Patents by Inventor Yen Hsien Lee

Yen Hsien Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240118178
    Abstract: A staining kit is provided, including a first pattern including antibodies against T cell, B cell, NK cell, monocyte, regulatory cell, CD8, CD45, and CTLA4; a second pattern including antibodies against T cell, B cell, NK cell, monocyte, regulatory cell, dendritic cell, and CD45; a third pattern including antibodies against T cell, B cell, NK cell, monocyte, CD8, CD45, CD45RA, CD62L, CD197, CX3CR1 and TCR??; and a fourth pattern including antibodies against B cell, CD23, CD38, CD40, CD45 and IgM, wherein the antibodies of each pattern are labeled with fluorescent dyes. A method of identifying characterized immune cell subsets of a disease and a method of predicting the likelihood of NPC in a subject in the need thereof using the staining kit are also provided.
    Type: Application
    Filed: October 5, 2022
    Publication date: April 11, 2024
    Applicant: FULLHOPE BIOMEDICAL CO., LTD.
    Inventors: Jan-Mou Lee, Li-Jen Liao, Yen-Ling Chiu, Chih-Hao Fang, Kai-Yuan Chou, Pei-Hsien Liu, Cheng-Yun Lee
  • Publication number: 20240087980
    Abstract: A semiconductor device includes a substrate, a dielectric layer disposed over the substrate, and an interconnect structure extending through the dielectric layer. The dielectric layer includes a low-k dielectric material which includes silicon carbonitride having a carbon content ranging from about 30 atomic % to about 45 atomic %. The semiconductor device further includes a thermal dissipation feature extending through the dielectric layer and disposed to be spaced apart from the interconnect structure.
    Type: Application
    Filed: February 17, 2023
    Publication date: March 14, 2024
    Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventors: Kai-Fang CHENG, Cherng-Shiaw TSAI, Cheng-Chin LEE, Yen-Ju WU, Yen-Pin HSU, Li-Ling SU, Ming-Hsien LIN, Hsiao-Kang CHANG
  • Publication number: 20230031385
    Abstract: A corneal storage composition is disclosed. The composition comprises a buffered, balanced, nutrient and electrolyte aqueous solution; ?-PGA; and ferulic acid, in amounts effective to maintain cell integrity and viability of the corneal tissue for a period of greater than 14 days.
    Type: Application
    Filed: July 20, 2021
    Publication date: February 2, 2023
    Inventors: Feng-Huei LIN, Yu-Chun CHEN, Wen-Yu SU, Yen-Hsien LEE, Ko-Hua CHEN
  • Patent number: 10426343
    Abstract: A physiology detecting garment, a physiology detecting monitoring system, and a manufacturing method of a textile antenna are provided. The physiology detecting garment detects and collects physiology information of a wearer. The physiology detecting garment includes a garment, a textile antenna and a detecting device. The textile antenna is made of a conductive composition including a conductive nanowire and a polyurethane polymer. The textile antenna is thermal-compression bonded to the garment. The detecting device is electrically connected to the textile antenna and emits a detecting signal via the textile antenna.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: October 1, 2019
    Assignee: Industrial Technology Research Institute
    Inventors: Hong-Dun Lin, Wen-Hsien Sun, Yong-Syuan Chen, Chih-Lung Chen, Yen-Hsien Lee, Pei-Fen Zhen, Jing-Wen Tang
  • Patent number: 9877659
    Abstract: A sensing system for physiology measurements comprises a transmission end including a measuring signal generating module having at least one overshoot and undershoot wave generating circuits and a transmitting antenna module having at least one transmitting antenna; a receiving end having a plurality of receiving antennae with each receiving antenna receiving a reflected signal reflected by a target object; and a plurality of signal analyzing modules to generate a plurality of object active state signals by analyzing the reflected signal from each receiving antenna and transmit the plurality of object active state signals to a digital signal processor. Wherein each overshoot and undershoot wave generating circuit generates a measuring signal with overshoot and undershoot waves according to an inputted Pulse Width Modulation signal, and each transmitting antenna emits the measuring signal to the target object.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: January 30, 2018
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yen-Hsien Lee, Hong-Dun Lin, Wen-Jen Tseng
  • Publication number: 20170265743
    Abstract: A physiology detecting garment, a physiology detecting monitoring system, and a manufacturing method of a textile antenna are provided. The physiology detecting garment detects and collects physiology information of a wearer. The physiology detecting garment includes a garment, a textile antenna and a detecting device. The textile antenna is made of a conductive composition including a conductive nanowire and a polyurethane polymer. The textile antenna is thermal-compression bonded to the garment. The detecting device is electrically connected to the textile antenna and emits a detecting signal via the textile antenna.
