Abstract: An upper rail device for a seat of a vehicle includes: a lower plate in which a slot is formed, a drive housing mounted on the lower plate, a drive support that passes through the slot for insertion into a curved movement path of a lower rail, a motor with a reducer mounted on an upper surface of the drive housing, a drive shaft connected to an output portion of the reducer, a drive gear mounted on a lower end portion of the drive shaft and engaged with a driven gear mounted within the curved movement path of the lower rail. The upper rail device may be fastened to enable sliding movement along the curved movement path of the lower rail so that the seat can be moved in a diagonal or oblique direction depending on various purposes, which can improve a seat position movement adjustment.

Abstract: The present disclosure relates to a novel heterocyclic amine derivative represented by the following Chemical Formula 1 and a pharmaceutical composition comprising the same, and the compound according to the present disclosure can be usefully used for the prevention or treatment of autoimmune diseases or cancers. wherein, in Chemical Formula 1, R1, R2, X1, X2, L, Y, A and B are the same as defined in the specification.

Abstract: The present invention relates to a monoclonal antibody or a fragment thereof that recognizes and binds specifically to the extracellular domain of endothelin receptor type A as an antigen. The monoclonal antibody of the present invention is suitable for use in a therapeutic agent for hypertension or cancer associated with endothelin receptor type A.

Abstract: The present disclosure relates to a high energy density lithium secondary battery having significantly improved high-temperature storage characteristics and lifespan characteristics, which are problematic when a silicon-based negative electrode active material is applied. Specifically, a lithium secondary battery according to an exemplary embodiment includes a positive electrode; a negative electrode facing the positive electrode and including a silicon-based negative electrode active material; and a non-aqueous electrolyte containing a non-aqueous organic solvent including a di-fluoro-based organic solvent and a lithium salt, wherein a content of the di-fluoro-based organic solvent is 5 to 20 vol % with respect to a total volume of the non-aqueous organic solvent.

Abstract: An anode for a secondary battery includes an anode current collector, a first anode active material layer disposed on at least one surface of the anode current collector and including a first anode active material that includes a first silicon composite oxide, and a second anode active material layer disposed on the first anode active material layer and including a second anode active material that includes a second silicon composite oxide. Each of the first silicon composite oxide and the second silicon composite oxide includes a metal. A BET specific surface area of each of the first silicon composite oxide and the second silicon composite oxide is in a range from 2.0 m2/g to 6.5 m2/g.

Abstract: A lower rail for a seat of a vehicle has a structure with a curved movement path, in which the seat may be moved in an oblique direction or a diagonal direction according to various seat positions, thereby allowing a degree of freedom for adjusting a seat position movement. In addition, the lower rail includes a curved inner channel bent at a predetermined angle and a curved outer channel bent at about a same angle as the curved inner channel, which are separately provided and configured to be mutually combined in order to provide one curved movement path for moving the seat.

Abstract: Provided is a single-stranded nucleic acid aptamer specifically binding to Klebsiella pneumoniae, and a method for detecting Klebsiella pneumoniae by using the same. The aptamer of the present disclosure, and a method, a composition, a kit or a sensor of using the same may be used to specifically detect Klebsiella pneumoniae present in an aqueous environment, foods, and medical samples and also be applied in fields such as sanitary conditions of foods and medical diagnosis.

Abstract: Provided is a single-stranded nucleic acid aptamer specifically binding to Klebsiella pneumoniae, and a method for detecting Klebsiella pneumoniae by using the same. The aptamer of the present disclosure, and a method, a composition, a kit or a sensor of using the same may be used to specifically detect Klebsiella pneumoniae present in an aqueous environment, foods, and medical samples and also be applied in fields such as sanitary conditions of foods and medical diagnosis.

Abstract: Provided are a single-stranded nucleic acid aptamer specifically binding to E. coli and a method for detecting E. coli using the same. The method, kits or sensors of the present disclosure enable E. coli to be specifically detected among microorganisms existing in a water system, but also be applied in fields such as food sanitation or medical diagnosis.

Abstract: The present invention relates to an apparatus and method for continuously monitoring subaqueous target harmful substances. More particularly, it relates to an apparatus and method for continuously monitoring subaqueous target harmful substances by continuously measuring the concentration of the subaqueous target harmful substances. The present invention provides an apparatus and method for continuously monitoring subaqueous target harmful substances, which can continuously measure the concentration of subaqueous target harmful substances using a receptor that can selectively recognize the target harmful substances, a porous membrane fixed with the receptor, and a sensing unit that continuously measures the intensity of fluorescent signals of the target harmful substance reacting with the receptor, and can be utilized as various apparatuses and methods for continuously sensing various harmful substances necessary to continuously monitor for the management of the water quality.

Abstract: Provided are a single-stranded nucleic acid aptamer specifically binding to E. coli and a method for detecting E. coli using the same. The method, kits or sensors of the present disclosure enable E. coli to be specifically detected among microorganisms existing in a water system, but also be applied in fields such as food sanitation or medical diagnosis.