Patents by Inventor Yen-Pei Lu
Yen-Pei Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10786326Abstract: A surgical image pickup system utilizes an adjustable lens set and a complex lens set to change the direction of the incident light emitted from the light source and the position of the surgical site on which the incident light projects. The eyepiece and the sensor have the same field of view and the same optical axis such that first image generated by the sensor and a second image generated by the eyepiece are the same. The sensor transmits the first image to the external display for display by wireless communication. By means of the foregoing configuration, the second image which doctor utilizes the eyepiece to see and the first image which the external display displays are the same, thereby facilitating the operation of surgery.Type: GrantFiled: August 2, 2019Date of Patent: September 29, 2020Assignee: National Applied Research LaboratoriesInventors: Rui-Cian Weng, Yih-Sharng Chen, Te-I Chang, Chi-Hung Huang, Yen-Pei Lu, Yen-Song Chen, Kuan-Yin Yu
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Patent number: 10299678Abstract: An apparatus for detecting conductance parameter of high protein body fluid sample is provided. The apparatus includes at least one liquid collection element, and at least two electrodes horizontally aligned in the liquid collection element. Also provided are methods for detecting dehydration in a subject, comprising the steps of measuring the conductance parameter of the saliva of the subject.Type: GrantFiled: April 3, 2017Date of Patent: May 28, 2019Assignees: CHANG GUNG MEMORIAL HOSPITAL, CHIAYI, NATIONAL APPLIED RESEARCH LABORATORIES, NATIONAL TAIWAN UNIVERSITYInventors: Jen-Tsung Yang, Leng-Chieh Lin, I-Neng Lee, Jo-Wen Huang, Jer-Liang Andrew Yeh, Ming-Yu Lin, Yen-Pei Lu, Chih-Ting Lin, Chia-Hong Gao
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Patent number: 10036704Abstract: A fluorescence intensity analyzing and fluorescence image synthesizing system and method are disclosed. The first fluorescence intensity detection device successively detects the plurality of first fluorescence intensities according to the first timing and the second fluorescence intensity detection device successively detects the plurality of second fluorescence intensities according to the second timing, and then the picture processing device analyzes the first and second timings and synthesizes the first and second fluorescence intensity ranges into the synthesized picture according to the fluorescence intensities, whereby the image processing technology may be used to calculate the fluorescence target range and thus mark the fluorescence target range.Type: GrantFiled: July 31, 2014Date of Patent: July 31, 2018Assignees: National Taiwan University, National Applied Research LaboratoriesInventors: Rui-Cian Weng, Min-Yu Lin, Chi-Hung Huang, Yen-Pei Lu, Wen-Shiang Chen, Chia-Wen Lo
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Publication number: 20170290509Abstract: An apparatus for detecting conductance parameter of high protein body fluid sample is provided. The apparatus includes at least one liquid collection element, and at least two electrodes horizontally aligned in the liquid collection element. Also provided are methods for detecting dehydration in a subject, comprising the steps of measuring the conductance parameter of the saliva of the subject.Type: ApplicationFiled: April 3, 2017Publication date: October 12, 2017Inventors: Jen-Tsung YANG, Leng-Chieh LIN, I-Neng LEE, Jo-Wen HUANG, Jer-Liang Andrew YEH, Ming-Yu LIN, Yen-Pei LU, Chih-Ting LIN, Chia-Hong GAO
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Publication number: 20160033409Abstract: A fluorescence intensity analyzing and fluorescence image synthesizing system and method are disclosed. The first fluorescence intensity detection device successively detects the plurality of first fluorescence intensities according to the first timing and the second fluorescence intensity detection device successively detects the plurality of second fluorescence intensities according to the second timing, and then the picture processing device analyzes the first and second timings and synthesizes the first and second fluorescence intensity ranges into the synthesized picture according to the fluorescence intensities, whereby the image processing technology may be used to calculate the fluorescence target range and thus mark the fluorescence target range.Type: ApplicationFiled: July 31, 2014Publication date: February 4, 2016Applicants: NATIONAL APPLIED RESEARCH LABORATORIES, NATIONAL TAIWAN UNIVERSITYInventors: Rui-Cian WENG, Min-Yu LIN, Chi-Hung HUANG, Yen-Pei LU, Wen-Shiang CHEN, Chia-Wen LO