    Type: Application
    Filed: August 22, 2016
    Publication date: September 21, 2017
    Inventors: Hong-Dun Lin, Wen-Hsien Sun, Yong-Syuan Chen, Chih-Lung Chen, Yen-Hsien Lee, Pei-Fen Zhen, Jing-Wen Tang
  • Publication number: 20170156645
    Abstract: A non-invasive blood glucose measuring device and a measuring method using the same are provided. The non-invasive blood glucose measuring device includes a signal emitting module, a delay component, a wave mixing component and a signal processor. The signal emitting module is configured to emit a detection signal. The delay component is configured to delay the detection signal to become a delay signal. The wave mixing component is configured to mix a return signal and the delay signal to form a mixed signal, wherein the return signal is the detection signal reflected from an object. The signal processor is configured to obtain a blood glucose level of the object according to the mixed signal.
    Type: Application
    Filed: December 28, 2015
    Publication date: June 8, 2017
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hong-Dun Lin, Yen-Hsien Lee
  • Publication number: 20170150894
    Abstract: A device and a system for physiological measurements are disclosed. The device includes two light-emitting units and a detection unit. Each one of the two light-emitting units provides a light beam projecting to respective one of two positions of a limb. The detection unit receives the reflected lights from the projected positions of the limb and transfers the received lights out as measuring signals.
    Type: Application
    Filed: November 22, 2016
    Publication date: June 1, 2017
    Inventors: Hong-Dun Lin, Yen-Hsien Lee
  • Publication number: 20170020463
    Abstract: A method processed by a signal processing device of a physiology measuring system includes calculating a pulse time difference of a first pulse peak and a second pulse peak; calculating a pulse wave velocity; and calculating a systolic blood pressure of an artery, and a diastolic blood pressure of the artery; wherein the first pulse peak and the second pulse peak is generated by a sensing device; wherein the sensing device emits a plurality of first radiated pulse signals to a first measure point of the artery and, in turn, receiving a plurality of first scattered pulse signals reflected from the first measure point of the artery; and wherein the sensing device emits a plurality of second radiated pulse signals to a second measure point of the artery and, in turn, receiving a plurality of second scattered pulse signals from the second measure point of the artery.
    Type: Application
    Filed: October 4, 2016
    Publication date: January 26, 2017
    Inventors: HONG DUN LIN, YEN HSIEN LEE
  • Patent number: 9457000
    Abstract: Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) ?-polyglutamic acid (?-PGA) and/or salt thereof in an amount effective to increase the viscosity of the irrigating solution, and b) an ophthalmically acceptable aqueous vehicle for the ?-PGA and/or salt thereof. Also disclosed is a method of irrigating ocular tissues of a patient, in which the method comprises introducing to the ocular tissues of the patient an ophthalmic irrigating solution comprising ?-PGA) and/or salt thereof in an amount sufficient to irrigate the ocular tissues of the patient.
    Type: Grant
    Filed: June 16, 2013
    Date of Patent: October 4, 2016
    Assignee: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin
  • Patent number: 9134404
    Abstract: An electronic device and a method for sensing an active state of an object are provided; the electronic device includes a signal generating module, a non-symmetric antenna module and a signal analyzing module. The signal generating module is configured to generate a pulse width modulation signal, generate a measuring signal with overshoot and undershoot pulses according to the pulse width modulation signal, and generate a reference signal according to the measuring signal. The non-symmetric antenna module includes a transmitting antenna and a receiving antenna. The transmitting antenna is configured to transmit the measuring signal to an object. The receiving antenna is configured to receive the measuring signal reflected by the object. The signal analyzing module is configured to receive and process the reference signal and the measuring signal reflected by the object, so as to obtain an object active state signal.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: September 15, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Yen-Hsien Lee, Wen-Jen Tseng, Hong-Dun Lin
  • Patent number: 9033892
    Abstract: A method for predicting drowsiness is disclosed. By obtaining average heart beat rate values of a driver, and according to the characteristics of the heart beat rate values over a period of time, the method is utilized to determine whether the human being is going to sleep. The method comprises the following steps: detecting a heart beat rate of a driver; calculating a curve of the heart beat rate average during a time interval of X minutes; determining an accumulated length of duration during which the calculated linear regression slope values are smaller than the predetermined slope value Z; determining whether the accumulated length of duration is greater than a time threshold T to generate a drowsiness detecting result; and determining whether to raise an alarm based on the drowsiness detecting result.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: May 19, 2015
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yu Jen Su, Yen Hsien Lee, Kuang I Chang
  • Publication number: 20140343393
    Abstract: A sensing system for physiology measurements comprises a transmission end including a measuring signal generating module having at least one overshoot and undershoot wave generating circuits and a transmitting antenna module having at least one transmitting antenna; a receiving end having a plurality of receiving antennae with each receiving antenna receiving a reflected signal reflected by a target object; and a plurality of signal analyzing modules to generate a plurality of object active state signals by analyzing the reflected signal from each receiving antenna and transmit the plurality of object active state signals to a digital signal processor. Wherein each overshoot and undershoot wave generating circuit generates a measuring signal with overshoot and undershoot waves according to an inputted Pulse Width Modulation signal, and each transmitting antenna emits the measuring signal to the target object.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 20, 2014
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yen-Hsien LEE, Hong-Dun LIN, Wen-Jen TSENG
  • Publication number: 20140236540
    Abstract: A signal processing method and a signal processing system are provided. The signal processing method comprises the following steps. An original signal is provided. The original signal is gradually divided to be corresponding a plurality of stages. One high frequency signal and one low frequency signal whose frequency is lower than that of the high frequency signal are corresponding one of the stages. One of the low frequency signals corresponding to one of the stages is divided into another one of the high frequency signals and another one of the low frequency signals corresponding to the next one of the stages. An adjusting signal is obtained by filtering one of the low frequency signals out of another one of the low frequency signals.
