Patents by Inventor Yejun Tan

Yejun Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8744778
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: June 3, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Yejun Tan, Hongyue Dai, Pek Yee Lum, John Ryan Thompson, Joel Peter Berger, Eric Stanley Muise, Richard F. Raubertas, Kenny Kin Chung Wong
  • Publication number: 20110294696
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 1, 2011
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Yejun Tan, Hongyue Dai, Pek Yee Lum, John Ryan Thompson, Joel Peter Berger, Eric Stanley Muise, Richard F. Raubertas, Kenny Kin Chung Wong
  • Patent number: 8014954
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: September 6, 2011
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Yejun Tan, Hongyue Dai, Pek Yee Lum, John Ryan Thompson, Joel Peter Berger, Eric Stanley Muise, Richard F Raubertas, Kenny Kin Chung Wong
  • Publication number: 20060240457
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Application
    Filed: April 4, 2006
    Publication date: October 26, 2006
    Applicants: Rosetta Inpharmatics LLC, Merck & Co., Inc.
    Inventors: Yejun Tan, Hongyue Dai, Pek Lum, John Thompson, Joel Berger, Eric Muise, Richard Raubertas, Kenny Wong
  • Publication number: 20050084872
    Abstract: In one aspect, the present invention provides methods for determining whether an agent (e.g., candidate drug) possesses a biological activity. In another aspect, the present invention provides populations of nucleic acid molecules useful in the practice of the present invention as probes for measuring the level of expression of populations of genes.
    Type: Application
    Filed: January 23, 2004
    Publication date: April 21, 2005
    Inventors: Pek Lum, Yejun Tan, Hongyue Dai, Eric Muise, Joel Berger, John Thompson