Patents by Inventor Yeli Zhang

Yeli Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6583219
    Abstract: A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide (e.g., dextran) containing hydroxy groups which are reacted with unsaturated group introducing compound, is convertible by free radical polymerization to form a hydrogel containing a three dimensional crosslinked polymer network containing hydrophobic and hydrophilic components. Agent can be entrapped in the polymer network, e.g., drugs, macromolecules or synthetic or natural polymers, for controlled release therefrom.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: June 24, 2003
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Chee-Youb Won, Yeli Zhang, Chih-Chang Chu
  • Publication number: 20030008971
    Abstract: A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide containing hydroxy groups which are reacted with unsaturated group introducing compound, is convertible by free radical polymerization to form a hydrogel containing a three dimensional crosslinked polymer network containing hydrophobic and hydrophilic components. Agent can be entrapped in the polymer network, e.g., drugs, macromolecules or synthetic or natural polymers, for controlled release therefrom In one embodiment, a vascular stent is coated with hydrogel with therapeutic agent entrapped therein.
    Type: Application
    Filed: May 13, 2002
    Publication date: January 9, 2003
    Inventors: Chee-Youb Won, Yeli Zhang, Chih-Chang Chu
  • Publication number: 20020161169
    Abstract: A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide (e.g., dextran) containing hydroxy groups which are reacted with unsaturated group introducing compound, is convertible by free radical polymerization to form a hydrogel containing a three dimensional crosslinked polymer network containing hydrophobic and hydrophilic components. Agent can be entrapped in the polymer network, e.g., drugs, macromolecules or synthetic or natural polymers, for controlled release therefrom.
    Type: Application
    Filed: March 13, 2002
    Publication date: October 31, 2002
    Inventors: Chee-Youb Won, Yeli Zhang, Chih-Chang Chu
  • Patent number: 6388047
    Abstract: A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide containing hydroxy groups which are reacted with unsaturated group introducing compound, is convertible by free radical polymerization to form a hydrogel containing a three dimensional crosslinked polymer network containing hydrophobic and hydrophilic components. Preferably, the hydrophobic polymer is prepared by reacting the hydroxyls of a diol obtained by converting hydroxy of terminal carboxylic acid group of poly(lactic acid) to aminoethanol group, with an unsaturated group introducing compound which is acryloyl chloride or isocyanate having an unsaturated group at one end of the molecule.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: May 14, 2002
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Chee-Youb Won, Yeli Zhang, Chih-Chang Chu