    Type: Application
    Filed: July 10, 2013
    Publication date: August 21, 2014
    Inventors: Jun-Jie Chen, Yen-Hsien Lee, Hong-Dun Lin
  • Publication number: 20140171811
    Abstract: The current disclosure discloses a physiology measuring system comprising a sensing device and a signal processing device. The sensing device comprises a first antenna, a second antenna, a first pulse signal generator, a second pulse signal generator, a first pulse signal receiver, a second pulse signal receiver and a first wireless module. The signal processing device further comprises a second wireless module and a microcontroller having a calculation unit which has an algorithm. The first wireless module communicates with the second wireless module via a wireless protocol.
    Type: Application
    Filed: December 13, 2012
    Publication date: June 19, 2014
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: HONG DUN LIN, YEN HSIEN LEE
  • Publication number: 20140152491
    Abstract: An electronic device and a method for sensing an active state of an object are provided; the electronic device includes a signal generating module, a non-symmetric antenna module and a signal analyzing module. The signal generating module is configured to generate a pulse width modulation signal, generate a measuring signal with overshoot and undershoot pulses according to the pulse width modulation signal, and generate a reference signal according to the measuring signal. The non-symmetric antenna module includes a transmitting antenna and a receiving antenna. The transmitting antenna is configured to transmit the measuring signal to an object. The receiving antenna is configured to receive the measuring signal reflected by the object. The signal analyzing module is configured to receive and process the reference signal and the measuring signal reflected by the object, so as to obtain an object active state signal.
    Type: Application
    Filed: January 16, 2013
    Publication date: June 5, 2014
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yen-Hsien Lee, Wen-Jen Tseng, Hong-Dun Lin
  • Publication number: 20130273186
    Abstract: Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) ?-polyglutamic acid (?-PGA) and/or salt thereof in an amount effective to increase the viscosity of the irrigating solution, and b) an ophthalmically acceptable aqueous vehicle for the ?-PGA and/or salt thereof. Also disclosed is a method of irrigating ocular tissues of a patient, in which the method comprises introducing to the ocular tissues of the patient an ophthalmic irrigating solution comprising ?-PGA) and/or salt thereof in an amount sufficient to irrigate the ocular tissues of the patient.
    Type: Application
    Filed: June 16, 2013
    Publication date: October 17, 2013
    Inventors: Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin
  • Patent number: 8439849
    Abstract: An intestinal peristalsis detecting device comprises a radio frequency (RF) signal generator, an antenna, and a mixer. After the RF signal generator sends a pulse signal, the antenna receives the pulse signal and emits a pulse electromagnetic wave to an organism. Thereafter, the antenna receives a response pulse electromagnetic wave reflected from the organism to generate a response pulse signal. The mixer couples with the RF signal generator and the antenna to mix the pulse signal and the response pulse signal.
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: May 14, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Hong Dun Lin, Yen Hsien Lee, Mu Yu Tsai, Yu Jen Su
  • Publication number: 20120296226
    Abstract: A method for predicting drowsiness is disclosed. By obtaining average heart beat rate values of a driver, and according to the characteristics of the heart beat rate values over a period of time, the method is utilized to determine whether the human being is going to sleep. The method comprises the following steps: detecting a heart beat rate of a driver; calculating a curve of the heart beat rate average during a time interval of X minutes; determining an accumulated period of time during which the slope values of the linear regression equations are smaller than the predetermined slope value Z; determining whether the length of the accumulated period of time is greater than a time threshold T to generate a drowsiness detecting result; and determining whether to raise an alarm based on the drowsiness detecting result.
    Type: Application
    Filed: September 26, 2011
    Publication date: November 22, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: YU JEN SU, YEN HSIEN LEE, KUANG I CHANG
  • Patent number: 8298141
    Abstract: A method for measuring physiological parameters uses statistical properties, spectrum analysis and feedback mechanisms to remove the signal noise generated by human body movement from a detected physiological signal.
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: October 30, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Tai Been Chen, Yen Hsien Lee, Mu Yu Tsai, Yu Jen Su