Patents by Inventor Yen-Chu Lin

Yen-Chu Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Structure-based deep generative model for binding site descriptors extraction and de novo molecular generation
    Patent number: 12380329
    Abstract: In some aspects, the present disclosure describes a method of sampling a ligand. In some embodiments, the method comprises receiving a target descriptor. In some embodiments, the method comprises generating, in an engineered chemical space, a latent descriptor, based at least in part on the target descriptor. In some embodiments, the method comprises generating a ligand descriptor, based at least in part on the latent descriptor.
    Type: Grant
    Filed: March 1, 2023
    Date of Patent: August 5, 2025
    Assignee: INSILICO MEDICINE IP LIMITED
    Inventors: Ya-Chu Yang, Tzu-Lan Yeh, Yen-Chu Lin
  • STRUCTURE-BASED DEEP GENERATIVE MODEL FOR BINDING SITE DESCRIPTORS EXTRACTION AND DE NOVO MOLECULAR GENERATION
    Publication number: 20230281443
    Abstract: In some aspects, the present disclosure describes a method of sampling a ligand. In some embodiments, the method comprises receiving a target descriptor. In some embodiments, the method comprises generating, in an engineered chemical space, a latent descriptor, based at least in part on the target descriptor. In some embodiments, the method comprises generating a ligand descriptor, based at least in part on the latent descriptor.
    Type: Application
    Filed: March 1, 2023
    Publication date: September 7, 2023
    Inventors: Ya-Chu Yang, Tzu-Lan Yeh, Yen-Chu Lin