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Patent number: 8921075Abstract: A method of manufacturing a nanoparticle chain is disclosed. The method comprises the steps of: providing a single-stranded circular primer with a determined length, and amplifying the single-stranded circular primer into single-stranded DNA nanotemplate by an isothermal nucleotide amplification reaction such that an end of the single-stranded DNA nanotemplate is fixed to a surface of a substrate; and adding a single-stranded DNA probe conjugated with nanoparticle at one end of which, and attaching the single-stranded DNA probe to the corresponding sequence on the single-stranded DNA nanotemplate to form a nanoparticles chain. The method of manufacturing a nanoparticle chain further comprises providing a fluid, and the flowing direction of the fluid controls the aligning direction of the nanoparticle chain. Wherein, the inter-nanoparticle distance of the nanoparticle chain can be adjusted by adjusting a reaction temperature or adding the single-stranded DNA probe without conjugating with nanoparticles.Type: GrantFiled: June 5, 2012Date of Patent: December 30, 2014Assignee: National Applied Research LaboratoriesInventors: Yen-Pei Lu, Ming-Yu Lin, Yu-Sheng Lai, Yuh-Shyong Yang, Hsuen-Li Chen, Yu-Cheng Ou
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Patent number: 8563245Abstract: A method that modifies surface properties of a substrate by manipulating the immobilized biomolecules in mild biological condition. The manipulation comprised steps of: providing a biomolecule combined with at least one ssDNA combined with a first protein through an affinity binding tag; adding a second ssDNA conjugated with a second protein with a concentration greater than that of the first protein; and replacing the first protein on the ssDNA with the second protein through chemical competitive principle. The invention may comprise the steps with proper design of biotinylated DNA probes, the functionalized ssDNA nanotemplates can be recovered to its unbound state through a thermodynamic principle.Type: GrantFiled: April 2, 2012Date of Patent: October 22, 2013Assignee: National Applied Research LaboratoriesInventors: Ming-Yu Liu, Yuh-Shyong Yang, Yen-Pei Lu, Chih-Heng Lin
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Publication number: 20130273610Abstract: A method of manufacturing a nanoparticle chain is disclosed. The method comprises the steps of: providing a single-stranded circular primer with a determined length, and amplifying the single-stranded circular primer into single-stranded DNA nanotemplate by an isothermal nucleotide amplification reaction such that an end of the single-stranded DNA nanotemplate is fixed to a surface of a substrate; and adding a single-stranded DNA probe conjugated with nanoparticle at one end of which, and attaching the single-stranded DNA probe to the corresponding sequence on the single-stranded DNA nanotemplate to form a nanoparticles chain. The method of manufacturing a nanoparticle chain further comprises providing a fluid, and the flowing direction of the fluid controls the aligning direction of the nanoparticle chain. Wherein, the inter-nanoparticle distance of the nanoparticle chain can be adjusted by adjusting a reaction temperature or adding the single-stranded DNA probe without conjugating with nanoparticles.Type: ApplicationFiled: June 5, 2012Publication date: October 17, 2013Applicant: NATIONAL APPLIED RESEARCH LABORATORIESInventors: Yen-Pei Lu, Ming-Yu Lin, Yu-Sheng Lai, Yuh-Shyong Yang, Hsuen-Li Chen, Yu-Cheng Ou
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Publication number: 20130210110Abstract: A method that modifies surface properties of a substrate by manipulating the immobilized biomolecules in mild biological condition. The manipulation comprised steps of: providing a biomolecule combined with at least one ssDNA combined with a first protein through an affinity binding tag; adding a second ssDNA conjugated with a second protein with a concentration greater than that of the first protein; and replacing the first protein on the ssDNA with the second protein through chemical competitive principle. The invention may comprise the steps with proper design of biotinylated DNA probes, the functionalized ssDNA nanotemplates can be recovered to its unbound state through a thermodynamic principle.Type: ApplicationFiled: April 2, 2012Publication date: August 15, 2013Applicant: NATIONAL APPLIED RESEARCH LABORATORIESInventors: Ming-Yu Lin, Yuh-Shyong Yang, Yen-Pei Lu, Chih-Heng Lin