA LTD.
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Patent number: 9975944
    Abstract: The present invention provides synthetic peptides, including peptides comprising a plurality of epitopes, each epitope being derived from a different protein, and peptides comprising a plurality of citrullinated residues. The present invention also related to use of said peptides for the treatment of autoimmune diseases and disorder.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: May 22, 2018
    Assignee: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
    Inventors: Yehuda Shoenfeld, Howard Amital, Smadar Gertel
  • Publication number: 20160256516
    Abstract: The present invention provides phosphorylcholine conjugates and pharmaceutical compositions comprising same for the prevention or treatment of autoimmune diseases. In particular, the conjugates of the present invention are effective in treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: December 1, 2015
    Publication date: September 8, 2016
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Publication number: 20160193350
    Abstract: The present invention provides phosphorylcholine (PC)-conjugates and pharmaceutical compositions, particularly vaccines comprising same for the prevention or treatment of autoimmune diseases. In particular, the PC-conjugates of the present invention are effective in preventing or treating autoimmune diseases associated with pathological inflammation.
    Type: Application
    Filed: February 5, 2014
    Publication date: July 7, 2016
    Inventors: Yehuda Shoenfeld, Miriam Blank
  • Publication number: 20160024183
    Abstract: The present invention provides synthetic peptides, including peptides comprising a plurality of epitopes, each epitope being derived from a different protein, and peptides comprising a plurality of citrullinated residues. The present invention also related to use of said peptides for the treatment of autoimmune diseases and disorder.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 28, 2016
    Inventors: Yehuda Shoenfeld, Howard Amital, Smadar Gertel
  • Publication number: 20130244925
    Abstract: Specific peptides have been discovered that mimic an idiotype of an autoantibody. Such peptides may be formed into polymers. The peptides may be used in pharmaceutical compositions for the treatment of an autoimmune disease together with a pharmaceutically acceptable excipient.
    Type: Application
    Filed: May 26, 2013
    Publication date: September 19, 2013
    Applicant: Omrix Biopharmaceuticals Inc.
    Inventors: Israel NUR, Yehuda SHOENFELD, Miri BLANK
  • Patent number: 8450067
    Abstract: A method for identifying molecules which mimic an idiotype of an autoimmune disease-associated auto-antibody (autoantibodies). The method comprises the following steps: (a) purifying autoantibodies from sera of one or more patients afflicted with the autoimmune disease; (b) binding the autoantibodies to a solid phase to form an affinity matrix; (c) contacting pooled plasma or B cells comprising immunoglobulins with the affinity matrix followed by removal of unbound plasma components; (d) eluting bound immunoglobulins, being anti-Idiotypic antibodies (anti-Id) to autoantibodies, from the matrix; (e) providing a molecular library comprising a plurality of molecule members; and (e) contacting the anti-Id with the molecular library and isolating those bound molecules which are bound by the anti-Id, the bound molecules being molecules which mimic an idiotype of autoantibodies. Also disclosed are such molecules.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: May 28, 2013
    Assignee: Omrix Biopharmaceuticals Inc.
    Inventors: Israel Nur, Yehuda Shoenfeld, Miri Blank
  • Publication number: 20110064738
    Abstract: This invention relates to IVIG and fragments thereof and their use, specifically, provided herein are compositions and methods of inhibiting VEGF or VEGF receptor using polyclonal antibodies (pAb), or fragments thereof derived from human immunoglobulins.
    Type: Application
    Filed: June 24, 2010
    Publication date: March 17, 2011
    Inventors: Miri BLANK, Yehuda SHOENFELD
  • Publication number: 20100260760
    Abstract: This invention relates to IVIG and fragments thereof and their use, specifically, provided herein are compositions and methods of inhibiting VEGF or VEGF receptor using polyclonal antibodies (pAb), or fragments thereof derived from human immunoglobulins.
    Type: Application
    Filed: November 12, 2009
    Publication date: October 14, 2010
    Inventors: Miri Blank, Yehuda Shoenfeld