Patents by Inventor Yeliu WANG

Yeliu WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240425529
    Abstract: Disclosed is a boronic acid derivative. Provided are a compound of formula (I) or a pharmaceutically acceptable salt, solvate, polymorph or isomer thereof, a pharmaceutical composition containing the same, and the use thereof in the treatment of lmp7-related diseases.
    Type: Application
    Filed: October 13, 2022
    Publication date: December 26, 2024
    Inventors: Yeliu WANG, Chang LU, Sheng ZHAO, Jijun LI, Weinan HE, Hongjuan LI
  • Patent number: 12030880
    Abstract: The present invention relates to a iminosulfanone compound represented by formula (I) as a bromodomain protein inhibitor and a pharmaceutically acceptable salt thereof and to a preparation method, pharmaceutical composition, and medical use thereof.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: July 9, 2024
    Assignees: Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Shouyao Holdings (Beijing) Co., Ltd., Lianyungang Runzhong Pharmaceutical Co., Ltd.
    Inventors: Jijun Li, Yan Zhu, Yeliu Wang, Xianxing Shang, Huting Wang, Weinan He, Qin Yan, Yinghui Sun, Kai Zhang, Chang Lu, Hongjiang Xu, Xin Tian, Ling Yang
  • Publication number: 20220194960
    Abstract: The present invention relates to a WEE1 inhibitor, and the preparation and use thereof. The WEE1 inhibitor of the present invention is a compound of Formula I or a compound of Formula II, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof. The present invention also provides use of the WEE1 inhibitor in the manufacture of a medicament for the treatment of a disease associated with WEE1 activity. The WEE1 inhibitor provided by the present invention can effectively treat the disease associated with WEE1 activity.
    Type: Application
    Filed: March 20, 2020
    Publication date: June 23, 2022
    Inventors: Yan Zhu, Jinsuo Yao, Yeliu Wang, Qin Yan, Weinan He, Changjun Chen, Xianxing Shang, Jijun Li, Yinghui Sun, Hongjuan Li, Chang Lu, Jiuqing Zhang, Deng Hou, Xiaojun Zhang, Qichao Liu
  • Publication number: 20210300923
    Abstract: The present invention relates to a sulfoximine compound represented by formula (I) as a bromodomain protein inhibitor and a pharmaceutically acceptable salt thereof and to a preparation method, pharmaceutical composition, and medical use thereof.
    Type: Application
    Filed: July 25, 2019
    Publication date: September 30, 2021
    Inventors: Jijun LI, Yan ZHU, Yeliu WANG, Xianxing SHANG, Huting WANG, Weinan HE, Qin YAN, Yinghui SUN, Kai ZHANG, Chang LU, Hongjiang XU, Xin TIAN, Ling YANG